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Öğe Central nervous system infections in the absence of cerebrospinal fluid pleocytosis(Elsevier B.V., 2017) Erdem H.; Ozturk-Engin D.; Cag Y.; Senbayrak S.; Inan A.; Kazak E.; Savasci U.; Elaldi N.; Vahaboglu H.; Hasbun R.; Nechifor M.; Tireli H.; Kilicoglu G.; Defres S.; Gulsun S.; Ceran N.; Crisan A.; Johansen I.S.; Namiduru M.; Dayan S.; Kayabas U.; Parlak E.; Khalifa A.; Kursun E.; Sipahi O.R.; Yemisen M.; Akbulut A.; Bitirgen M.; Popovic N.; Kandemir B.; Luca C.; Parlak M.; Stahl J.P.; Pehlivanoglu F.; Simeon S.; Ulu-Kilic A.; Yasar K.; Yilmaz G.; Yilmaz E.; Beovic B.; Catroux M.; Lakatos B.; Sunbul M.; Oncul O.; Alabay S.; Sahin-Horasan E.; Kose S.; Shehata G.; Andre K.; Dragovac G.; Gul H.C.; Karakas A.; Chadapaud S.; Hansmann Y.; Harxhi A.; Kirova V.; Masse-Chabredier I.; Oncu S.; Sener A.; Tekin R.; Deveci O.; Ozkaya H.D.; Karabay O.; Agalar C.; Gencer S.; Karahocagil M.K.; Karsen H.; Kaya S.; Pekok A.U.; Celen M.K.; Deniz S.; Ulug M.; Demirdal T.; Guven T.; Bolukcu S.; Avci M.; Nayman-Alpat S.; Yaşar K.; Pehlivano?lu F.; Ates-Guler S.; Mutlu-Yilmaz E.; Tosun S.; Sirmatel F.; Batirel A.; Öztoprak N.; Kadanali A.; Turgut H.; Baran A.I.; Karaahmetoglu G.; Sunnetcioglu M.; Haykir-Solay A.; Denk A.; Ayaz C.; Gorenek L.; Larsen L.; Poljak M.; Barsic B.; Argemi X.; Sørensen S.M.; Bohr A.L.; Tattevin P.; Gunst J.D.; Baštáková L.; Jereb M.; Johansen I.S.; Chehri M.; Beraud G.; Del Vecchio R.F.; Maresca M.; Yilmaz H.; Sharif-Yakan A.; Kanj S.S.; Korkmaz F.; Komur S.; Coskuner S.A.; Ince N.; Akkoyunlu Y.; Halac G.; Nemli S.A.; Ak O.; Kaya S.; Gunduz A.; Gozel M.G.; Hatipoglu M.; Cicek-Senturk G.; Akcam F.Z.; Inkaya A.C.; Sagmak-Tartar A.; Ersoy Y.; Tuncer-Ertem G.; Balkan I.I.; Cetin B.; Ersoz G.; Ozgunes N.; Yesilkaya A.; Erturk A.; Gundes S.; Turhan V.; Yalci A.; Aydin E.; Diktas H.; Ulcay A.; Seyman D.; Leblebicioglu H.Previous multicenter/multinational studies were evaluated to determine the frequency of the absence of cerebrospinal fluid pleocytosis in patients with central nervous system infections, as well as the clinical impact of this condition. It was found that 18% of neurosyphilis, 7.9% of herpetic meningoencephalitis, 3% of tuberculous meningitis, 1.7% of Brucella meningitis, and 0.2% of pneumococcal meningitis cases did not display cerebrospinal fluid pleocytosis. Most patients were not immunosuppressed. Patients without pleocytosis had a high rate of unfavorable outcomes and thus this condition should not be underestimated. © 2017 The Author(s)Öğe Non-HACEK Gram-negative bacillus endocarditis [Endocardite à bacilles à Gram négatif non HACEK](Elsevier Masson SAS, 2019) Ertugrul Mercan M.; Arslan F.; Ozyavuz Alp S.; Atilla A.; Seyman D.; Guliyeva G.; Kayaaslan B.; Sari S.; Mutay Suntur B.; Isik B.; Mert A.Patients and methods: Retrospective analysis of clinical data using 26 diagnosed non-HACEK Gram-negative infective endocarditis cases from nine hospitals in Turkey. Results: Mean age of patients was 53 (28–84) years, with a 23% case fatality. Nineteen (73%) of the 26 patients had at least one predisposing factor. The presence of a central venous catheter was the most common predisposing factor (7/26 patients). Pseudomonas aeruginosa (7/26 patients) and Escherichia coli (7/26 patients) were the most common pathogens. The median duration of the antibiotic therapy was 42 days (range 3–84 days). Surgical procedures were performed in 10 patients. The case fatality was similar in patients who did or did not undergo surgery (20% vs. 25%). © 2019