Bioinformatic Analysis

dc.authorscopusid6603393702
dc.authorscopusid57924592100
dc.authorscopusid57923958500
dc.contributor.authorÖtleş S.
dc.contributor.authorBakar B.
dc.contributor.authorTürköz B.K.
dc.date.accessioned2023-01-12T20:23:42Z
dc.date.available2023-01-12T20:23:42Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractBioinformatics has found many applications in molecular research and recently food sciences, including tools that are used in bioactive peptide research. These tools help predict the bioactivity potential of proteins, suitable enzymes for peptide release, and potential bioactive, allergenic, toxic, and sensory properties of the resulting peptides. Current databases have prediction tools based on hydrolysis patterns of various enzymes, which results in in silico hydrolysis of protein sequences. However, the tertiary structure of proteins is not taken into account in current hydrolysis predictors, which limits the accurate prediction of potential bioactive peptides. Structures of proteins and peptides can be obtained by experimental as well as bioinformatic methods. Structure of bioactive peptides can give valuable information on their function and can further be analyzed for dynamic intermolecular interactions using different approaches, such as molecular dynamics, docking, and quantitative structure–activity relationship. In this chapter, bioinformatic approaches used for prediction of bioactive peptides, their structures, and structure–function relationship will be reviewed with future perspectives on structure based bioactive peptide prediction. © 2022 selection and editorial matter, Leo M.L. Nollet and Semih Ötleş individual chapters, the contributors.en_US
dc.identifier.doi10.1201/9781003106524-20
dc.identifier.endpage345en_US
dc.identifier.isbn9781000551938; 9780367608538
dc.identifier.scopus2-s2.0-85139629969en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage321en_US
dc.identifier.urihttps://doi.org/10.1201/9781003106524-20
dc.identifier.urihttps://hdl.handle.net/11454/79752
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCRC Pressen_US
dc.relation.ispartofBioactive Peptides from Food: Sources, Analysis, and Functionsen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleBioinformatic Analysisen_US
dc.typeBook Chapteren_US

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