An overview of risk factors for diabetic foot amputation: An observational, single-centre, retrospective cohort study

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dc.authorscopusid58246684600
dc.authorscopusid58247520300
dc.authorscopusid35574673900
dc.authorscopusid6505803191
dc.contributor.authorYuzuguldu, B.
dc.contributor.authorZengin, B.
dc.contributor.authorSimsir, I.Y.
dc.contributor.authorCetinkalp, S.
dc.date.accessioned2024-08-25T18:47:47Z
dc.date.available2024-08-25T18:47:47Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: Not only are early detection and treatment of diabetic foot ulcers important, but also acknowledging potential risk factors for amputation gives clinicians a considerable advantage in preventing amputations. Amputations impact both healthcare services and the physical and mental health of patients. This study aimed to investigate the risk factors for amputation in patients with diabetic foot ulcers. Methods: The sample for this study was patients with diabetic foot ulcers who were treated by the diabetic foot council at our hospital between 2005 and 2020. A total of 32 risk factors for amputation were identified and investigated among 518 patients. Results: Our univariate analysis showed that 24 of 32 defined risk factors were statistically significant. In the multivariate analysis using the Cox regression model, seven risk factors remained statistically significant. The risk factors most significantly associated with amputation were Wagner grading, abnormal peripheral arteries, hypertension, high thrombocyte levels, low haematocrit levels, hypercholesterolaemia and male sex, respectively. The most common cause of death in patients with diabetes who have undergone amputation is cardiovascular disease, followed by sepsis. Conclusion: To enable optimum treatment of patients with diabetic foot ulcers it is important for physicians to be aware of the amputation risk factors, and thus avoid amputations. Correcting risk factors, using suitable footwear and routinely inspecting feet are crucial factors for preventing amputations in patients with diabetic foot ulcers. © Touch Medical Media 2023.en_US
dc.identifier.doi10.17925/EE.2023.19.1.85
dc.identifier.endpage93en_US
dc.identifier.issn1758-3772
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85164695249en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage85en_US
dc.identifier.urihttps://doi.org/10.17925/EE.2023.19.1.85
dc.identifier.urihttps://hdl.handle.net/11454/102035
dc.identifier.volume19en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTouch Briefingsen_US
dc.relation.ispartofEuropean Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectAmputationen_US
dc.subjectAtherosclerosisen_US
dc.subjectDiabetic foot ulceren_US
dc.subjectHaematocriten_US
dc.subjectHypertensionen_US
dc.subjectPeripheral arterial diseaseen_US
dc.subjectSepsisen_US
dc.subjectThrombocytesen_US
dc.subjectWagner gradingen_US
dc.titleAn overview of risk factors for diabetic foot amputation: An observational, single-centre, retrospective cohort studyen_US
dc.typeArticleen_US

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