EFFECTIVENESS OF USING PRE-HOSPITAL ASPIRIN AND ANTI-INFLAMMATORY DRUGS ON MORTALITY AND MORBIDITY IN ACUTE RESPIRATORY DISTRESS SYNDROME PATIENTS

dc.contributor.authorSahin, Ayca Sultan
dc.contributor.authorDerbent, Abdurrahim
dc.contributor.authorSalihoglu, Ece
dc.date.accessioned2020-12-01T12:09:21Z
dc.date.available2020-12-01T12:09:21Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.descriptionSalihoglu, Ece/0000-0002-7170-7877en_US
dc.description.abstractObjective: in this study, we aimed to investigate the efficacy of pre-hospital use of aspirin and anti-inflammatory agents in patients with Acute Respiratory Distress Syndrome (ARDS) and mortality in critically ill patients, by retrospectively screening ARDS patients treated in intensive care unit (ICU). Material and Method: Demographic data, duration time of ICU, intensive care unit Apache-II score, presence of comorbidity and mortality, procalcitonin and C-Reactive Protein (CRP) levels. neutrophil/lymphocyte (N/L) rates, Berlin Criteria, the use of aspirin and anti-inflammatory drugs, and the presence of infection findings from, the files of ARDS patients followed from January 2016 to January 2017. Results: Forty of the 43 ARDS patients were included in the study. Eighteen patients (90%) had worsening in the first week, 14 (70%) had chest X-ray pathology, 15 had (75%) pulmonary edema and 12 had (60%) needed oxygen. Statistically significant difference was found in these Berlin Criteria (p<0.05). There were significant differences between last procalcitonin values, the first and last CRP N/L ratios values, hospitalization times and APACHE II scores (p<0.05). There were no statistically significant differences between first and last leukocyte levels (p >= 0.05). Conclusion: Pre-hospital aspirin and anti-inflammatory drugs seemed to decrease morbidity in terms of Berlin. Criteria but there were no significant differences between mortality in ARDS patients in intensive care unit. However, further research is needed to confirm the results.en_US
dc.identifier.endpage15en_US
dc.identifier.issn1305-2381
dc.identifier.issn1305-2381en_US
dc.identifier.issue3en_US
dc.identifier.startpage12en_US
dc.identifier.urihttps://hdl.handle.net/11454/63418
dc.identifier.volume15en_US
dc.identifier.wosWOS:000508954100002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherNobel Ilacen_US
dc.relation.ispartofNobel Medicusen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute respiratory distress syndromeen_US
dc.subjectaspirinen_US
dc.subjectanti-inflammatory drugen_US
dc.titleEFFECTIVENESS OF USING PRE-HOSPITAL ASPIRIN AND ANTI-INFLAMMATORY DRUGS ON MORTALITY AND MORBIDITY IN ACUTE RESPIRATORY DISTRESS SYNDROME PATIENTSen_US
dc.typeArticleen_US

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