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    Effects of resveratrol on ovarian morphology, plasma anti-mullerian hormone, IGF-1 levels, and oxidative stress parameters in a rat model of polycystic ovary syndrome
    (SAGE Publications Inc., 2015) Ergenoglu M.; Yildirim N.; Yildirim A.G.S.; Yeniel O.; Erbas O.; Yavasoglu A.; Taskiran D.; Karadadas N.
    Objective: To evaluate the effects of resveratrol in a rat model of polycystic ovarian syndrome (PCOS). Study Design: After PCOS model was formed by subcutaneous dihydrotestosterone pellets, rats were randomly divided into 2 groups. The first group (n = 7) was treated with 1 mL/kg/d isotonic saline and the second group (n = 7) was treated with 10 mg/kg/d resveratrol. Seven rats were taken as controls without any medication. Results: Our results showed (1) significant reduction in the number of antral follicle counts (P < .01); (2) significantly decreased plasma anti-Mullerian hormone and insulin-like growth factor 1 levels (P < .01 and P < .05, respectively); (3) significantly lower superoxide dismutase activity (P < .05); and (4) significantly increased glutathione peroxidase content (P < .01) following resveratrol treatment. Conclusion: Resveratrol appears to be effective in the treatment of PCOS due to its antioxidant properties. Future clinical studies with different dosages might provide useful implementations to our practice. © The Author(s) 2015.
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    Isolated torsion of the fallopian tube with ectopic pregnancy: Case report
    (Turkiye Klinikleri, 2014) Yildirim N.; Yildirim A.G.S.; Akdemir A.; Ergenoglu A.M.; Yeniel A.O.
    Isolated tubal torsion containing an ectopic pregnancy is a very rare event. Ectopic pregnancy may also cause these symptoms and may impede the diagnosis of tubal torsion when these two coexist. We present a case with isolated fallopian tube torsion containing an ectopic pregnancy. A 25-year-old gravida 2, parity 0 woman presented with left lower abdominal pain and vaginal bleeding. Sonography revealed a 2 cm adnexal mass adjacent to the left ovary. ß-hCG level was 157 mIU/ml. Laparoscopy depicted torsion of the left fallopian tube together with an ectopic pregnancy. Left salpingectomy was performed. The clinician should also think about tubal torsion when the pain is intermittent and if he suspicious about the ectopic pregnancy. Copyright © 2014 by Türkiye Klinikleri.