Evaluation of pyrethroid susceptibility in culex pipiens of Northern Izmir Province, Turkey
Küçük Resim Yok
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Tehran University of Medical Sciences
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Mosquitoes, being a nuisance species, are considered as one of the most important species in public health control programs due to their role as a vector in mosquito-borne diseases observed in humans and animals. We evaluated the susceptibility status of Culex pipiens collected from northern Izmir, Turkey in 2011-16. Methods: Mosquito larvae, collected from three different locations in northern İzmir, were reared in the laboratory. Adult susceptibility bioassays were performed using the WHO insecticide-impregnated papers including deltamethrin 0.05%, permethrin 0.75%, ?-cypermethrin 0.05% and cyfluthrin 0.15%. In addition, adult bioassays were performed after the pre-exposure to piperonyl butoxide (PBO) to determine the contribution of P450 detoxification enzymes to the phenotypic resistance. Results: In all of the three populations, high levels of resistance were observed (mortalities<63%) to all of the four pyrethroids. Different pyrethroids but with the same mode of action can exhibit significantly different phenotypic resistance in a single population. PBO bioassays also showed that P450 detoxification enzymes can have diverse effects on different pyrethroids. Conclusion: Using just one chemical in a class of insecticide can be misleading for resistance studies. © 2018 Tehran University of Medical Sciences. All rights reserved.
Açıklama
Anahtar Kelimeler
Bioassay, Culex pipiens, Insecticide resistance, PBO, Pyrethroids
Kaynak
Journal of Arthropod-Borne Diseases
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
12
Sayı
4
