Electrochemical deposition of polypeptides: bio-based covering materials for surface design

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dc.contributor.authorAkbulut, Huseyin
dc.contributor.authorYavuz, Murat
dc.contributor.authorGuler, Emine
dc.contributor.authorDemirkol, Dilek Odaci
dc.contributor.authorEndo, Takeshi
dc.contributor.authorYamada, Shuhei
dc.contributor.authorTimur, Suna
dc.contributor.authorYagci, Yusuf
dc.date.accessioned2019-10-27T22:05:54Z
dc.date.available2019-10-27T22:05:54Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractA simple and efficient approach for the electrochemical deposition of polypeptides as bio-based covering materials for surface design is described. The method involves N-carboxyanhydride (NCA) ring-opening polymerization from its precursor to form a thiophene-functionalized polypeptide macromonomer (T-Pala), followed by electropolymerization. The obtained conducting polymer, namely polythiophene-g- polyalanine (PT-Pala), was characterized and utilized as a matrix for biomolecule attachment. The biosensing applicability of PT-Pala was also investigated by using glucose oxidase (GOx) as a model enzyme to detect glucose. The designed biosensor showed a very good linearity for 0.01-1.0 mM glucose. Finally, the antimicrobial activities of newly synthesized T-Pala and PT-Pala were also evaluated by using the disc diffusion method.en_US
dc.identifier.doi10.1039/c4py00079j
dc.identifier.endpage3936en_US
dc.identifier.issn1759-9954
dc.identifier.issn1759-9962
dc.identifier.issn1759-9954en_US
dc.identifier.issn1759-9962en_US
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3929en_US
dc.identifier.urihttps://doi.org/10.1039/c4py00079j
dc.identifier.urihttps://hdl.handle.net/11454/48642
dc.identifier.volume5en_US
dc.identifier.wosWOS:000336804800024en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherRoyal Soc Chemistryen_US
dc.relation.ispartofPolymer Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleElectrochemical deposition of polypeptides: bio-based covering materials for surface designen_US
dc.typeArticleen_US

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