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    Effects of Preoperative Gabapentin on Postoperative Pain after Radical Retropubic Prostatectomy
    (Sage Publications Ltd, 2012) Deniz, M. N.; Sertoz, N.; Erhan, E.; Ugur, G.
    OBJECTIVE: The impact of preoperative gabapentin on tramadol consumption using patient-controlled analgesia (PCA) and postoperative pain was assessed in patients undergoing radical retropubic prostatectomy (RRP). METHODS: In this prospective, randomized trial, 51 patients undergoing RRP were randomized into two groups: the gabapentin group received 900 mg gabapentin orally 2 h before surgery; the control group did not receive gabapentin. Postoperative analgesia was provided by tramadol PCA. Pain was assessed using a visual analogue scale for, 24 h, postoperatively. RESULTS: Mean cumulative tramadol consumption at 24 h was comparable in the two groups. Pain scores at 45 min, 60 min and 2 h postoperatively, and the number of patients who required rescue analgesia, were significantly lower in the gabapentin group than in the control group. Side-effects were similar in the two groups. CONCLUSIONS: Preoperative administration of 900 mg gabapentin did not decrease tramadol consumption, but was associated with lower pain scores in the early postoperative phase and a reduced need for rescue analgesia, compared with controls, in patients undergoing RRP.
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    Evaluation of The Analgesic Effect of Caudal Anesthesia In Pediatric Lower Extremity Orthopedic Surgery
    (Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Duşmez, A.; Sargın, A.; Sahutoglu, C.; Sertoz, N.; Balcıoğlu, T.
    The aim of this study is to evaluate the preoperative and postoperative effects of caudal analgesia in pediatric orthopedic lower extremity surgery. A total of 92 children who underwent lower extremity osteotomy under general anesthesia were included in the study retrospectively. For caudal analgesia, 0.5 ml/kg 0.25% levobupivacaine a nd 20 mcg/kg morphine were used routinely. The effect of caudal analgesia on hemodynamic parameters (heart rate, mean arterial pressure, oxygen saturation, sevoflurane concentration) and procedural success rates were evaluated using objective pain scale s cores (OPS). The mean age of the patients was 5.6±3.7 (1-13) years, and 54.3% of them were male. The mean operation time was 100±94 minutes. Side effects (nausea-vomiting) were detected in 12% of the cases. Caudal block suppressed the response to the surgical incision, and caused a decrease i n heart rate, mean arterial pressure, and sevoflurane values (p <0.05). The OPS’s were found to be ? 5 in 8.7% of the patients, and in these patients’ caudal block was considered to be unsuccessful for achieving a satisfactory analgesic effect. The time to the first analgesic administration to the patients was 526 ± 242 (85-1110) minutes after caudal analgesia. In the first 24 hours, 40.2% of the patients did not need additional analgesics. Caudal block is an anesthesia technique with high success rate, eas y application, and low complication rate. In addition, it can provide long-term analgesia both peri operatively and postoperatively in pediatric patients undergoing subumblical surgery with a single injection technique. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.