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Öğe THE SEROPREVALENCE OF HEPATITIS A IN ADULTS IN IZMIR: PRIOR TO INTRODUCING VACCINE INTO ROUTINE VACCINATION PROGRAM(Nobel Ilac, 2013) Kose, Sukran; Mandiracioglu, Aliye; Cavdar, Gulsun; Ulu, Yildiz; Nohutcu, Nese; Gurbuz, Ilhan; Sariavci, Senol; Ozkan, MehmetObjective: Hepatitis A virus (HAV) is an important public health problem in Turkey. This study was aimed to determine the population-based seroprevalence of HAV in Izmir. Material and Method: In this cross-sectional study, a representative sample of the population, which was at the age of 5 years, was selected by using random stratification method. A total of 2156 healthy subjects participated in this present study Blood specimens were collected for testing anti-HAV IgG, and were examined by using enzyme-linked immunosorbent assay (ELISA). A questionnaire was also administered to obtain data regarding demographic characteristics and living conditions of the participants. Results: Anti-HAV IgG positivity was 93.9%. It was found that anti-HAV IgG seropositivity was higher in the subjects with lower income levels, lower education status, at older age, whereas it was lower in younger an(d) single subjects. Conclusion: Improved water and food sanitation resulted in reduced seroprevalence of HAV at younger age groups in Izmir.Öğe Seroprevalence of varicella-zoster virus in the prevaccine era: A population-based study in Izmir, Turkey(Elsevier Science London, 2013) Kose, Sukran; Mandiracioglu, Aliye; Senger, Suheyla Serin; Ulu, Yildiz; Cavdar, Gulsun; Gol, Basak; Gurbuz, Ilhan; Sariavci, Senol; Nohutcu, NesePurpose: To determine the population-based seroprevalence of varicella zoster virus (VZV) and related risk factors in Izmir. Materials and methods: A population-based household survey was conducted. A representative sample of the population older than 15 years of age was selected using multistage random sampling. A total of 2136 healthy persons participated in this cross-sectional study. The participants completed a questionnaire designed to collect data related to socio-demographic characteristics and risk factors. Blood samples were collected, and VZV-specific IgG was measured using an ELISA. Results: In total, 94.3% of individuals were seropositive for VZV. The difference between VZV seroprevalence in urban and rural populations was significant (OR: 2.6 (95% CI, 1.7-3.8)). No statistically significant differences in seropositivity were observed with respect to other sociodemographic characteristics. Conclusion: A large proportion of the participants were found to be immune to VZV. (C) 2012 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.