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Öğe Comparison of the rermineralisation effect of a glass ionomer cement versus a resin composite on dentin of primary teeth(Ariesdue Srl, 2014) Aykut-Yetkiner, A.; Simsek, D.; Eronat, C.; Ciftcioglu, M.Aim The aim of this study was to investigate the interaction of a high viscosity glass ionomer cement (G/C) and a composite resin with caries affected dentin and to determine the remineralization levels. Materials and Methods In a split Mouth deSign 24 GIC and composite resin atraumatic restorative treatment restorations were made in vivo and the teeth were collected after 2 years and subsequently settioned and examined using Vickers microhardness test; the latter was performed starting from the dentin surfate adjacent to the restoration. Repeated Measure ANOVA and Bonferroni Statistical methods were used for data analysis. Results The micrdhardness adjacent to the GIC reStorative material resulted tube significantly higher. Conclusion GIC resulted to be a better restorative material for the remineralization of caries affected dentin, though further studies are necessary for the corroboration of this finding. The GIC restored primary molar dentin had a higher level of remineralizatiOn and GIC could be the material of chdice in pediatric dentistry.Öğe A novel assessment tool for clinical care of patients with autoinflammatory disease: juvenile autoinflammatory disease multidimensional assessment report(Clinical & Exper Rheumatology, 2016) Konukbay, D.; Gattorno, M.; Yildiz, D.; Frenkel, J.; Acikel, C.; Sozeri, B.; Makay, B.; Ayaz, N. Aktay; Barut, K.; Kisaarslan, A.; Bilginer, Y.; Karaman, D.; Peru, H.; Simsek, D.; Aydog, O.; Unsal, E.; Gunduz, Z.; Fidanci, B. E.; Kone-Paut, I.; Kasapcopur, O.; Ravelli, A.; Ozen, S.; Demirkaya, E.Objective. To develop and test a new multidimensional questionnaire for assessment of children with auto-inflammatory disease (AID) such as FMF, PFAPA, HIDS, TRAPS in standard clinical care. Methods. The juvenile auto-inflammatory disease multidimensional assessment report (JAIMAR) includes 16 parent or patient-centered measures and four dimensions that assess functional status, pain, therapeutic compliance and health-related quality of life (physical, social, school, emotional status) with disease outcome. It is proposed for use as both a proxy-report and a patient self report, with the suggested age range of 8-18 years for use as a self-report. Results. 250 children with FMF were included in the study. Total of 179 forms were filled tip by parents and patients, and 71 forms were filled up by parents having children less than 8 years. Completing and scoring the JAIMAR can be done in 15 minutes. For the JAIMAR's dimensions, the Cronbach's alpha coefficient for internal consistency was between 0.507-0.998. There was a significant and a positive correlation between the test-retest scale scores (ICC=0.607-0.966). Concerning construct validity, all factors loadings were above 030. For the criterion validity, the correlation level between each dimension and the related scale ranged from medium (r=0329, p<0.0001) to large (r=0.894, p<0.0001). The parents' proxy-reported and children's self reported data were outstandingly concordant (r=0.770-0.989). Conclusion. The development of the JAIMAR introduces a new and multidimensional approach in paediatric rheumatology practice. It is a new tool for children with auto-inflammatory disease and it may help enhance their quality of care.Öğe POST-AUTHORIZATION SAFETY OF LENALIDOMIDE plus DEXAMETHASONE IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA: EARLY SAFETY REPORT OF TURKISH PASS STUDY(Ferrata Storti Foundation, 2015) Tuglular, A. T. Firatli; Pehlivan, M.; Sari, H. I.; Ayyildiz, M. O.; Saydam, G.; Sonmez, M.; Besisik, S. Kalayoglu; Ozgur, G.; Gurkan, E.; Kaynar, L.; Ali, R.; Ozet, G.; Demirkan, F.; Ongoren, S.; Ozdogu, H.; Gunduz, E.; Tiftik, E. N.; Salim, O.; Turgut, M.; Hacihanefioglu, A.; Ure, U. B.; Ozdemir, E.; Altuntas, F.; Simsek, D.; Ulu, N.; Beksac, M.Öğe POST-AUTHORIZATION SAFETY OF LENALIDOMIDE plus DEXAMETHASONE IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA: EARLY SAFETY REPORT OF TURKISH PASS STUDY(Ferrata Storti Foundation, 2015) Tuglular, A. T. Firatli; Pehlivan, M.; Sari, H. I.; Ayyildiz, M. O.; Saydam, G.; Sonmez, M.; Besisik, S. Kalayoglu; Ozgur, G.; Gurkan, E.; Kaynar, L.; Ali, R.; Ozet, G.; Demirkan, F.; Ongoren, S.; Ozdogu, H.; Gunduz, E.; Tiftik, E. N.; Salim, O.; Turgut, M.; Hacihanefioglu, A.; Ure, U. B.; Ozdemir, E.; Altuntas, F.; Simsek, D.; Ulu, N.; Beksac, M.Öğe POST-AUTHORIZATION SAFETY OF LENALIDOMIDE plus DEXAMETHASONE IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA: EARLY SAFETY REPORT OF TURKISH PASS STUDY(Ferrata Storti Foundation, 2015) Tuglular, A. T. Firatli; Pehlivan, M.; Sari, H. I.; Ayyildiz, M. O.; Saydam, G.; Sonmez, M.; Besisik, S. Kalayoglu; Ozgur, G.; Gurkan, E.; Kaynar, L.; Ali, R.; Ozet, G.; Demirkan, F.; Ongoren, S.; Ozdogu, H.; Gunduz, E.; Tiftik, E. N.; Salim, O.; Turgut, M.; Hacihanefioglu, A.; Ure, U. B.; Ozdemir, E.; Altuntas, F.; Simsek, D.; Ulu, N.; Beksac, M.