Development of a solid phase microextraction gas chromatography tandem mass spectrometry method for the analysis of UV filters

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dc.authoridyücel, cemile/0000-0003-0375-365X
dc.authoridErtas, Fatma Nil/0000-0001-8982-9621
dc.contributor.authorYucel, Cemile
dc.contributor.authorErtas, Hasan
dc.contributor.authorErtas, Fatma Nil
dc.contributor.authorKarapinar, Ilgi
dc.date.accessioned2024-08-31T07:50:37Z
dc.date.available2024-08-31T07:50:37Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: UV filters are endocrine disrupting chemicals that have significant effects on biota and human health, even at trace levels. Numerous studies have been conducted to determine its residues in surface waters. Since their main distribution route to the environment is wastewater treatment plants, rapid, sensitive and environmentally friendly methods are required to be developed for their detection in such a complex matrix. Results: A method based on headspace solid phase microextraction followed by gas chromatography-tandem mass spectrometric detection (HS/SPME-GC-MS/MS) was developed for the online extraction of nine UV filter compounds belonging to different chemical groups. The parameters affecting the extraction efficiency were scanned using Plackett Burman (P -B) design and then, significant parameters were optimized using Central Composite design (CCD) as follows; 10 mL of sample volume added NaCl to be 20 % (w/v) is equilibrated at 88.0 degrees C and extraction is carried out in headspace mode with a polyacrylate (PA) fiber for 20 min. The method was validated by using wastewater samples and the LOD values were calculated in the range of 4.21-12.0 ng L-1, which is quite satisfactory for such complex matrices. Recovery percentages for the wastewater samples spiked with sub ppb levels were found as 89.4-115 %. In addition, the analysis time was substantially shortened due to the lack of derivatization. Significance: This study describes the development of a HS/SPME method for rapid, greener, and yet more sensitive determination of the UV filters in wastewater samples.en_US
dc.identifier.doi10.1016/j.microc.2024.110247
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85186530713en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.microc.2024.110247
dc.identifier.urihttps://hdl.handle.net/11454/105303
dc.identifier.volume200en_US
dc.identifier.wosWOS:001203712700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMicrochemical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240831_Uen_US
dc.subjectUv Filtersen_US
dc.subjectWastewateren_US
dc.subjectOn -Line Solid Phase Microextractionen_US
dc.subjectCentral Composite Designen_US
dc.subjectPlackett Burman Designen_US
dc.titleDevelopment of a solid phase microextraction gas chromatography tandem mass spectrometry method for the analysis of UV filtersen_US
dc.typeArticleen_US

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