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  • Küçük Resim Yok
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    An analysis of nursing and medical students' attitudes towards and knowledge of complementary and alternative medicine (CAM)
    (Wiley-Blackwell Publishing, Inc, 2010) Yildirim, Yasemin; Parlar, Serap; Eyigor, Sibel; Sertoz, Ozen O.; Eyigor, Can; Fadiloglu, Cicek; Uyar, Meltem
    Aims and objectives. This study aims to evaluate and compare nursing and medical students' attitudes and knowledge about complementary and alternative medicine (CAM). Background. Despite increased popularity of the use of complementary and alternative medicine, it is not included in nursing and medicine schools' curricula in many countries. Design. A cross-sectional design was used. Method. This study's research population included 972 students who were educated at a school of nursing and a faculty of medicine during the academic year 2006-2007. The study used a questionnaire the researchers prepared as data collection form. Pearson chi-square test was used to observe the differences between nursing and medical students. A p-value < 0 center dot 05 was accepted statistically significant. Results. The population was 49 center dot 1% nursing students and 50 center dot 9% medical students. Of the nursing students, 57 center dot 8% agreed with the statements that complementary and alternative medicine modalities should be integrated into clinical practice, 61 center dot 3% agreed for curriculum. Of the medical school students, 32 center dot 6% agreed for clinical practice and 37 center dot 9% for curriculum. The nursing students had sufficient knowledge of mostly massage and imagery; and medical students had sufficient knowledge of mostly diet therapy, vitamins and prayer. Conclusions. The results of current study reveal that nursing students adopt more positive attitudes than medical students towards complementary and alternative medicine therapies and that both student groups have limited knowledge of complementary and alternative medicine modalities. Relevance to clinical practice. Physicians and nurses play important roles in helping patients use complementary and alternative medicine safely and accurately. Therefore, as future nurses and physicians, nursing and medical students should have sufficient knowledge of and education on complementary and alternative medicine modalities. In this context, handling complementary and alternative medicine on a scientific scale and including it in nursing and medical students' educational programmes should be among the goals and plans in Turkey.
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    Analysis of the antinociceptive effect of systemic administration of tramadol and dexmedetomidine combination on rat models of acute and neuropathic pain
    (Pergamon-Elsevier Science Ltd, 2007) Guneli, Ensari; Yavasoglu, N. Ulkue Karabay; Apaydin, Sebnem; Uyar, Meltem; Uyar, Mehmet
    The aim of the present study was to investigate the possible antinociceptive effect of systemic administration of tramadol and dexmedetomidine either alone or in combination on acute and neuropathic pain models in rats. The antinociceptive effects of intraperitoneal (i.p.) tramadol (520 mg/kg) and dexmedetomidine (5-20 mu g/kg) and three different combinations of tramadol+dexmedetomidine (5 + 5, 5 + 10 and 10+ 5, mg/kg+ mu g/kg, respectively) were measured by tail-flick and hot-plate methods in acute pain. The effects on the sciatic nerve ligation-induced neuropathic pain was tested by i.p. administration of tramadol (5 mu g/kg), dexmedetomidine (5 mu g/kg) and tramadol + dexmedetomidine combination (5 + 5) using a thermal plantar test. Sedation/motor-incoordination was assessed on rotarod. Tramadol and dexmedetomidine produced dose-related antinociception in tail-flick and hot-plate tests. In both tests, combination of these drugs produced an antinociceptive effect that is greater than that produced by tramadol. or dexmedetomidine alone at several time points. In hot-plate test, tramadol + dexmedetomidine combination (5 + 10) exerted the strongest antinociceptive effect, while tramadol + dexmedetomidine combination (10 + 5) was significantly most effective in tail-flick test. In the neuropathic pain, the antinociceptive effect exerted by tramadol + dexmedetomidine combination (5 + 5) was also significantly greater than their applications alone. In rotarod test, tramadol (30 and 40 mg/kg), dexmedetomidine (30 and 40 mu g/kg), tramadol+dexmedetomidine combination (10+10, 20+20) produced sedation/motor-incoordination, whereas tramadol (5-20 mg/kg), dexmedetomidine (5-20 mu g/kg) and tramadol + dexmedetomidine combination (5 + 5, 5 + 10 and 10 + 5) did not produce any effect on sedation/motor-incoordination. The combination of tramadol and dexmedetomidine was more effective in increasing the pain threshold in acute and neuropathic pain when compared with the administration of either of these drugs alone. (C) 2007 Elsevier Inc. All rights reserved.
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    Attribution of changes in the water balance of a basin to land-use changes through combined modelling of basin hydrology and land-use dynamics
    (Iwa Publishing, 2022) Gunacti, Mert Can; Kandemir, Fulya Aydin; Najar, Mohamed; Kuzucu, Aysegul; Uyar, Meltem; Barbaros, Filiz; Boyacioglu, Hulya
    Land use and land cover change (LULCC) is considered one of the major drivers of climate change, although climate change can also foster direct or indirect influences leading to LULCC. The objective of the presented study is to offer a strategic observation frame as the land use and land cover (LULC) transitions are grouped to define the cover flows (CFs). The Kucuk Menderes River Basin (KMRB), which is located in the west of Turkey was examined as the case study. Through LULCC modelling via the employment of multi-layer perceptron (MLP), cellular auto -mata (CA), and Markov Chain methods, future LULC maps were projected up to the horizon of 2050. Hydrologic responses of the basin to LULCC were determined by the developed hydrologic model, which is generated by the Soil and Water Assessment Tool (SWAT). The super-imposed impacts of the examined effects of LULCC have been investigated by the CF types. This way, the individual impacts of the CFs have been assessed. In the case of the KMRB, projected annual runoffs for the year 2050 cover map represent a 9.06% reduction and the major responsible CF type for this reduction is the conversion from forest to non-irrigated agricultural land cover by 22.90%.
  • Küçük Resim Yok
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    Combination therapy in treatment of peripheral diabetic neuropathy with severe pain in an adolescent patient
    (Wiley-Blackwell Publishing, Inc, 2009) Eyigor, Can; Uyar, Meltem; Pirildar, Sebnem; Coker, Mahmut
  • Küçük Resim Yok
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    Comparison of propofol and ketamine anaesthesia ( With special reference to hemodynamic properties )
    (1998) Özçağ, Özant; Uyar, Meltem; Eronat, Ahmet Cemal
    Bu çalışmanın amacı, genel anestezi indüksiyonunda uygulanan ketamin (Ketalar®) ve propofol (Diprivan®))'un hemodinamik etkilerinin karşılaştı-rılmağıdır. Bu çalışma handikaplı çocukların dental tedavilerini gerçekleştirme esnasında kullanılacak güvenilir ve konforlu bir anestezik ajanı araştırmak nıaksatıvia planlandı. Çalışmada ASA I ve ASA II sınıfına dahil toplam 27 adet handikaplı çocuk yer aldı.Tüm uygulamalarda propofol ve ketamin indüksiyon ajanı olarak kullanıldı. Anestezilerin idamesi ise halotan ve nitröz-oksit oksijen inhalasyon anestezisiyle sağlandı. Kan basıncı, kalp atım hızı ve kan oksijen doygunluğuna ait veriler istatistiksel olarak Mann Whitney Confidence Interval and Test Metodu ile hesaplandı. Her ne kadar başlangıca ait hemodinamik parametrelerde, anestezi öncesi değerlere göre, her iki ilaç grubunda da istatistiksel olarak anlamlı değişikliklere rastlamamıza rağmen, bu farklılıklar tolere edilebilir düzeydeydi. Sonuçta, ne propofol ne de ketamin hemodinamik özellikleri bakımından birbirlerine belirgin bir üstünlük göstermediler.
  • Küçük Resim Yok
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    Comparison of the effects of remifentanil and remifentanil plus lidocaine on intubation conditions in intellectually disabled patients
    (Elsevier Science Inc, 2014) Eyigor, Can; Cagiran, Esra; Balcioglu, Taner; Uyar, Meltem
    Background and objectives: This is a prospective, randomized, single-blind study. We aimed to compare the tracheal intubation conditions and hemodynamic responses either remifentanil or a combination of remifentanil and lidocaine with sevoflurane induction in the absence of neuromuscular blocking agents. Methods: Fifty intellectually disabled, American Society of Anesthesiologists I-II patients who underwent tooth extraction under outpatient general anesthesia were included in this study. Patients were randomized to receive either 2 mu g kg(-1) remifentanil (Group 1, n = 25) or a combination of 2 pg kg(-1) remifentanil and 1 mg kg(-1) lidocaine (Group 2, n = 25). To evaluate intubation conditions, Helbo-Hansen scoring system was used. In patients who scored 2 points or less in all scorings, intubation conditions were considered acceptable, however if any of the scores was greater than 2, intubation conditions were regarded unacceptable. Mean arterial pressure, heart rate and peripheral oxygen saturation (SpO(2)) were recorded at baseline, after opioid administration, before intubation, and at 1, 3, and 5 min after intubation. Results: Acceptable intubation parameters were achieved in 24 patients in Group 1 (96%) and in 23 patients in Group 2 (92%). In intra-group comparisons, the heart rate and mean arterial pressure values at all-time points in both groups showed a significant decrease compared to baseline values (p = 0.000) Conclusion: By the addition of 2 mu g/kg remifentanil during sevoflurane induction, successful tracheal intubation can be accomplished without using muscle relaxants in intellectually disabled patients who undergo outpatient dental extraction. Also worth noting, the addition of 1 mg/kg lidocaine to 2 mu g/kg remifentanil does not provide any additional improvement in the intubation parameters. (C) 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.
  • Küçük Resim Yok
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    Comparison of the efficacy of continuous radiofrequency thermocoagulation, pulsed radiofrequency denervation applications, and TENS therapies for lumbar facet syndrome: A single-blind randomized controlled trial
    (Kare Publ, 2024) Secgin, Atilla; Eyigor, Sibel; Eyigor, Can; Uzuner, Bora; Koken, Idris Sevki; Uyar, Meltem
    Objectives: We aimed to compare the effectiveness of TENS, used in physical therapy departments, and continuous radiofrequency thermocoagulation (CRF) and pulsed radiofrequency denervation (PRF), used in algology departments, in patients with lumbar facet syndrome (LFS). Methods: Subjects were selected from patients with LFS visiting outpatient clinics of physical therapy and algology departments at Ege University School of Medicine, whose pain was refractory to medical treatment for at least 3 months. Subjects were randomized into 3 groups. A total of 60 patients, with 20 in each group, were enrolled. The first group received CRF, the second group received TENS for 30 minutes a day for 15 days, and the third group received PRF. Patients were assessed at baseline, at the end of the first and sixth months, for a total of three times. Results: Improvements at month 1 and month 6 were found to be statistically significant in all three treatment groups with respect to their pain scores, Oswestry Disability Indexes, hand-floor distance measurements, 20-meter walking times, 6-min walking distances, Beck Depression Inventory, and most of the SF-36 domain scores (p0.05). Conclusion: We suggest that it might be more appropriate to use TENS, a non-invasive treatment, before trying more invasive procedures like CRF and PRF in these patients. However, it has been stated that further studies involving a larger patient sample are needed.
  • Küçük Resim Yok
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    Developing an ethical attitude scale for pain management in nursing
    (Kare Publ, 2024) Namik, Emre; Akin, Esra; Uyar, Meltem
    Objectives: The aim of this study is to develop the Developing an Ethical Attitude Scale for Pain Management in Nursing to assign the ethical attitudes of nurses in pain management. Methods: The population of the study comprised nurses (n=411) working in a university hospital in & Idot;zmir. The Ethical Attitude Scale in Nursing Pain Management was developed in five sub-dimensions: Care and Dignity, Ethical Values, Attitude, Rights, and Pain Management. This scale was created by examining many research studies related to pain management in nursing in the literature and taking expert opinions. The Ethical Attitude Scale in Nursing Pain Management initially consisted of 36 items. After expert opinions and validity analyses, the draft scale was reduced to 34 items, and then reliability analysis further reduced the scale to 23 items. Results: In the validity and reliability study of The Ethical Attitude Scale in Nursing Pain Management, the total Cronbach's alpha value of the scale was 0.86. The Cronbach's alpha value for the Care and Dignity sub-dimension was 0.88; for the Ethical Values sub-dimension, it was 0.83; for the Attitude sub-dimension, it was 0.86; for the Rights sub-dimension, it was 0.79; and for the Pain Management sub-dimension, it was 0.72. Conclusion: According to these data, it was determined that The Ethical Attitude Scale in Nursing Pain Management is a valid and reliable scale.
  • Küçük Resim Yok
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    Effect of Inhalation Aromatherapy on Pain, Anxiety, Comfort, and Cortisol Levels During Trigger Point Injection
    (Lippincott Williams & Wilkins, 2020) Kasar, Kadriye Sayin; Yildirim, Yasemin; Senuzun Aykar, Fisun; Uyar, Meltem; Sagin, Ferhan Girgin; Atay, Sevcan
    The objective of this study was to examine the effects of inhaler aromatherapy on the level of pain, comfort, anxiety, and cortisol during trigger point injection in individuals with myofascial pain syndrome. Lavender oil inhalation was found to reduce pain and anxiety during trigger point injection and to improve patient comfort, but it did not affect the saliva cortisol level.
  • Küçük Resim Yok
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    Effects of Covid-19 pandemic on algology practice: single-center clinical study results
    (2023) Özalp Horsanalı, Burcu; Yilmaz, Husnu; Özgül, Kazım Koray; Uyar, Meltem; Eyigör, Can
    Aim: During the Covid-19 pandemic, the number of patients examined in the outpatient clinic of many health institutions was limited and some changes were made in the treatment protocols. Regional Anesthesia and Pain Associations also recommended steroid administration and opioid use restriction, especially in chronic pain. In our study, we aimed to evaluate the clinical diagnosis of the patients who applied to our clinic with complaints of pain, the treatments they received, and whether our approach to chronic pain was by the guidelines during the Covid-19 pandemic period. Material and Methods: Demographic data, clinical diagnoses, interventional procedures, and medical treatments given to the patients who applied to the Ege University Faculty of Medicine, Algology Department outpatient clinic between March 2020 and May 2021 were evaluated statistically by retrospective analysis. Results: The mean age of 444 patients included in the study was 56.8±15.9 years. It was found that 29 (6.5%) of the patients applied for acute pain and 415 patients (93.5%) for chronic pain. While the number of patients who received only pharmacological treatment was 230 (51.8%), it was determined that 199 (44.8%) patients received both pharmacological treatment and interventional procedure, and 15 (3.3%) patients received only interventional procedure. When the patients were investigated in terms of pharmacological treatment, we observed that 229 (57.1%) patients received only paracetamol treatment, 99 (24.6%) patients received only non-steroidal anti-inflammatory (NSAI) drug therapy, and 73 (18.2%) patients received both paracetamol and NSAI therapy. It was determined that 243 (96.8%) of the patients who received medical treatment received weak opioids, 3 (1.3%) patients received strong opioids, and 5 (1.9%) patients received both weak and strong combined opioid treatment. Steroid injection was observed in only 16.3% of 214 patients who underwent interventional procedures. Conclusion: It was observed that chronic pain patients were in the majority during the pandemic period and the use of strong opioids and steroid injections were minimized in these patients. Since it may cause changes in immune responses, applications that will pose the least risk in pain patients should be chosen during the pandemic period.
  • Küçük Resim Yok
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    The effects of covid-19 pandemic on the educational status of medical residents of anesthesiology in Türkiye – a survey analysis
    (2023) Zı?ncı?rcı?og?lu, C?iler; Uyar, Meltem; Yu?ksel, Aslıhan Esra; S?ahutoglu, Cengiz; O?zbı?lgı?n, S?ule
    Aim: COVID-19 has been one of the biggest challenges that education systems have ever faced. The aim of this study is to determine the educational deficiencies of Medical Residents of Anesthesiology and Reanimation during the COVID-19 pandemic in Turkey. Materials and Methods: Our study was carried out after the approval of the Ministry of Health and Ege University Medical Faculty Hospital Ethics Committee. This study is a cross-sectional survey study. A web-based questionnaire containing 32 questions was sent to the Anesthesiology and Reanimation Specialization Students in Education and Research Hospitals and University Hospitals in Turkey, in a computer environment, by sending it via e-mail with the approval of the Turkish Society of Anesthesiology and Reanimation. Results: The training hours decreased significantly in both University Hospitals and Ministry of Health Training and Research Hospitals (p<0.001). This decrease was significantly higher in Ministry of Health Training and Research Hospitals than in University Hospitals (p=0.032). The resident training process during the pandemic has been interpreted as tiring by 89%, stressful by 85%, and humiliating by 35% of the participants. Conclusion: During the COVID-19 pandemic period, anesthesia assistants both actively participated in COVID-19 patient treatment and continued their operating room missions. During this period assistant training was delayed or canceled. Considering the continuity of the pandemic, we think that we need to develop online training programs and determine the service-training balance well to protect the future of our expertise. These results reveal that residency training should be reorganized during the pandemic period.
  • Küçük Resim Yok
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    Effects of intra-articular application of pulsed radiofrequency on pain, functioning and quality of life in patients with advanced knee osteoarthritis
    (Ios Press, 2015) Eyigor, Can; Eyigor, Sibel; Akdeniz, Sedef; Uyar, Meltem
    BACKGROUND AND OBJECTIVE: The number of studies and evidences is inadequate especially with regard to the efficacy of pulsed radiofrequency (PRF) application in non-spinal indications. The purpose of this study was to investigate the effect of PRF on pain, functioning and quality of life in patients with advanced knee OA. METHODS: The study included 21 patients with complaints of knee pain. Intra-articular PRF was applied for 10 minutes at 42 degrees C. Pain severity was assessed using the 10 cm standard visual analogue scale (VAS). Outcome measures also included a 20-meter walk test, a 6-minute walk test, WOMAC, Lequesne index, and the Short Form-36 (SF-36). All measurements were assessed before treatment and 4 and 12 weeks after the treatment. RESULTS: A statistically significant improvement was found in VAS scores at rest and after walking, subscores of SF36-pain and SF36-social functioning, and Lequesne score at week four (p < 0.05). This improvement was maintained for the scores of VAS-walking at week 12 (p < 0.05). CONCLUSION: It is possible to state that intra-articular PRF application is effective and safe for the pain treatment of patients with advanced knee OA. Therefore, we think that PRF application will be included in chronic pain treatment guidelines in the future with the increase in the number of future studies.
  • Küçük Resim Yok
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    The Effects of Music Therapy on Pain in Patients with Neuropathic Pain
    (Elsevier Science Inc, 2014) Korhan, Esra Akin; Uyar, Meltem; Eyigor, Can; Yont, Gulendam Hakverdioglu; Celik, Serkan; Khorshid, Leyla
    The aim of this study was to investigate the effect of relaxing music on pain intensity in patients with neuropathic pain. A quasi-experimental study, repeated measures design was used. Thirty patients, aged 18-70 years, with neuropathic pain and hospitalized in an Algology clinic were identified as a convenience sample. Participants received 60 minutes of music therapy. Classical Turkish music was played to patients using a media player (MP3) and headphones. Participants had pain scores taken immediately before the intervention and at the 30th and 60th minutes of the intervention. Data were collected over a 6-month period in 2012. The patients' mean pain intensity scores were reduced by music, and that decrease was progressive over the 30th and 60th minutes of the intervention, indicating a cumulative dose effect. The results of this study implied that the inclusion of music therapy in the routine care of patients with neuropathic pain could provide nurses with an effective practice for reducing patients' pain intensity. (C) 2014 by the American Society for Pain Management Nursing
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    Effects of Pain Education Program on Pain Intensity, Pain Treatment Satisfaction, and Barriers in Turkish Cancer Patients
    (Elsevier Science Inc, 2009) Yildirim, Yasemin Kuzeyli; Cicek, Fadiloglu; Uyar, Meltem
    The purpose of this randomized controlled study was to investigate the effect of a pain education program (PEP) on pain intensity, patients' satisfaction with pain treatment, and patient-related barriers to pain management among Turkish patients with cancer. The study was conducted in a sample of 40 patients who were hospitalized for cancer and experiencing pain. The patients were equally randomized to either a PEP or a control group. The data were collected by means of the McGill Pain Questionnaire, the Numeric Rating Scale, and the Barrier Questionnaire Revised. After the completion of the questionnaires at the first interview, patients in the PEP group received pain education using a pain educational booklet and an explanatory slide program that discussed the booklet's content with the patients. Patients in the control group received routine clinical care. The questionnaires were reapplied to the patients in both groups after 2, 4, and 8 weeks. Participation in a PEP was associated with decreased pain intensity scores for "present" and "least pain" during weeks 2, 4, and 8 (p < .05). Similarly, there were significant differences between the groups with respect to weeks 2, 4, and 8 satisfaction with pain treatment (p < .05). At the end of second week, the total BQ-r score decreased significantly in the PEP group from 2.12 to 1.29 compared with 2.30 to 2.28 in the control group (p < .001). The findings suggest that the PEP decreases pain intensity, improves satisfaction with treatment, and decreases barriers about cancer pain management in cancer patients. Incorparation of PEP into the standard of care for cancer patients with pain may improve the quality of pain management. (C) 2009 by the American Society for Pain Management Nursing
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    Effects of Pain Education Program on Pain Intensity, Pain Treatment Satisfaction, and Barriers in Turkish Cancer Patients
    (Elsevier Science Inc, 2009) Yildirim, Yasemin Kuzeyli; Cicek, Fadiloglu; Uyar, Meltem
    The purpose of this randomized controlled study was to investigate the effect of a pain education program (PEP) on pain intensity, patients' satisfaction with pain treatment, and patient-related barriers to pain management among Turkish patients with cancer. The study was conducted in a sample of 40 patients who were hospitalized for cancer and experiencing pain. The patients were equally randomized to either a PEP or a control group. The data were collected by means of the McGill Pain Questionnaire, the Numeric Rating Scale, and the Barrier Questionnaire Revised. After the completion of the questionnaires at the first interview, patients in the PEP group received pain education using a pain educational booklet and an explanatory slide program that discussed the booklet's content with the patients. Patients in the control group received routine clinical care. The questionnaires were reapplied to the patients in both groups after 2, 4, and 8 weeks. Participation in a PEP was associated with decreased pain intensity scores for "present" and "least pain" during weeks 2, 4, and 8 (p < .05). Similarly, there were significant differences between the groups with respect to weeks 2, 4, and 8 satisfaction with pain treatment (p < .05). At the end of second week, the total BQ-r score decreased significantly in the PEP group from 2.12 to 1.29 compared with 2.30 to 2.28 in the control group (p < .001). The findings suggest that the PEP decreases pain intensity, improves satisfaction with treatment, and decreases barriers about cancer pain management in cancer patients. Incorparation of PEP into the standard of care for cancer patients with pain may improve the quality of pain management. (C) 2009 by the American Society for Pain Management Nursing
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    The effects of preadministration of local anesthetic on pulsed radiofrequency
    (2018) Arıcı, Tülin; Kurçaloğlu, Mustafa; Köken, İdris Şevki; Uzuner, Bora; Eyigör, Can; Uyar, Meltem
    Background/aim: Pulsed radiofrequency (PRF) has been reported to be a safe and reliable method for the management of a variety of chronic pain syndromes. It is not known whether the preadministration of local anesthetic increases the size of the electrical field. We revealed the effects of administering local anesthetic on PRF and investigated whether they were related to local anesthetic or fluid effects. Materials and methods: Group 1 (n = 18) received PRF to the suprascapular nerve with 1 mL of bupivacaine, group 2 (n = 20) received PRF with 1 mL of physiological saline solution, and group 3 (n = 18) received PRF only. Results: There were significant improvements in visual analog scale (VAS) scores at 30 min, 1 month, and 3 months after treatment in group 1 (P < 0.05) and at 1 month and 3 months in groups 2 and 3 (P < 0.05). There was a significant improvement in VAS scores in group 1 compared with groups 2 and 3 at 30 min after treatment. Conclusion: PRF applied to the nerve along with local anesthetic may increase pain relief, especially in the early posttreatment period. the favorable effects may depend on the pharmacodynamic features of the local anesthetic.
  • Küçük Resim Yok
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    The effects of preadministration of local anesthetic on pulsed radiofrequency
    (Tubitak Scientific & Technical Research Council Turkey, 2018) Arici, Tulin; Kurcaloglu, Mustafa; Koken, Idris Sevki; Uzuner, Bora; Eyigor, Can; Uyar, Meltem
    Background/aim: Pulsed radiofrequency (PRF) has been reported to be a safe and reliable method for the management of a variety of chronic pain syndromes. It is not known whether the preadministration of local anesthetic increases the size of the electrical field. We revealed the effects of administering local anesthetic on PRF and investigated whether they were related to local anesthetic or fluid effects. Materials and methods: Group 1 (n = 18) received PRF to the suprascapular nerve with 1 mL of bupivacaine, group 2 (n = 20) received PRF with 1 mL of physiological saline solution, and group 3 (n = 18) received PRF only. Results: There were significant improvements in visual analog scale (VAS) scores at 30 min, 1 month, and 3 months after treatment in group 1 (P < 0.05) and at 1 month and 3 months in groups 2 and 3 (P < 0.05). There was a significant improvement in VAS scores in group 1 compared with groups 2 and 3 at 30 min after treatment. Conclusion: PRF applied to the nerve along with local anesthetic may increase pain relief, especially in the early posttreatment period. The favorable effects may depend on the pharmacodynamic features of the local anesthetic.
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    Effects of Reflexology on Pain in Patients With Fibromyalgia
    (Lippincott Williams & Wilkins, 2016) Korhan, Esra Akin; Uyar, Meltem; Eyigor, Can; Yont, Gulendam Hakverdioglu; Khorshid, Leyla
    The aim of this study was to investigate the effect of reflexology on pain intensity in patients with fibromyalgia, using an experimental repeated-measures design, and a convenience sample of 30 fibromyalgia inpatients. Thirty patients aged 18 to 70 years with fibromyalgia and hospitalized in the algology clinic were taken as a convenience sample. Patients received a total of 12 60-minute sessions of reflexology over a period of 6 consecutive weeks. Reflexology was carried out bilaterally on the hands and feet of patients at the reflex points relating to their pain at a suitable intensity and angle. Subjects had pain scores taken immediately before the intervention (0 minute), and at the 60th minute of the intervention. Data were collected over a 10-month period in 2012. The patients' mean pain intensity scores were reduced by reflexology, and this decrease improved progressively in the first and sixth weeks of the intervention, indicating a cumulative dose effect. The results of this study implied that the inclusion of reflexology in the routine care of patients with fibromyalgia could provide nurses with an effective practice for reducing pain intensity in these patients.
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    Effects of ropivacaine on pain after laparoscopic cholecystectomy: A prospective, randomized study
    (Health Communications Inc, 2007) Sozbilen, Murat; Yeniay, Levent; Unalp, OmerVedat; Makay, Ozer; Pirim, Alihan; Ulukaya, Sezgin; Uyar, Meltem; Ersin, Sinan
    Postoperative pain after laparoscopic cholecystectonny is an ongoing problem. To relieve this pain, practitioners have used many anesthetic and analgesic drugs. This study was undertaken to assess the effects of incisional and intraperitoneal administration of ropivacaine on postoperative pain and stress response in patients undergoing laparoscopic cholecystectomy. In this prospective, singleblinded, randomized study, 45 patients with ASA (American Society of Anesthesiologists) scores I and II who were about to undergo laparoscopic cholecystectomy were divided into 3 groups. After cholecystectomy, a total of 40 mL of 3.75% ropivacaine was administered preincisionally and intraperitoneally to patients in group 1 (n=1 4); preincisionally and intraperitoneally to patients in group 2 (n=1 7); and intraperitoneally and locally at incision sites to patients in group 3 (n=14). Blood levels of epinephrine and norepinephrine were examined preoperatively, 15 min after insufflation, and attheend of the operation. Visual analog pain scale scores and analgesic requirements were used for 24-h postoperative follow-up of pain levels reported by patients. No statistically significant difference was found among the 3 groups with respect to visual analog pain scale scores, total analgesic requirements, and accompanying pain, nausea, and vomiting. The earliest analgesic requirements were seen in group 2 (P <.005), and less shoulder pain was noted in group 3 (P <.005). Norepinephrine and epinephrine levels showed no statistically significant differences between the 3 groups. Administration of ropivacaine preoperatively and postoperatively for laparoscopic cholecystectomy has similar effects on postoperative pain and the stress response of patients.
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    The effects of sufentanil added to low-dose hyperbaric bupivacaine in unilateral spinal anaesthesia for outpatients undergoing knee arthroscopy
    (2014) Sertöz, Nezih; Aysel, İnan; Uyar, Meltem
    Amaç: Bu çalışmada günübirlik diz artroskopisi uygulanan hastalarda düşük doz hiperbarik bupivakaine sufentanil eklenmesinin tek taraflı spinal anesteziye etkilerinin incelenmesi amaçlanmaktadır. Gereç ve Yöntem: 20-50 yaş arasında ASA fiziksel durumu I-II olan ve diz artroskopisi yapılması planlanmış 62 hasta çalışmaya dahil edildi. Hastalar iki gruba randomize edildi. 1 ml %0.5 hiperbarik bupivakain ile unilateral spinal anestezi Grup B’ ye (n=33) ve 0.5ml (2.5µg) sufentanilin 1 ml hiperbarik bupivakaine eklenmesi ile yapılan unilateral spinal anestezi Grup BS’ ye (n=29) uygulandı. Bulgular: İki grup arasında sosyodemografik değişkenler, hemodinamik parametreler, maksimum duysal, sempatik ve motor blok seviyeleri, motor blok çözünme zamanı ve taburculuğa kadar geçen süre açısından istatistiksel anlamlı farklılık gözlenmedi (p>0.05). İki grup arasında iki segment gerileme zamanı (Grup B: 52 dk, Grup BS: 59dk), ambulasyon zamanı (Grup B: 147 dk, Grup BS: 157 dk) ve ürinasyon zamanı (Grup B: 136 dk, Grup BS: 149 dk) açısından istatistiksel anlamlı farklılıklar vardı (p<0.05). Bu çalışmada Grup B’ de kaşıntı gözlenmezken, Grup BS’ de yedi hastada ameliyat sonrası kaşıntı gözlendi (p<0.05). Sonuç: Günübirlik artroskopi uygulanan tüm hastalara taburculuk süresini uzatmaksızın düşük doz hiperbarik bupivakaine sufen- tanil eklenmesi ile tek taraflı spinal anestezi başarıyla uygulanmıştır. Ancak, artroskopi gibi günübirlik girişimlerde, tek başına düşük doz hiperbarik bupivakain uygulamasının da yeterli olduğu sonucuna varılmıştır.
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