Synthesis and characterization of polymethacrylamide having gabapentin moieties
Küçük Resim Yok
Tarih
2007
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Polymer Research Center Iran
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The synthesis and radical polymerization of methacrylamide having Gabapentin (GBP) moieties were examined. The monomer was prepared by reaction of methyl-1-aminomethyl-1-cyclohexane acetic acid salt with methacryloyl chloride in presence of triethylamine in moderate yields. Radical polymerizations of the monomer were carried out in presence of AlBN (3 mol%) in DMF in moderate yield. The thermal behaviour of the polymers was investigated by thermogravimetric analysis (TGA) and differential scanning calorimeter (DSC) to determine the thermal degradation pattern and glass transition temperature (T(g)). The resulting polymer showed a thermal stability up to similar to 400 degrees C. We found the molecular weight of the polymer to be 4340 g/mol (M(w)/M(n)=1.33) and poly[N-[(1-1-methoxyformoyl-1'-methyl) cyclohexylmethyl] methacrylamide] (poly[MFCHM]) were soluble in common solvents.
Açıklama
Anahtar Kelimeler
Gabapentin, polymethacrylamide, radical polymerization, thermogravimetric analysis, differential scanning calorimeter
Kaynak
Iranian Polymer Journal
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
16
Sayı
11
