Preparation and characterization of sodium lauroyl sarcosinate adsorbed on cetylpyridinium-montmorillonite as a possible antibacterial agent

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dc.contributor.authorYapar, Saadet
dc.contributor.authorAtes, Mustafa
dc.contributor.authorOzdemir, Gunseli
dc.date.accessioned2019-10-27T10:47:08Z
dc.date.available2019-10-27T10:47:08Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractAn organo-montmorillonite was synthesized to generate a two-level antibacterial agent. The material (Mt-CP-SR) was prepared through the adsorption of sodium lauroyl sarcosinate (SR) on montmorillonite modified with cetylpyridinium (Mt-CP) and its structure was characterized by conducting ATR-FTIR, XRD, and SEM analyses. The results of the ATR-FTIR analyses indicated that SR on the surface could be detected when its amount exceeded the CEC of the Mt. The XRD analyses revealed that the adsorption of CP and SR causes the separation of Mt layers into smaller stacks. The adsorption and desorption study of SR onto and from 0.7 CEC Mt-CP were investigated to determine the amount of SR adsorbed at varying initial SR concentrations and the amount of SR released when diluted with water. Around 140 mg of SR could be loaded on one gram of the Mt intercalated with 170 mg of CP. The results indicated that desorption of SR from the surface is gradual and SR and CP have strong interactions on the montmorillonite (Mt) surface. The antibacterial activity of the material was tested against E. coil, S. aureus, and P. aeruginosa. Additionally, the SR solutions and CP + SR solutions in equimolar ratios were subjected to antibacterial tests for comparison purposes. SR proved to be effective against all three bacteria and the MIC values were found as 75 mg/mL for E. coil, 37.5 mg/mL for S. aureus, and 300 mg/mL for P. aeruginosa. The MBC was 300 mg/mL for E. coil and S. aureus. The solutions of CP + SR mixtures were ineffective against P. aeruginosa, whereas, they were effective against S. aureus. The prepared Mt-CP-SR samples were found to be effective against S. aureus and E. coil. These results indicate that the material could be used in antibacterial liquid soaps, in toothpaste formulations, personal care products, and topical applications against acne, and wounds without any negative contribution to the physico-chemical and detergency properties of the materials.en_US
dc.identifier.doi10.1016/j.clay.2017.08.025
dc.identifier.endpage22en_US
dc.identifier.issn0169-1317
dc.identifier.issn1872-9053
dc.identifier.issn0169-1317en_US
dc.identifier.issn1872-9053en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage16en_US
dc.identifier.urihttps://doi.org/10.1016/j.clay.2017.08.025
dc.identifier.urihttps://hdl.handle.net/11454/31383
dc.identifier.volume150en_US
dc.identifier.wosWOS:000414820500003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofApplied Clay Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOrgano-montmorilloniteen_US
dc.subjectSodium lauroyl sarcosinateen_US
dc.subjectCetylpyridinium chlorideen_US
dc.subjectAdsorption-desorptionen_US
dc.subjectAntibacterial activityen_US
dc.titlePreparation and characterization of sodium lauroyl sarcosinate adsorbed on cetylpyridinium-montmorillonite as a possible antibacterial agenten_US
dc.typeArticleen_US

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