A Novel Chronoimpedimetric Glucose Sensor in Real Blood Samples Modified by Glucose-Imprinted Pyrrole-Aminophenylboronic Acid Modified Screen Printed Electrode

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dc.contributor.authorUygun, Zihni Onur
dc.contributor.authorUygun, Hilmiye Deniz Ertugrul
dc.date.accessioned2020-12-01T12:09:04Z
dc.date.available2020-12-01T12:09:04Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractIn this study, a molecularly imprinted sensor technology is engineered to detect glucose in real blood samples by chronoimpedimetrically. the imprinting process of glucose (Glc) was carried out by electrochemical polymerization of aminophenylboronic acid (APBA) and pyrrole (Py) by performing cyclic voltammetry (CV). Afterwards, glucose molecule was removed from imprinted surface by 5 % acetic acid to reveal glucose imprinted cavities. Electrochemical Impedance Spectroscopy (EIS) was used to characterize sensor modification steps and glucose removal. Glucose monitoring process was carried out chronoimpedimetrically(CI) for the first time in real blood samples. Calibration curve was prepared between 20-800 mg/dL. the standard deviations of the 18 calibration curves R-2 were calculated as 0.9866 +/- 0.0066 to assess reproducibility. Recovery was calculated by using 105 mg/dL Glc Serum Sample, which was monitored by auto analyzer and into this sample 50 mg/dL Glc added and our sensor response was 147.92 +/- 2.43 mg/dL, 98.6 +/- 1.62 % (n=5). Non-imprinted (NIP) sensor gave no signal for the glucose concentration.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey(TuBTAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [2150218]en_US
dc.description.sponsorshipThis project was supported by the Scientific and Technological Research Council of Turkey(TuBTAK) project number 2150218.en_US
dc.identifier.doi10.1002/elan.201900537
dc.identifier.endpage229en_US
dc.identifier.issn1040-0397
dc.identifier.issn1521-4109
dc.identifier.issn1040-0397en_US
dc.identifier.issn1521-4109en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85074614165en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage226en_US
dc.identifier.urihttps://doi.org/10.1002/elan.201900537
dc.identifier.urihttps://hdl.handle.net/11454/63290
dc.identifier.volume32en_US
dc.identifier.wosWOS:000492166100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofElectroanalysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectglucoseen_US
dc.subjectsensoren_US
dc.subjectmolecular imprintingen_US
dc.subjectchronoimpedanceen_US
dc.subjectimpedanceen_US
dc.titleA Novel Chronoimpedimetric Glucose Sensor in Real Blood Samples Modified by Glucose-Imprinted Pyrrole-Aminophenylboronic Acid Modified Screen Printed Electrodeen_US
dc.typeArticleen_US

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