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Öğe The Comparison of Reported Ingested Paracetamol Dose with Serum Blood Concentrations and Their Relationship with N-Acetylcysteine Administration: A Retrospective Study of 117 Patients(Galenos Publishing House, 2023) Turan, C.; Yurtseven, A.; Basa, E.G.; Ergin, F.; Uçar, M.; Karakoyun, M.; Saz, E.U.Introduction: We aimed to compare the patient reported ingested and blood paracetamol concentrations (BPC) and to investigate the indications for N-acetylcysteine (NAC) administration in referred patients. Methods: This is a retrospective study of acute paracetamol intoxications (API) at the tertiary paediatric emergency department (ED) between June 2015-June 2019. We evaluated the demographics, cause of intoxications, reported doses (mg/kg), BPCs (8/4/12/16 and/or 24th hours). Indications of antidote usage and referral to ED were accepted as BPC >150 mg/kg. Results: Overall, we reviewed 117 cases of acute API. The mean age was 8.97 (±6.0) years, and 68.3% were female. The reported ingested of paracetamol (RIP) median dose was 2725 mg (mean 138±51.9 mg/kg). Adolescents had a significantly higher RIP than that of younger subjects (p<0.001). BPC was performed in 88.9% of the patients at the 4th, 8th, 12th, 16th and 24th hour in 11.1%, 9.4%, 3.5% and 3.5% of cases, respectively. Although, only 34/66 of the referred cases had a RIP dose >150 mg/kg, physicians at the first healthcare facility tended to administer activated charcoal (90.9%), gastric lavage (68%) and intravenous NAC (48%). The referring healthcare facility physicians-initiated NAC particularly for patients who reported ingesting >150 mg/kg (p=0.001). Conclusion: RIP doses should not be used to determine the need for NAC. The antidote should be used in centres where BPCs are not available or in a group of patients who cannot be transferred to a referral centre within the first eight hours. © 2023, Galenos Publishing House. All rights reserved.Öğe First Report of QoI Resistance in Venturia inaequalis Causing Apple Scab in Apple Orchards in Turkey.(Amer Phytopathological Soc, 2016) Turan, C.; Nanni, I. M.; Tosun, N.; Collina, M.Öğe New Mediterranean Marine biodiversity records (June 2013)(Natl Centre Marine Research, 2013) Siokou, I.; Ates, A. S.; Ayas, D.; Ben Souissi, J.; Chatterjee, T.; Dimiza, M.; Durgham, H.; Dogrammatzi, K.; Erguden, D.; Gerakaris, V.; Grego, M.; Issaris, Y.; Kadis, K.; Katagan, T.; Kapiris, K.; Katsanevakis, S.; Kerkhof, F.; Papastergiadou, E.; Pesic, V.; Polychronidis, L.; Rifi, M.; Salomidi, M.; Sezgin, M.; Triantaphyllou, M.; Tsiamis, K.; Turan, C.; Tziortzis, I.; D'Acoz, C. D'Udekem; Yaglioglu, D.; Zaouali, J.; Zenetos, A.This paper concerns records of species that have extended their distribution in the Mediterranean Sea. The finding of the rare brackish angiosperm Althenia filiformis in the island of Cyprus is interesting since its insertion in the Red Data Book of the Flora of Cyprus is suggested. The following species enriched the flora or fauna lists of the relevant countries: the red alga Sebdenia dichotoma (Greece), the hydrachnid mite Pontarachna adriatica (Slovenia), and the thalassinid Gebiacantha talismani (Turkey). Several alien species were recorded in new Mediterranean localities. The record of the burrowing goby Trypauchen vagina in the North Levantine Sea (Turkish coast), suggests the start of spreading of this Lessepsian immigrant in the Mediterranean Sea. The findings of the following species indicate the extension of their occurrence in the Mediterranean Sea: the foraminifer Amphistegina lobifera (island of Zakynthos, Greece), the medusa Cassiopea andromeda (Syria), the copepod Centropages furcatus (Aegean Sea), the decapod shrimp Melicertus hathor (island of Kastellorizo, Greece), the crab Menoethius monoceros (Gulf of Tunis), the barnacles Balanus trigonus, Megabalanus tintinnabulum, Megabalanus coccopoma and the bivalves Chama asperella, Cucurbitula cymbium (Saronikos Gulf, Greece).Öğe Pediatric cardiac arrest in the emergency department: Outcome is related to the time of admission(Professional Medical Publications, 2019) Yurtseven, A.; Turan, C.; Akarca, F.K.; Saz, E.U.Objectives: Nights and weekends represent a potentially high-risk time for pediatric cardiac arrest (CA) patients in emergency departments. Data regarding night or weekend arrest and its impact on outcomes is controversial. The purpose of this study was to determine the relationship between cardiopulmonary resuscitation during the various emergency department shifts and survival to discharge. Methods: We conducted a retrospective, observational study of patients who had visited our Emergency Department for CAs from January 2014 to December 2016. Medical records and patient characteristics of 67 children with CA were retrieved from patient admission files. Results: The mean age was 54.7±7.3 months and 59% were male. Rates of survival to discharge 35% (11/31) within working hours’ vs. out of working hours 3% (1/36). Among the CAs presenting to the emergency department, the survival rates were higher for working hours than for non-working hours (OR: 37.6 (2.62-539.7), p: 008). The rate of return of spontaneous circulation within working hours was higher than that of non-working hours (71% vs.19%) (p<0.001). Patients who received chest compression for more than 10 minutes had the lowest survival rate (2%) (p<0.001), whereas better outcome was associated with in-hospital CA, younger age (less than 12 months) and respiratory failure. Conclusion: Survival rates from pediatric CAs were significantly lower during non-working hours. Poor outcome was associated with prolonged cardiopulmonary resuscitation, out of hospital CA and older age. © 2019, Professional Medical Publications. All rights reserved.Öğe Suicide attempt management among Turkish and American adolescents: A comparison of two pediatric emergency departments(Turkiye Klinikleri, 2023) Yurtseven, A.; Turan, C.; Ort, D.M.; Islam, M.; Köse, S.; Saz, E.U.; Hennes, H.Background/aim: Suicide is one of the leading causes of death among adolescents. This study aimed to compare the characteristics and short-term outcomes of Turkish and American adolescents with suicide attempts and determine the differences in management and resource utilization between two pediatric emergency departments; one in Türkiye and one in the United States of America. Materials and methods: Adolescents who presented to the emergency departments with a chief complaint of suicide attempt between October 2017 and September 2018 were eligible for including in the study. Characteristics and other information of 217 (131 American and 86 Turkish) suicide attempter adolescents were retrieved from medical records. Outcome was defined as re-admission to the emergency department for another suicide attempt within 3 months of the index visit. Results: Overall, 78% of adolescents were female. Abuse history (physical/sexual) was more common among American adolescents (p = 0.005), whereas uncontrolled psychiatric diseases were more evident in Turkish cases (p < 0.001). Social worker assessment and hospitalization rates were significantly lower, with shorter mean duration of follow-up in the emergency department among Turkish compared to American adolescents (respectively, p < 0.001, p < 0.001 and p = 0.002). Repeated suicide attempts within three months were significantly higher in the Turkish group compared to the American one (29% vs. 8%, p < 0.001). Receiving a social worker assessment, hospitalization and longer observation in emergency department reduced the incidence of repeated suicide attempts (respectively, p <0.001, p = 0.003 and p = 0.012). Conclusion: Turkish adolescents had shorter observation time in the emergency department, received fewer assessment by social workers and were less likely to be hospitalized. These may have contributed to the higher rate of repeat suicide attempts following discharge from the emergency department. Adequate resources are needed to help decrease the burden of suicide among Turkish adolescents. © TÜBİTAK.
