Investigation of the adherence and proliferation characteristics of SH-SY5Y neuron model cells on graphene foam surfaces
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Graphene is a promising material for production of biocompatible surfaces with suitable physicochemical properties for effective adhesion, proliferation and differentiation of nerve cells. In this study, 3-dimensional (3D) graphene foam was synthesized via chemical vapour deposition method, and it was aimed to observe the effects of graphene foam scaffolds on SH-SY5Y dopaminergic neuron model cells before applying to clinics. Raman spectroscopy, XRD and SEM analyses were performed to characterize the graphene foam. Viability of SH-SY5Y cells cultured on graphene foam scaffolds was analysed on days 1, 4 and 7 by MTT. Furthermore, cell morphology was determined by fluorescence staining of the actin cytoskeleton. © 2019 Elsevier Ltd. All rights reserved.