Effect of nifedipine on the collar-induced intimal thickening and vascular reactivity changes in rabbits
Küçük Resim Yok
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The positioning of a soft and nonocclusive silicon collar around the rabbit carotid artery induces intimal thickening and characteristic vascular reactivity changes. In the present study, we investigated whether the treatment with nifedipine, a dihydropyridine derivative calcium channel blocker (CCB) (40 mg/kg/day, p.o.), inhibit development of intimal thickening and accompanying vascular reactivity changes in this model. Neither intimal thickening nor vascular reactivity changes were effected by nifedipine treatment in this model.
Açıklama
Anahtar Kelimeler
Calcium channel bloker, Collar, Intimal tickening, Vascular reactivity
Kaynak
Acta Pharmaceutica Turcica
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
47
Sayı
3
