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Öğe Changes on some quality characteristics of fermented soy milk beverage with added apple juice(Academic Press, 2015) Içier F.; Gündüz G.T.; Yilmaz B.; Memeli Z.The fermented soy milk beverage with added apple juice was produced by using Lactobacillus acidophilus. The numbers of L.acidophilus, rheological properties, acidity and pH values were determined both after the production and during the storage period of 21 days at 4°C. In addition, sensory analyses of the beverages were done. The flow behavior of beverage was assessed by using three different rheological models, namely: Power Law, Herschel Bulkley and Vocadlo models. Vocadlo model was selected as the best model fitting the experimental data. The beverage was found to be a pseudoplastic fluid having the shear thinning nature. The results showed that L.acidophilus had good growth and viability in the beverage with or without apple juice. L.acidophilus counts were in the range of 8.73-9.11 log cfu/g after storage at 4°C for 21 days, thus they met required number of viable bacteria for probiotic functional food. Results revealed that this beverage could be a good vehicle to deliver probiotic microorganisms to consumers and carry a potential to become a commercial product. It is thought that the results of this study could provide valuable information for the design of pumping systems for the fermented soy milk beverages. © 2015 Elsevier Ltd.Öğe Chronic pain following spine surgery [Omurga cerrahisi sonrasi kronik agri](2012) Derbent A.; Yilmaz B.; Uyar M.There has been an increasing trends in the procedures of spine surgery in recent years. Postoperative chronic pain in spine surgery can be caused by damage or instability of spinal column; pressure on nerves or segment of spinal cord; or can be due to long lasting nociception caused by inflammation, infection or tumour. Pain that lasts longer than 3-6 months after surgery can be define as postoperative chronic pain. The incidence of postoperative chronic pain after surgical procedures, was between 10-50%. Coping with any type of chronic pain is quite difficult. Chronic postoperative pain can be treated with: NSAIDs, paracetamol, opioids, anticonvulsants and invasive technics such as nerve blocs, central blocs.Öğe E-commerce entrepreneurship and e-marketing in leather industry(Deri Teknologlari, Teknisyenleri ve Kimyacilari Dernegi, 2013) Yamamoto G.T.; Bayramoglu E.E.; Yilmaz B.; Şekero?lu Ö.This study tries to outline the benefits that can be provided by modern information technologies through the employment of electronic commerce methods to accelerate the development of Turkish Leather industry from the perspective of complying with the developing information society mainly for the development of marketing strategies and to bring the industry to the place it deserves in the overall world. The study further considers drawing an e-marketing road map in future plans.Leather industry is influenced by the economic crisis in the world as much as and even more than other industries as it is a labor-intensive industry which produces high value added products by using bovine and ovine hide and skin as the raw material input. Consequently, the leather industry reached another milestone together with the latest crisis that affected the entire world. Especially the countries that experience the distress of being depended to a single market such as Turkey endeavor for opening to more dynamic markets and also for increasing their production and promotion activities in the targeted markets. They have begun to attach more importance to branding and promotion issues. It is a fact that the efforts realized in this regard are mostly towards catching up with innovations and cutting edge technologies and in this context, e-commerce entrepreneurship is dwelled upon.The issues such as the transformation of the leather businesses to automation during the production process, and migration of certain company and product promotions to internet via computers also pave the way for e-commerce ventures. Besides, leather industry cannot be considered as isolated from the development of the information technologies industry which rapidly continues its growth. Moreover, as e-commerce gradually evolves into a more influential form both for domestic and global markets from the outlook of both supply and sales, one would clearly understand that the leather industry should very urgently take actions in this regard.Öğe In Vitro/In Vivo Evaluation of Radiolabeled [99mTc(CO)3]+-Hydroxyurea and Fluorescein Isothiocyanate-Hydroxyurea(Mary Ann Liebert Inc., 2016) Yilmaz B.; Teksoz S.; Kilcar A.Y.; Ucar E.; Ichedef C.; Medine E.I.; Ari K.The aim of current study is to examine hydroxyurea (HU), which is an antineoplastic drug used for the treatment of leukemia, sickle-cell disease, HIV, psoriasis, thrombocythemia, and various neoplastic diseases in two aspects. The active ingredient hydroxyurea was obtained by purification of the capsule form drug, commercially named as HYDREA. Then, [99mTc(CO)3]+core radiolabeling with HU was performed as first aspect. Quality control studies of 99mTc(CO)3-HU complex were performed by thin-layer radiochromatography and high-performance liquid radiochromatography methods. The results demonstrated that the radiolabeling yield was quite high (98.43% ± 2.29%). Also, 99mTc(CO)3-HU complex has good stability during the 24-hour period. Biological behavior of 99mTc(CO)3-HU complex is evaluated by biodistribution studies on Wistar Albino rats. Fluorescein isothiocyanate (FITC) labeling of HU was performed as second aspect. Fluorometric evaluation of binding efficacy and fluorescence imaging studies on MCF7 and Hela cell lines were carried out. It was thought that the knowledge achieved in this study would contribute to using 99mTc(CO)3-HU complex as an imaging agent, which inhibits the DNA synthesis selectively, by inhibiting ribonucleotide reductase enzyme. It was observed that FITC-HU has noteworthy incorporation on both cell lines. © Copyright 2016, Mary Ann Liebert, Inc. 2016.Öğe Indications for referral of Turner's syndrome cases diagnosed prenatally(2005) Yilmaz B.; Özkınay F.; Ercal D.; Sagol S.; Kanit H.; Kirayoglu H.; Özkınay, CihangirWe performed a retrospective study of 17 Turner's syndrome (TS) cases who were diagnosed prenatally in our Genetic Diagnostic Centre, Alsancak-Izmir, Turkey, during the period 2000-2005. The indications for prenatal diagnosis, ultra-sonographic findings and demographic data of the mothers were evaluated from patient records. The most frequent indications for prenatal diagnostic intervention were cystic hygroma (6/17) and hydrops fetalis (4/17). Other indications were advanced maternal age, abnormal triple test [alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (Estriol)] levels in the diagnosis of Down's syndrome and fetal growth retardation. A 45,X non-mosaic karyotype (14/17) was detected in 14 of these cases, while three showed mosaicism with the following karyotypes: 45,XO/46,XX, 45,XO/46,XY and 45,XO/46,X,del (X)(q21;qter), respectively.Öğe Intermittent catheterization in patients with traumatic spinal cord injury: Obstacles, worries, level of satisfaction(Nature Publishing Group, 2014) Yilmaz B.; Akkoç Y.; Alaca R.; Erhan B.; Gündüz B.; Yildiz N.; Gök H.; Köklü K.; Çinar E.; Alemdaro?lu E.; Ersöz M.; Karapolat H.; Demir Y.; Bardak A.N.; Turna I.; Çatalbaş N.; Güneş S.; Tunç H.Objectives: The aim of this study is to examine the obstacles in people with traumatic spinal cord injury (SCI) face performing intermittent catheterization (IC), also their worries and level of satisfaction. Methods: Two hundred sixty-nine patients performing IC for at least 3 months were asked to fill-out a questionnaire about their opinions on IC. Results: In total, 69.5% of patients performed IC themselves, 10.4% had performed by their mothers, 7.8% by another caregiver and 7.4% by their spouse. For the 72 (26%) patients unable to apply IC, reasons were insufficient hand function (56.1%), being unable to sit appropriately (35.4%) and spasticity (8.5%). In all, 70% of male patients had insufficient hand function, 20% could not sit and 10% had spasticity while 56.3% of female patients could not sit, 37.5% had insufficient hand function and 63% had spasticity. Difference between sexes was found to be statistically significant (P<0.05). Worries patients had when starting IC were fear of being dependent on IC (50.2%), accidentally injuring self (43.8%), embarrassment (43.2%), causing an infection (40.2%), bleeding (32.7%), fear of feeling pain (30.2%) and hygiene (24.7%). More women felt embarrassment; other items were similar in both sexes. In all, 46.9% of patients had urinary incontinence in intervals. Conclusion: In total, 69.5% of patients performed IC themselves. Men's most common obstacle was insufficient hand function while women's was being unable to sit appropriately. Patients' most common worries were being dependent on IC for life. In all, 46.9% had incontinence in intervals; 47.9% said IC improved their life quality; and 97.4% preferred IC over continuous catheterization. © 2014 International Spinal Cord Society All rights reserved.Öğe Investigation on the effects of various waste extracts on free formaldehyde in leather(2011) Eke Bayramoglu E.; Önem E.; Yorgancioglu A.; Yilmaz B.Due to the some chemical substances used in leather manufacturing, free formaldehyde is released in finished leathers and made serious problems for tanners. This situation causes the firms not to get Eco-Leather label and great problems are experienced about leather sales especially in recent years because natural and ecological products are in fashion. This study aims to reduce the free formaldehyde amount in leather by using various plant extracts (hazelnut shells, thyme, olive shoots, lavandula, ivy, christ's thorn seed), which are obtained from agricultural wastes, during retanning stage of leather processing. The analyses have been conducted with HPLC device according to IUC 19 (ISO TS 17226) method. According to the results; the extracts from hazelnut shells, thyme and olive shoots reduced the free formaldehyde amount on the leather by 35.49%, 33.86%, and 24.03% respectively. Color measurements on all finished leathers have been conducted with Konica Minolta CM-3600d brand spectrophotometer, light fastness analyses with ATLAS-XENOTEST ALPHA+ test instrument and according to ISO 105-B02 standard's method. The results showed that the plant extracts impacting formaldehyde considerably also improved the light fastness of the leather samples for a certain extent.Öğe Postoperative visual impairment after spinal fusion surgery(SAGE Publications Ltd, 2012) Karakoç Ö.; Derbent A.; Anadolu Ö.; Afrashí F.; Yilmaz B.; Gökmen N.OBJECTIVE: The aim of this prospective study was to detect risk factors for visual impairment or changes in vision following spinal fusion surgery. METHODS: A total of 68 patients aged 18–65 years, scheduled for posterior spinal fusion surgery, were included. Ophthalmic examinations were performed by an ophthalmologist on the day before surgery and repeated after the second postoperative day, within the first postoperative week. Patient characteristics were compared according to two clinical outcomes following surgery: worsening of vision during the pre- and postoperative interval (group 1) and no change in preand postoperative examinations (group 2). RESULTS: The mean age of patients with postoperative visual changes was significantly higher than that for patients without postoperative visual changes. Total number of female patients and use of intraoperative ephedrine to treat hypotensive episodes were significantly higher in group 1 than in group 2 patients. CONCLUSION: Older age, female gender and intraoperative hypotensive episodes are potential risk factors for postoperative visual impairment in patients who have undergone spinal fusion surgery. © 2012 SAGE Publications Ltd.Öğe Ultrasonic pretreatment of carrot slices: Effects of sonication source on drying kinetics and product quality(NLM (Medline), 2019) Yilmaz B.; Cakmak H.; Tavman S.In this study effects of ultrasonic pretreatment with different sonication sources on drying behavior of carrot slices were evaluated. Fresh carrot slices were pretreated with ultrasonic probe at 65, 75 and 85 W or ultrasonic bath at 10, 20 and 30°C for 3, 5 and 10 min before air drying. Water gain % and solid loss % of pretreated samples were calculated and color values, ß-carotene content and rehydration ratios of dried samples were determined. Drying behavior of the pretreated samples was evaluated and the drying data were fitted to thin layer drying models. Constant drying rate period was not observed for the carrot slices; however two definite falling-rate periods having different slopes were obtained. Drying time was significantly reduced (up to 20%) depending on the type of pretreatment. The redness value, total color difference and Chroma values of pretreated and control samples were in the same group (p>0.05). ß-carotene content of ultrasonic bath pretreated samples were significantly higher than the samples pretreated with ultrasonic probe and the sample dried without any pretreatment as well (p<0.05). Also rehydration ratios of control samples were found lower than the ultrasound pretreated samples.
