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Öğe Evaluation of serum cystatin-C in dogs with visceral leishmaniasis(Springer, 2009) Pasa, S.; Bayramli, G.; Atasoy, A.; Karul, A.; Ertug, S.; Toz, S. OzensoySerum Cystatin C (sCys-C) is one of the most important serum markers of renal function assessment in dogs. The purpose of this study was to determine the sCys-C concentration in dogs with visceral leishmaniasis (VL). In the study, 16 dogs with VL and 10 clinical healty dogs (control) were used. Mean sCys-C concentration of the infected dogs was significantly higher than that of the control group (p < 0.05). Mean serum creatinine concentration was lower and mean blood urea nitrogen, albumin and globulin concentrations were higher in dogs with VL; however, these changes were not statistically significant. Mean total protein and phosphorus concentrations were found to be higher in dogs with VL than healthy dogs (p < 0.05). No significant correlation had been determined between sCys-C and other variables. Visceral leishmaniasis in dogs has increased sCys-C concentration indicating a possible renal impairment; however, further studies are needed to be performed together with renal biopsies in the investigation sCys-C in dogs with VL.Öğe Evaluation of serum cystatin-C in dogs with visceral leishmaniasis(Springer, 2009) Pasa, S.; Bayramli, G.; Atasoy, A.; Karul, A.; Ertug, S.; Toz, S. OzensoySerum Cystatin C (sCys-C) is one of the most important serum markers of renal function assessment in dogs. The purpose of this study was to determine the sCys-C concentration in dogs with visceral leishmaniasis (VL). In the study, 16 dogs with VL and 10 clinical healty dogs (control) were used. Mean sCys-C concentration of the infected dogs was significantly higher than that of the control group (p < 0.05). Mean serum creatinine concentration was lower and mean blood urea nitrogen, albumin and globulin concentrations were higher in dogs with VL; however, these changes were not statistically significant. Mean total protein and phosphorus concentrations were found to be higher in dogs with VL than healthy dogs (p < 0.05). No significant correlation had been determined between sCys-C and other variables. Visceral leishmaniasis in dogs has increased sCys-C concentration indicating a possible renal impairment; however, further studies are needed to be performed together with renal biopsies in the investigation sCys-C in dogs with VL.Öğe Optimisation of diagnostic real time PCR assays for ITS-1 and ITS-2 regions of Leishmania Genus(Wiley-Blackwell Publishing, Inc, 2009) Toz, S. Ozensoy; Tetik, A.; Ertabaklar, H.; Zeyrek, F. Yildiz; Culha, G.; Ozbel, Y.Öğe Optimisation of diagnostic real time PCR assays for ITS-1 and ITS-2 regions of Leishmania Genus(Wiley-Blackwell Publishing, Inc, 2009) Toz, S. Ozensoy; Tetik, A.; Ertabaklar, H.; Zeyrek, F. Yildiz; Culha, G.; Ozbel, Y.Öğe Possible antileishmanial effect of recombinant human erythropoietin(Wiley-Blackwell Publishing, Inc, 2009) Inceboz, T.; Baskin, H.; Dogan, Y.; Toz, S. Ozensoy; Bahar, I. H.Öğe Possible antileishmanial effect of recombinant human erythropoietin(Wiley-Blackwell Publishing, Inc, 2009) Inceboz, T.; Baskin, H.; Dogan, Y.; Toz, S. Ozensoy; Bahar, I. H.