Analysis of expressed genes in normal and tumoral mammary gland tissue of the terrier dog [Terrier köpeklerinin normal ve tümörlü meme bezi dokusunda eksprese edilen genlerin birincil analizi]

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dc.contributor.authorOzdemir Ozgenturk N.
dc.contributor.authorOmeroglu Ulu Z.
dc.contributor.authorUlu S.
dc.contributor.authorCelik M.
dc.contributor.authorTellioglu B.
dc.contributor.authorYildirim F.
dc.contributor.authorAkis Akad I.
dc.contributor.authorGurel A.
dc.contributor.authorUn C.
dc.contributor.authorOztabak K.O.
dc.date.accessioned2019-10-27T08:03:02Z
dc.date.available2019-10-27T08:03:02Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractMammary gland tumor is the most common type of tumor in female dogs. Data on genes that are involved in tumorigenesis and mechanism of tumor development are insufficient. Comparative studies have been conducted in order to see if tumorigenesis studies in the dog could be a model for human mammary gland tumors. In this study, we constructed two different cDNA libraries from mammary tissue, which were collected from a normal mammary tissue of a healthy Terrier dog and a tumoral mammary tissue of a sick dog. A total 2304 colonies which are randomly picked out from the two libraries were sequenced for developing a dog mammary gland ESTs collection. Raw EST data were analyzed with Phred/Phrap programs and readable EST sequences were assembled with the CAP3 program. All of EST sequences were grouped into 45 contig and 2203 singletons. Putative functions of all unique sequences were designated by NCBI BLAST based on gene homology and annotated by BLAST2GO. The results of this study are a very valuable resource for functional genome studies of the dogs. © 2018, Veteriner Fakultesi Dergisi. All rights reserved.en_US
dc.identifier.doi10.9775/kvfd.2017.18964
dc.identifier.endpage364en_US
dc.identifier.issn1300-6045
dc.identifier.issn1300-6045en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage357en_US
dc.identifier.urihttps://doi.org/10.9775/kvfd.2017.18964
dc.identifier.urihttps://hdl.handle.net/11454/25289
dc.identifier.volume24en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVeteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast canceren_US
dc.subjectcDNA libraryen_US
dc.subjectDogen_US
dc.subjectESTen_US
dc.subjectTerrieren_US
dc.titleAnalysis of expressed genes in normal and tumoral mammary gland tissue of the terrier dog [Terrier köpeklerinin normal ve tümörlü meme bezi dokusunda eksprese edilen genlerin birincil analizi]en_US
dc.typeArticleen_US

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