The distance factor and effect of I.N.H. in fracture healing

dc.contributor.authorSoydan S.
dc.contributor.authorAksu Y.
dc.date.accessioned2019-10-27T08:00:13Z
dc.date.available2019-10-27T08:00:13Z
dc.date.issued1974
dc.departmentEge Üniversitesien_US
dc.description.abstractIn order to investigate the role of distance factor and the effect of I.N.H. on fracture healing, 48 femoral bones from 12 day old chicken embryos were used. The bones were cultivated in 8 Petri dishes. The distance between corresponding fracture surfaces was 1 mm in the first 2 Petri dishes. One of these 2 dishes contained Medium 199, and the other 1.75.?/cm3 I.N.H. added Medium 199. One Petri dish out of 8 contained 6 bones with a distance of 2 mm between corresponding fracture surfaces; the bones were cultivated in normal medium. In 2 Petri dishes the bones were cultivated in normal medium. In 2 Petri dishes the distance between corresponding bone surfaces was 3 mm; one dish contained the normal, and the other the I.N.H. added medium. One Petri dish was used for 4 mm distance, and 2 Petri dishes were used for 5 mm distance. One dish of the latter group contained the normal, and the other the I.N.H. added medium. The bones were cultivated for 11 days, changing and renewing the medium every 2 days. The cultivated bones were observed daily and afterwards examined with the phase contrast microscope and also histologically. The histologic sections were stained with H+E, and also with P.A.S., elastic and reticulum stains, Van Gieson and Masson's trichrome stains. The shorter the distance between corresponding fracture surfaces, the better, quicker and more complete was the fracture healing. As the distance increased, the chance of fracture healing decreased and also the presence of the osteoid substance. At the same time, in such cases the connection between corresponding fracture surfaces was too thin. Along with the distance factor, I.N.H. played a positive role in fracture healing. Particularly in the 3 mm distance cases, the connection between fracture surfaces was thicker, and also the number of healed bones was higher. The presence of osteoid substance in the healing site and also in parts to the corresponding fracture surfaces, especially in the 5 mm distance bones, was an interesting observation.en_US
dc.identifier.endpage95en_US
dc.identifier.issn0304-4939
dc.identifier.issn0304-4939en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage81en_US
dc.identifier.urihttps://hdl.handle.net/11454/24645
dc.identifier.volume3en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofAegean Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThe distance factor and effect of I.N.H. in fracture healingen_US
dc.typeArticleen_US

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