Effectiveness of Sentinel Lymph Node Biopsy with Pre-epiglottic Tc99 Injection

Basit Öğe Kaydı
dc.contributor.authorAkyildiz, S.
dc.contributor.authorKaya, I.
dc.contributor.authorOzturk, K.
dc.contributor.authorTurhal, G.
dc.contributor.authorYavuzer, A.
dc.date.accessioned2019-10-27T11:19:42Z
dc.date.available2019-10-27T11:19:42Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Despite ongoing research and previous successful reports, sentinel lymph node biopsy (SLNB) has not gained widespread use in the management of the neck in laryngeal carcinoma. The aim was to assess the effectiveness of the SLNB technique in laryngeal carcinoma with the novel percutaneous pre-epiglottic radiotracer injection technique. Methodology: Twenty-seven SLNBs of 18 patients with laryngeal squamous cell carcinoma were retrospectively reviewed. T1-3 stage laryngeal cancer patients, either originating or involving the supraglottic region, with no clinically or radiologically proven neck metastasis, were selected for radionuclide injection. All patients required selective neck dissection for their primary tumour. Tc99m-labelled nanocolloid was injected into the pre-epiglottic area. Sentinel lymph nodes (SLNs) were localized and excised on the day of surgery using static lymphoscintigraphy images and a gamma probe. Results: All of the malignant nodes were detected with the SLNB technique and definite pathology results. After considering the definite pathology results with the use of serial step sectioning technique accuracy, negative predictive value, positive predictive value, sensitivity and specificity rates were all found to be 100%. Based on the frozen sections, there were five false negative results in the study. The positive and negative predictive values of the technique was 100% and 76.2%, respectively, regarding frozen sections. Based on the frozen section data, the sensitivity of the SLNB technique was 68.8% and specificity was 100%. Conclusions: Pre-epiglottic percutaneous radiotracer injection is a reliable and safe technique to detect SLNs in laryngeal carcinoma. However the results of the frozen section analysis yielded a lower accuracy rate.en_US
dc.identifier.endpage210en_US
dc.identifier.issn1781-782X
dc.identifier.issn1781-782Xen_US
dc.identifier.issue3en_US
dc.identifier.startpage205en_US
dc.identifier.urihttps://hdl.handle.net/11454/32820
dc.identifier.volume13en_US
dc.identifier.wosWOS:000414402300006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherRoyal Belgian Soc Ear, Nose, Throat, Head & Neck Surgeryen_US
dc.relation.ispartofB-Enten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSentinel lymph nodeen_US
dc.subjectneck dissectionen_US
dc.subjectlaryngeal canceren_US
dc.subjectpre-epiglottic spaceen_US
dc.subjecthead and neck canceren_US
dc.titleEffectiveness of Sentinel Lymph Node Biopsy with Pre-epiglottic Tc99 Injectionen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu