Successful Immunoglobulin Replacement with Subcutaneous Immunoglobulin Therapy in a Patient with Primary Intestinal Lymphangiectasia

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dc.contributor.authorAytekin, Gokhan
dc.contributor.authorColkesen, Fatih
dc.contributor.authorArdeniz, Omur
dc.contributor.authorCaliskaner, Zafer
dc.date.accessioned2019-10-27T09:48:17Z
dc.date.available2019-10-27T09:48:17Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractPrimary intestinal lymphangiectasia is a rare disorder which characterized by unpaired small intestinal lymph drainage. There is loss of proteins from dilated lymphatic channels located in the mucosa, submucosa or subserosa which is results with loss of gammaglobulins and lymphocytes, leading to impaired humoral and cellular immunity. Herein, we present a 61-year-old patient with immunodeficiency secondary to Primary intestinal lymphangiectasia (PIL), in whom we could attain effective and stable IgG levels only by subcutaneous IgG replacement rather than intravenous IgG. Our experience suggests that Subcutaneous Immunoglobulin (SCIG) replacement resulted in more stable levels of IgG in the presented patient with PIL. We concluded that SCIG should be the preferred route of immunoglobulin replacement therapy in secondary hypogammaglobulinemia due to protein losing enteropathy, especially in PIL.en_US
dc.identifier.doi10.21911/aai.442
dc.identifier.endpage60en_US
dc.identifier.issn1308-9234
dc.identifier.issn1308-9234en_US
dc.identifier.issue1en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://doi.org/10.21911/aai.442
dc.identifier.urihttps://hdl.handle.net/11454/29508
dc.identifier.volume17en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBilimsel Tip Yayinevien_US
dc.relation.ispartofAstim Allerji Immunolojien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPrimary Intestinal Lymphangiectasiaen_US
dc.subjectsecondary hypoglobulinemiaen_US
dc.subjectsubcutaneous immunoglobulinen_US
dc.titleSuccessful Immunoglobulin Replacement with Subcutaneous Immunoglobulin Therapy in a Patient with Primary Intestinal Lymphangiectasiaen_US
dc.typeArticleen_US

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