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Öğe The comparison of the effects of hormone replacement therapy with the combination of pulsed estrogen-medroxyprogesterone acetate and the conjugated estrogen-medroxyprogesterone acetate on vosomotor complaints and uterine bleeding patterns in physiologic postmenopausal patients [Dogal menopozda olan olgularda pulse östrojen- medroksiprogesteron asetat kombinasyonu ve konjuge östrojen- medroksiprogesteron asetat i·le yapilan hormon replasman tedavilerinin vazomotor yakinmalara ve uterin kanamalara olan etkilerinin karş ilaştirilmasi](2005) Özşener S.; Akercan F.; Çirpan T.; Coşan Terek M.; Itil I.M.; Yücebilgin S.OBJECTIVE: The comparison of the effects of hormone replacement therapy with pulse estrogen-medroxyprogesterone acetate and conjugated estrogene-medroxyprogesterone acetate on vasomotor complaints and uterine bleeding patterns in physiologic postmenopausal patients. STUDY DESIGN: Total 80 cases who were admitted to Ege University Medical Faculty Gynecology Department's Menopause Clinic between January 2002-January 2004 and using these regimens were included for this retrospective study. The hormone replacement therapy preperations which were the subject of this study were: the combination of estradiol hemihydrate (aerodiol, 150 meg, Servier) and medroxyprogesterone acetate (Farlutal, 5 mg, Deva) as pulsed estrogen-MPA and estrogen 0,625 mg and medroxyprogesterone acetate 5 mg (Premelle Cycle, Wyeth) as conjugated estrogen-MPA combination. There were 30 cases in pulsed estrogen-MPA group and 50 patients in conjugated estrogen-MPA group. RESULTS: The average age of the patients was 50.912.5 years. There were no significant difference between the age, menopausal age, body-mass index (BMI) and postmenopausal period of the groups (p>0.05). There were no significant difference in hot flush frequencies (average 8.60±3.23) (p>0.05). Kupperman index values on initial, third and sixth months were 27.3±4.8; 10.2±2.9; 9.5±2.7 in pulsed estrogene-MPA group and 7.9±5.9; 10.5±2.3 ve 10.2±2.1 in conjugated estrogen-MPA group and no significant difference were found between the groups (p>0.05). The withdrawal bleeding was seen more frequently in oral conjugated estrogen-MPA group. But the difference was not significant (p=0.061). In the same way, the irregular bleeding (every bleeding pattern except withdrawal bleeding) episodes were seen in conjugated estrogen-MPA group more than the other group but, the difference was not significant (p=0.426). CONCLUSION: The efficacy and tolerability of pulse estrogene-MPA therapy in physiological postmenopausal patients was similar to oral conjugated estrogene-MPA therapy and could be used as an effective therapeutic choice.Öğe Conservative management of placenta previa percreta by leaving placental tissue in situ with arterial ligation and adjuvant methotrexate therapy [Plasenta previa perkreata'li{dotless} olgunun plasental dokunun çi{dotless}kari{dotless}lmadan, arter ligasyonu ve adjuvan metotreksat terapisi ile konservatif yönetimi](2011) Çirpan T.; Sanhal C.Y.; Yücebilgin S.; Özşener S.Placenta percreta is one of the life-threatening conditions in modern obstetrics. The rising caesarean section rate means rising placenta percreta rate. Treatment strategies range from a caesarean hysterectomy to leaving the placenta in situ with or without internal iliac artery ligation/uterine artery embolisation and/or methotrexate therapy. We describe a case of placenta previa percreta which we managed successfully with conservative modalities.Öğe Laparoscopic approach of uterin fibroids [Uterin miyomlara laparoskopik yaklaşim](2013) Şendag F.; Akdemir A.; Yildirim A.S.; Yücebilgin S.; Akman L.; Karadadaş N.; Öztekin K.Objective: Assessment of demographic and clinical outcomes of patients that were un derwent laparoscopic myomectomy. Material and Methods: We reviewed 99 patients that under went laparoscopic myomectomy in the years 2005 2009 at the Ege Lniversity Gynecology and Obstetrics Department with respect operation duration, blood loss, indication, perioperative and postoperative complication. Results: The main indications for surgery were menorrhagia (n:24), pelvic pain (n:8), infertility (n:47), adnexal mass with myoma (n:18), and ectopic pregnancy with myoma (n:2). The avarege number of myomas were 1 4. Eighty three (84%) patients has only one myoma. The location of myomas were fundal (34%), posterior (33%), anterior (22%), lateral and in traligamentous (1 1%). 122 myomas were extirpation of the uterus. Of the fifty four patients, uter me defect was sutured after extirpation of the myomas. The avarage operation time was 100(80 165, range) minutes and hospital stay was 1.5 (1 3 days, range) days. Conclusion: In this study, laparos copic myomectomy was preferable methods in selected cases because of successful results, accep table complication rates, and shorter length of hospital stay. Copyright © 2013 by Türkiye Klinikleri.Öğe Post-mortem Caesarean section performed 30 minutes after maternal cardiopulmonary arrest(2004) Kazandi M.; Mgoyi L.; Gundem G.; Hacivelioglu S.; Yücebilgin S.; Özkınay E.[No abstract available]
