Radioiodinated magnetic nanoparticles conjugated with moxifloxacin: Synthesis and in vitro biological affinities
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor and Francis Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Magnetic nanoparticles (MNPs) were synthesized and coated with tetraethyl orthosilicate and aminosilane to create functional amino groups. Moxifloxacin (MXF) was conjugated to the modified MNPs using glutaraldehyde as crosslinker. Finally, MXF conjugated magnetic nanoparticles were radiolabeled and their biological affinities such as cell incorporation ratio, cytotoxicity, and their potential as cell imaging probe were investigated using A-549 cells. © 2015 Copyright Taylor & Francis Group, LLC.
Açıklama
Anahtar Kelimeler
A549 cell line, bioconjugation, cell incorporation, Magnetic nanoparticles, moxifloxacin, radioiodination
Kaynak
International Journal of Polymeric Materials and Polymeric Biomaterials
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
64
Sayı
5
