Synthesis, characterization and the photodynamic activity against some gram negative and positive bacteria of novel subphthalocyanine derivative

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dc.contributor.authorInce M.
dc.contributor.authorSeven Ö.
dc.contributor.authorDindar B.
dc.date.accessioned2019-10-26T21:36:54Z
dc.date.available2019-10-26T21:36:54Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractA specific tris(3,5-di-tert-butyl-4-hydroxyphenyl)Subphthalocyaninehydroxyde (SubPc-1) derivative was synthesized and the structure of SubPc-1 was confirmed by UV-Vis, Fluorescence, FTIR, 1H NMR, 13C NMR and MALDI-TOF-MS spectroscopy. Its thermal stability and photostability tests were checked by using TGA and solar simulator, respectively. In addition, the singlet oxygen produced capacity of amphiphilic SubPc-1 was determined for PDT studies. Besides, the photodynamic activity of this novel product against some of gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and gram positive bacteria (Staphylococus aureus, Enterococcus faecalis) has been investigated by using a xenon lamp which emits light in the ultravioletvisible region and is simulated for solar light as the illumination source. It was determined that the peripheral hydrophilic groups provided great opportunities in inactivation and solubility studies. This new amphiphilic macromolecule was especially found as an effective photosensitizer against gram positive bacteria in PDT, in particular.en_US
dc.identifier.endpage10en_US
dc.identifier.issn1303-9709
dc.identifier.issn1303-9709en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://hdl.handle.net/11454/18032
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofGazi University Journal of Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBacteriaen_US
dc.subjectBiological activityen_US
dc.subjectPhotodynamic inactivationen_US
dc.subjectPhotosensitizeren_US
dc.subjectSubphthalocyanineen_US
dc.titleSynthesis, characterization and the photodynamic activity against some gram negative and positive bacteria of novel subphthalocyanine derivativeen_US
dc.typeArticleen_US

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