Evaluation of quality of life of nasopharyngeal carcinoma patients treated in a single institution
Küçük Resim Yok
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Drunpp-Sarajevo
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aim: To evaluate the Quality of Life (QOL) of patients with nasopharyngeal carcinoma (NPC) treated in the Izmir Oncology Centre (IOC) as part of a retrospective survival analysis study. Methods: 31 patients with Nasopharyngeal Cancer (NPC) and treated in the Izmir Oncology Centre between April 2001 and January 2008 were included in the study. Basic demographic and clinical data were extracted from the patients files. Histopathological evaluation was done according to WHO criteria, and clinical staging was done according to the American Joint Commission on Cancer (AJCC 1997). Radiotherapy was given by standard technique with a routine dose of 70Gy to the primary tumour and metastatic lymph nodes, and in most cases this was combined with chemotherapy. All the patients completed the European Organization for Research and Treatment of Cancer Core QOL Questionnaire (EORTC QLQ-C30) and head & neck specific module (QLQ H&N-35). Both had been translated into Turkish and validated in a previous study. Results: The overall median follow up time was 55 months (range, 12 month-90 month). The mean global health score for QLQ-C30 (ver. 3.0) was high (63.4), and the functional scale scores were higher. The lowest functional scale score was the physical functioning score (83.9). The highest functional scale scores were for cognitive functioning and social functioning (98.9 and 95.7) respectively. The highest adverse symptom scores were for insomnia (26.9) and fatigue (24.0). None of the patients complained of diarrhoea. No statistical significance from normal was found for physical functioning, role functioning, emotional functioning, cognitive functioning for gender, treatment, histopathology, and staging. These satisfactory scores, in conjunction with a high 5 year survival rate of 55%, support the policy of the Izmir Oncology Centre in the use of radiotherapy combined with chemotherapy in the treatment of NPC. In conclusion the QOL of cancer patients is an important criterion in evaluating the outcome of the treatment and should be integrated into the programmes of treatment centres.
Açıklama
Anahtar Kelimeler
Quality of life, Nasopharyngeal carcinoma, Questionnaire
Kaynak
Healthmed
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
6
Sayı
4
