Evaluation of Incidence and Characteristics of Necrotizing Enterocolitis in Neonatal Intensive Care Unit

Basit Öğe Kaydı
dc.contributor.authorBilgin, Betul Siyah
dc.contributor.authorTerek, Demet
dc.contributor.authorKoroglu, Ozge Altun
dc.contributor.authorYalaz, Mehmet
dc.contributor.authorAkisu, Mete
dc.contributor.authorCelik, Ahmet
dc.contributor.authorErgun, Orkan
dc.contributor.authorKultursay, Nilgun
dc.date.accessioned2019-10-27T11:23:26Z
dc.date.available2019-10-27T11:23:26Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: The aim of this study was to evaluate the risk factors, characteristic features, clinical and laboratory findings and mortality rates of necrotizing enterocolitis (NEC) patients. Materials and Methods: Thirty seven patients diagnosed with NEC among the 488 cases followed up in our clinic between 2010-2011 were included into this study. Results: The incidence of NEC was found as 7.5% among the total patient population. Mean gestational age and birth weight of NEC patients were 27.5 +/- 2.5 weeks and 1044 +/- 485 grams. Ninety percent of NEC patients were born under 1500 grams and 30 weeks. Twenty-four cases were classified as stage 1, and 13 cases were classified as stage 2-3. Stage 2-3 NEC was diagnosed in 9.8% of very low birth weight infants. The mean gestational age, birth weight, gender, delivery type, Apgar scores and the incidence of intrauterine growth restriction, diagnosis and/or treatment of patent ductus arteriosus, retinopathy of prematurity, respiratory distress syndrome, intracranial hemorrhage were similar between patients with different stages of NEC. Gastrointestinal perforation developed in six of the stage 2-3 cases. Platelet count and hematocrit levels were lower (p<0.01 and p=0.02); mortality rate was higher (p=0.02) in stage 2-3 patients when compared to stage 1 patients. Conclusion: NEC is more common in newborns with low birth weight and low gestational age. The severity of the illness is closely associated with laboratory abnormalities such as anemia, leucopenia, leukocytosis, thrombocytopenia and elevated C-reactive protein levels. Mortality risk is higher in advanced stages of the disease requiring surgery, and especially small babies.en_US
dc.identifier.doi10.4274/jpr.88700
dc.identifier.endpage202en_US
dc.identifier.issn2147-9445
dc.identifier.issn2147-9445en_US
dc.identifier.issue4en_US
dc.identifier.startpage196en_US
dc.identifier.urihttps://doi.org/10.4274/jpr.88700
dc.identifier.urihttps://hdl.handle.net/11454/33176
dc.identifier.volume3en_US
dc.identifier.wosWOS:000406929600007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal of Pediatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNewbornen_US
dc.subjectprematurityen_US
dc.subjectnecrotizing enterocolitisen_US
dc.subjectincidenceen_US
dc.subjectmortalityen_US
dc.titleEvaluation of Incidence and Characteristics of Necrotizing Enterocolitis in Neonatal Intensive Care Uniten_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu