Outcome of joint functions in hemophilic patients: A twelve year retrospective study
Küçük Resim Yok
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In hemophilic patients, recurrent intra-articular bleeding results in hemophilic arthropathy. The frequently affected joints are knee, elbow, and ankle. Prevention of recurrent joint bleedings is of great significance in avoiding hemophilic arthropathy. Bleedings may occur as a result of minor traumas or spontaneously in severe hemophilic patients. In this study, data belonging to 31 hemophilic patients were analyzed after a 12-year retrospective observation. Joints of knee, elbow, and ankle were assessed with Gilbert score and swelling, atrophy, axial deformity, crepitus, range of motion, and flexion contracture were assessed in terms of instability. Patients were grouped based on the severity of hemophilia. Severe hemophiliacs were grouped depending on whether they received long term prophylaxis or on-demand therapy. As a conclusion, it was observed that joint assessment results of severe hemophiliacs who received on-demand therapy were rather poor compared to those of mild or moderate hemophiliacs. Joint assessment results obtained from hemophilia patients who received prophylaxis, on the other hand, were almost as good as those of mild hemophiliacs. Based on swelling, atrophy, axial deformity, crepitus, flexion contracture and loss of full range of motion, there was a significant difference between the on-demand and prophylaxis groups in severe hemophiliacs (p< 0.05). In the on-demand group there was a significant difference between the baseline and final evaluations based on all parameters (p< 0.05). Consequently, it was determined that prophylactic treatment has a crucial role in the prevention of arthropathy in severe hemophiliacs. Copyright © 2010 by Türk Tibbi Rehabilitasyon Kurumu Dernegi.
Açıklama
Anahtar Kelimeler
Gilbert score, Hemophilia, Joint assessment, Prophylaxis
Kaynak
Journal of Rheumatology and Medical Rehabilitation
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
21
Sayı
2
