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Öğe Amicrobial pustulosis of the folds associated with autoimmune disorders: report a new case of Sjogren's syndrome(Medcom Ltd, 2020) Dirican, F.; Acar, A.; Yaman, B.; Keser, G.; Karaarslan, IAmicrobial pustulosis of the folds is a relatively new entity, characterised by recurring aseptic pustular lesions, predominantly involving the cutaneous folds and occurring in patients with autoimmune disorders. Few cases have been reported in the literature. We present a case of amicrobial pustulosis of the folds in a woman with Sjogren's syndrome.Öğe Amniotic Membrane Transplantation for Reconstruction of Ocular Surface Lesion Excisions in Pediatric Population(NLM (Medline), 2023) Bulut, O.; Palamar, M.; Yaman, B.; Egrilmez, S.; Yagci, A.; Barut, Selver, O.PURPOSE: To define the use of human amniotic membrane transplantation (hAMT) for reconstruction of the ocular surface after ocular surface lesion excisions in pediatric population during the last decade in a tertiary eye center. METHODS: A total of 31 patients who underwent hAMT procedure because of the excision of ocular surface lesions between January 2009 and December 2021 were included in this study. The medical data were retrospectively evaluated. RESULTS: The female-to-male ratio was 14/17. The mean age of the patients was 10.1±4.1 (range, 1-18) years. Although a single hAMT was applied to most of the cases (94.4%; 34 eyes), more than one hAMT was applied to 5.6% of cases (2 eyes). The amniotic membrane degradation duration was found to be 21.5±10.8 (range, 13-50) days. CONCLUSIONS: Amniotic membrane is used as a biomaterial in various ocular surface diseases with its anti-inflammatory, antimicrobial, and wound healing properties. Although widely used, there are only a few studies reporting its clinical efficacy in the pediatric age group. It seems to be safe and effective in pediatric age group for ocular surface reconstruction after ocular surface lesion excisions. Copyright © 2023 Contact Lens Association of Ophthalmologists.Öğe Blue-white variant of pigmented basal cell carcinoma(Elsevier Taiwan, 2018) Turkmen, M.; Turk, B. Gerceker; Karaarslan, I. Kilinc; Yaman, B.; Ozdemir, F.Background: Basal cell carcinoma (BCC) is the most frequent of all skin cancers in the white population. The typical dermoscopic features of pigmented BCCs have been well known. In the literature a new dermoscopic pattern of BCC has been reported as "blue-white variant". Objective: In this study, we aimed to evaluate the blue-white variant of BCC's seen in our cases at our Dermato-oncology Unit. Methods: Patient files between the years 2003-2011 were searched for the cases with the histopathologic diagnosis of BCC. Among them, the cases that were compatible with the diagnosis of blue-white variant of BCC were determined. The morphological and clinical features of the lesions, dermoscopic images together with the histopathological slides were all evaluated. Results: Among 350 histopathologically proven BCCs, 3.1% of them showed diffuse blue-white areas, namely "the blue-white variant". On histopathological examination, typical aggregates of basaloid cells with nuclear atypia connected focally to the epidermis were observed. To our knowledge, this is the first research about the blue-white variant of pigmented BCC. Conclusion: The blue-white variant of pigmented BCC seems to be the most challenging type of BCC in the diagnosis for the clinician. Copyright (C) 2018, Taiwanese Dermatological Association. Published by Elsevier Taiwan LLC.Öğe Can amyloid patterns at salivary gland biopsies give clues for amyloidosis subtyping?(Springer, 2017) Bingul, K. B.; Yaman, B.; Kumbaraci, B. Sarsik; Akalin, T.; Kabasakal, Y.; Sen, S.Öğe Clinical Approach to Ocular Cicatricial Pemphigoid(NLM (Medline), 2023) Çiftçi, M.D.; Korkmaz, İ.; Palamar, M.; Yaman, B.; Eğrilmez, S.; Yağcı, A.; Akalın, T.Objectives: To evaluate the demographic data, ocular and systemic findings, clinical management, and outcomes of patients with ocular cicatricial pemphigoid (OCP). Materials and Methods: The medical records of 11 patients diagnosed as having OCP in the ophthalmology department of Ege University between 2008 and 2021 were evaluated retrospectively. Results: The patients' mean follow-up time was 14±5.76 months. All eyes (100%) had conjunctival involvement and 18 (81.81%) had corneal involvement. According to the Tauber staging system, 7 (31.81%), 8 (36.36%), and 7 (31.81%) of the eyes were stage 2, 3, and 4, respectively. The diagnosis was confirmed in 6 (66.66%) of 9 patients who underwent biopsy. Amniotic membrane transplantation was performed in 7 eyes, entropion surgery in 2 eyes, and electrocauterization for trichiasis in 5 eyes. Systemic involvement was observed in 45.45% (5/11) of patients, most commonly oral mucosal involvement (18.18%). Review of medical records showed that alkylating agents, steroids, and dapsone were used in patients treated before 2020. Mycophenolate mofetil was preferred to be used in combination with corticosteroids. Although treatment responses before mycophenolate mofetil usage could not be evaluated well because of loss to follow-up, 4 (66.66%) of 6 patients who received steroid treatment combined with mycophenolate mofetil showed partial or complete clinical remission. No serious side effects and drug withdrawal were observed. Conclusion: OCP is a sight-threatening autoimmune disease that affects older adults. Although positive biopsy results are valuable for diagnosis, negative results do not exclude the diagnosis. The main treatment is systemic immunosuppressives. Disease activity can be suppressed, especially with early initiation of drug therapy. These patients require a multidisciplinary approach. Especially in the presence of isolated ocular findings, ophthalmologists should be able to make the decision to start immunosuppressive treatment, and systemic treatment should not be delayed. ©Copyright 2023 by Turkish Ophthalmological Association | Turkish Journal of Ophthalmology, published by Galenos Publishing House.Öğe Cutaneous histopathological findings in systemic amyloidosis(Springer, 2022) Yaman, B.; Gomez Gonzalez, C. A.; Acar, A.; Akalin, T.; Kumbaraci, B. Sarsik; Celtik, A.; Sen, S.[No Abstract Available]Öğe Cutanosis amyloidosis: A study with Tioflavin-t and Congo-red staining(Springer, 2016) Igde, B.; Yaman, B.; Turk, B. Gerceker; Akalin, T.; Sen, S.Öğe Desmoid type fibromatosis: Clinicopathologic analysis of 113 cases(Springer, 2017) Buyuktalanci, E.; Yaman, B.; Akalin, T.Öğe The diagnostic value of cell blocks in Liquid-Based Cytology of bronchial aspiration and bronchial brushing materials(Wiley, 2018) Sadullahoglu, C.; Yaman, B.; Veral, A.; Nart, D.IntroductionFibreoptic bronchoscopy is used for the diagnosis and treatment of several pulmonary diseases. Conventional smear and Liquid-based cytology (LBC) methods are applied to cytology samples of various bronchoscopic techniques. If the cytology sample is sufficient for evaluation, a cell block (CB) can be prepared from the remaining material. The aim of this study is to identify the diagnostic value of conventional smear, LBC and CB methods in bronchial cytological specimens. MethodsA retrospective review of 329 samples from 240 patients was made and, of these, 144 patients were found to have neoplasia. A blind review of the specimens was performed and all were reclassified individually. The endoscopic findings of the 144 patients with neoplasia were analysed retrospectively. The cytological diagnoses were then compared with the final diagnosis or the endoscopic findings of patients with neoplasia. The sensitivity was calculated for each method, both separately and together. ResultsIt was determined that CB led to a 10.1% increase in the diagnostic sensitivity for bronchial aspiration (BA) specimens, while no significant increase was seen in bronchial brush specimens. In BA specimens of neoplasia patients with normal bronchoscopic findings, while three methods were applied together with an increase in the number of cases diagnosed as malignant cytology, there was no significant increase in bronchial brush specimens. ConclusionThis study demonstrated that adding cell block to CB and LBC seemed to contribute the cytological diagnosis in BA materials significantly. Another advantage of CB is the opportunity of applying advanced methods such as immunocytochemical and molecular techniques. Additional methods applied to bronchoscopic cytology and histology samples enable performing further studies in the diagnosis of lung cancer, as well as molecular analysis. This study aimed to investigate the diagnostic value of conventional smears, liquid-based cytology and cell blocks prepared from bronchial aspiration and brush materials by comparison with the final diagnosis based on histologic, radiologic and clinical data.Öğe Diffuse Idiopathic Pulmonary NeuroEndocrine Cell Hyperplasia (DIPNECH) in association with a sclerosing hemangioma: A case report(Springer, 2013) Yaman, B.; Nart, D.; Cagirici, U.; Veral, A.Öğe Doxepin-induced bullous pemphigoid-like drug eruption(Wiley-Blackwell, 2016) Iskandarli, M.; Yaman, B.; Turk, B. Gerceker; Ozturk, G.Öğe Expression of c-KIT in malignant melanoma subtypes: An immunohistochemical study(Springer, 2017) Yaman, B.; Soyluer, U.; Akalin, T.Öğe Keratosis Lichenoides Chronica (Nekam’s Disease): Dermoscopic and in Vivo Reflectance Confocal Microscopy Findings(Mattioli 1885, 2023) Ozturk, A.; Acar, A.; Yaman, B.; Karaarslan, I.[No abstract available]Öğe Large-cell transformation of mycosis fungoides: Report of 11 cases(Springer, 2017) Soyluer, U.; Yaman, B.; Ozsan, N.; Akalin, T.; Turk, B. Gerceker; Ertam, I.; Ozturk, G.; Hekimgil, M.Öğe Malignant melanoma in a patient with leptomeningeal melanocytosis: A case report(Springer, 2013) Pehlivanoglu, B.; Ertan, Y.; Yaman, B.; Turhan, T.; Akalin, T.Öğe Melanoma arising in chronic ulceration associated with lymphoedema(Ma Healthcare Ltd, 2013) Turk, B. G.; Bozkurt, A.; Yaman, B.; Ozdemir, F.; Unal, I.Chronic ulceration can be complicated by development of a malignancy. The most frequent associated malignances are squamous cell carcinoma and basal cell carcinoma, although melanoma, leiomyosarcoma and adenocarcinoma are less commonly seen. Chronic lymphoedema may also predispose to development of some malignancies, including lymphangiosarcoma, squamous cell carcinoma and Kaposi's sarcoma. Here, we report the case of a 77-year-old man with primary lymphoedema, who developed melanoma in a chronic foot ulcer of 60 years' duration. The patient underwent wide excision for the melanoma, and remains free from metastases at 1-year follow up.Öğe Melanoma arising in chronic ulceration associated with lymphoedema(Ma Healthcare Ltd, 2013) Turk, B. G.; Bozkurt, A.; Yaman, B.; Ozdemir, F.; Unal, I.Chronic ulceration can be complicated by development of a malignancy. The most frequent associated malignances are squamous cell carcinoma and basal cell carcinoma, although melanoma, leiomyosarcoma and adenocarcinoma are less commonly seen. Chronic lymphoedema may also predispose to development of some malignancies, including lymphangiosarcoma, squamous cell carcinoma and Kaposi's sarcoma. Here, we report the case of a 77-year-old man with primary lymphoedema, who developed melanoma in a chronic foot ulcer of 60 years' duration. The patient underwent wide excision for the melanoma, and remains free from metastases at 1-year follow up.Öğe Prognostic significance of bcl-2, c-myc and survivin in synovial sarcoma(Springer, 2012) Demir, D.; Yaman, B.; Anacak, Y.; Kececi, B.; Kandiloglu, G.; Akalin, T.Öğe Prognostic significance of nuclear grade in malignant pleural mesothelioma: A single institution experience(Springer, 2016) Erbil, S.; Yaman, B.; Cevik, A.; Ertan, Y.; Ozdil, A.; Veral, A.; Nart, D.Öğe Prognostic significance of p63, TTF-1 and maspin in non-small cell lung carcinomas(Springer, 2013) Yaman, B.; Nart, D.; Cok, G.; Veral, A.
