Protective Effect of Hypothermia During Experimental Sepsis

Basit Öğe Kaydı
dc.contributor.authorKaraca, Iclal
dc.contributor.authorCankayali, Ilkin
dc.contributor.authorDemirag, Kubilay
dc.contributor.authorUyar, Mehmet
dc.date.accessioned2019-10-27T09:43:56Z
dc.date.available2019-10-27T09:43:56Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: In our study, we aimed to investigate the effect of hypothermia on survival, C-reactive protein (CRP), procalcitonin and leukocyte levels in rat models, induced with cecal ligation-perforation procedure. Materials and Methods: After formation of the sepsis, the rats were randomized as hypothermic sham, septic (32 degrees C-34 degrees C) and normothermic sham, septic (36 degrees C-38 degrees C). At the beginning of study (0 h) and at 6th hour blood was taken from all rats in all groups; CRP, procalcitonin, leukocyte levels were measured and the survival time of rats in all groups was recorded. Results: A statistically significant difference was found between the hypothermic and normothermic septic group in terms of survival time (hypothermic septic 24.3 +/- 20.2, normothermic septic group 15.9 +/- 13.5 h, p=0.039). There was no statistically significant difference for time dependent changes of CRP and procalcitonin all groups. Conclusion: It can be suggested that hypothermia in experimental sepsis might have positive effects on survival but the effect on the markers of infection is unclear and further studies are needed.en_US
dc.identifier.doi10.4274/tybd.galenos.2018.76094
dc.identifier.endpage87en_US
dc.identifier.issn2602-2974
dc.identifier.issn2602-2974en_US
dc.identifier.issue2en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org/10.4274/tybd.galenos.2018.76094
dc.identifier.urihttps://hdl.handle.net/11454/28936
dc.identifier.volume17en_US
dc.identifier.wosWOS:000470081700003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal of Intensive Care-Turk Yogun Bakim Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHypothermiaen_US
dc.subjectexperimentalen_US
dc.subjectRat modelen_US
dc.subjectsepsisen_US
dc.titleProtective Effect of Hypothermia During Experimental Sepsisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu