ANTIFUNGAL COTTON FABRIC VIA MOLECULAR ENCAPSULATION OF TERBINAFINE

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dc.contributor.authorErkan, Gokhan
dc.contributor.authorSariisik, Merih
dc.contributor.authorPazarlioglu, Nurdan Kasikara
dc.date.accessioned2019-10-27T22:13:59Z
dc.date.available2019-10-27T22:13:59Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractThe aim of the study was to investigate inclusion complex formation of terbinafine, an allylamine based antifungal pharmaceutical agent, by spray drying and kneading, and its grafting onto cotton fabric. Terbinafine was introduced in monochlorotriazine-beta-cyclodextrin in 3 different molar ratios. The products were obtained by spray drying and kneading. The products were analyzed by X-ray diffractometry, differential scanning calorimetry and FTIR spectroscopy. Terbinafine and monochlorotriazine-beta-cyclodextrin in 1:3 molar ratio presented evidence of inclusion complex formation by both spray drying and kneading methods. The inclusion complex was applied to 100% cotton fabric by the padding method. Then the fabric was subjected to different numbers of washing cycles. N percentage of the fabrics was determined by C, H, N, S elemental analysis to evaluate washing durability. Antifungal strength against Trichophyton rubrum was observed even after 15 washing cycles.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [MAG-104M265]en_US
dc.description.sponsorshipThis work was supported by The Scientific and Technological Research Council of Turkey (TUBITAK) under Grant No. MAG-104M265. We are grateful to Prof. Dr. Ufuk Yucel for his valuable assistance.en_US
dc.identifier.endpage760en_US
dc.identifier.issn0576-9787
dc.identifier.issn0576-9787en_US
dc.identifier.issue07.Augen_US
dc.identifier.startpage753en_US
dc.identifier.urihttps://hdl.handle.net/11454/49918
dc.identifier.volume48en_US
dc.identifier.wosWOS:000345192400017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofCellulose Chemistry and Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectterbinafineen_US
dc.subjectmonochlorotriazine-beta-cyclodextrinen_US
dc.subjectcotton fabricen_US
dc.subjectspray dryingen_US
dc.subjectkneadingen_US
dc.titleANTIFUNGAL COTTON FABRIC VIA MOLECULAR ENCAPSULATION OF TERBINAFINEen_US
dc.typeArticleen_US

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