Could we Predict Respiratory Failure in Amyotrophic Lateral Sclerosis?

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dc.authorscopusid57211375635
dc.authorscopusid51663107200
dc.authorscopusid7801410578
dc.authorscopusid7004471414
dc.authorscopusid6507331366
dc.contributor.authorAkkoc, Ceren Cetin
dc.contributor.authorAykac, Seyma
dc.contributor.authorBademkiran, Fikret
dc.contributor.authorAydogdu, Ibrahim
dc.contributor.authorTasbakan, Sezai
dc.date.accessioned2023-01-12T20:16:24Z
dc.date.available2023-01-12T20:16:24Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractIntroduction: Respiratory complications are important in the prognosis of amyotrophic lateral sclerosis (ALS). The aim of this study was to determine the electrophysiological findings that may predict respiratory failure. Methods: According to the Awaji electrodiagnostic criteria, 30 patients with ALS who were diagnosed with definite or probable ALS without respiratory failure were included in the study. Nerve conduction studies, needle electromyography (EMG), and single-breath count tests were performed in all patients. In addition, the pulmonary function tests, swallowing EMG, and arterial blood gas analysis of the patients were recorded and evaluated. The patients were followed until respiratory failure developed. Results: As a result of 18 months of follow-up, 26 of 30 patients developed respiratory failure. When the contribution of the accessory respiratory muscles to the respiratory effort before the development of respiratory failure was evaluated clinically and electrophysiologically, it was observed that the most common muscles involved in the respiratory effort were sternocleidomastoid (SCM), trapezius, and rectus abdominis. Before the development of respiratory failure, the latest neurogenic EMG findings were seen in the SCM (50% cases), trapezius (20% cases), and thoracic paraspinal muscles (17% of cases), respectively. It was thought that this finding could be an important early electrophysiologic marker in predicting the development of respiratory failure in ALS cases. Conclusions: To sum up, the presence of neurogenic changes in certain muscles in needle EMG and demonstration of the contribution of certain accessory respiratory muscles in respiration can be used as an electrophysiological marker to predict the development of respiratory failure.en_US
dc.identifier.doi10.4103/nsn.nsn_210_21
dc.identifier.endpage13en_US
dc.identifier.issn2636-865X
dc.identifier.issn2636-865Xen_US
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85128370599en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage8en_US
dc.identifier.urihttps://doi.org/10.4103/nsn.nsn_210_21
dc.identifier.urihttps://hdl.handle.net/11454/78707
dc.identifier.volume39en_US
dc.identifier.wosWOS:000789612600002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNeurological Sciences And Neurophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmyotrophic lateral sclerosisen_US
dc.subjectearly electrophysiologic markeren_US
dc.subjectelectromyographyen_US
dc.subjectelectrophysiological evaluationen_US
dc.subjectrespiratory failureen_US
dc.subjectDiagnosisen_US
dc.subjectCriteriaen_US
dc.subjectAssociationen_US
dc.subjectDenervationen_US
dc.subjectAbdominisen_US
dc.titleCould we Predict Respiratory Failure in Amyotrophic Lateral Sclerosis?en_US
dc.typeArticleen_US

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