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Öğe Alzheimer tipi demansta kraniyal MRG volumetrik inceleme(Ege Üniversitesi, 2009) Polat, Fatma; Kumral, EmreBu çalışmada Alzheimer hastalarında, demans tanısında kullanılan nöropsikolojik testlerle, Kraniyal MRG volumetrik ölçümleri karşılaştırılmış, nöropsikolojik performans ile beyin volüm ölçümleri arasındaki ilişki incelenerek, en iyi ölçüm metodu ortaya konmaya çalışılmıştır. Bu amaçla 27 kontrol, 35 Alzheimer hastasına nöropsikolojik testler ve kraniyal MRG volumetrik ölçüm uygulanmıştır. Daha sonra kranial MRG incelemeleri SPM (statistical parametric mapping) ile değerlendirilmiştir. Normal olgularla, Alzheimer hastaları arasında testlerdeki performans puanları ile Kranial MRG volumetrik ölçümleri arasında anlamlı farklılıklar saptanmıştır. Çalışmaya alınan olguların kognitif bozukluk düzeyi ile Kranial MRG volumetrik ölçümleri arasında ters yönde bir ilişki olduğu gözlenmiştir. Yaptığımız çalışmada nöropsikolojik performans ile gri madde kaybı arasında en fazla ilişki olduğu gösterildi. SPM analizinde AH’larındaki nöropatolojik tutulum ile uyumlu bulgular elde edildi. Gri madde atrofisi ile nöropsikolojik performans arasındaki ilişki ve SPM analizinin AH tanısını koymadaki doğruluğu gösterildi. Sonuç olarak çalışmamızda kullandığımız SPM analizi ve gri madde atrofisinin AH erken tanısı ve prognozunda belirleyici olabileceği, tedaviye yanıtın belirlenmesi açısından gelecek çalışmalar için yararlı bir yöntem olacağı düşünülmektedir.Öğe Clinical features of benign paroxysmal positional vertigo in western Turkey(Karger, 2008) Celebisoy, Nese; Polat, Fatma; Akyuerekli, OenderBackground: It was the aim of this study to analyze the clinical manifestations, the incidence of each variant and the comorbid conditions of benign paroxysmal positional vertigo (BPPV) as well as the response to treatment. Methods: One hundred and fifty-seven patients with BPPV were reviewed prospectively. An extensive neurotologic examination was performed. All patients were treated with an appropriate canalith repositioning maneuver (CRM). Results: In 138 patients, the posterior canal (PC) was involved, in 14 patients, the horizontal canal (HC), in 2 patients, the anterior canal (AC), and in 3 patients, both the PC and HC. A history of head trauma was identified in 17 patients. In 1 patient sensorineural hearing loss on the affected side and in another bilateral peripheral vestibular loss was present. A history of migraine was reported in 21 cases. A resolution attributable to the first CRM was achieved in 132 patients. Conclusions: PC involvement was the most frequent type constituting 87.9% of all BPPV cases. HC, AC and mixed canal types were relatively rare constituting 8.9, 1.3 and 1.9% of the cases, respectively. Response to the first CRM was recorded in 84.1%. Association with migraine was recorded in 13.4% of the patients. Copyright (c) 2008 S. Karger AG, Basel.Öğe Music and Brain: Preservation of Singing in an Aphasic Patient(Galenos Yayincilik, 2013) Polat, Fatma; Yuceyar, Nur; Calli, Cem; Yuntem, Nilgun; Colakoglu, ZaferPreservation of ability to sing in the presence of severe expressive aphasia has been known for a long time, Based on lesion studies, it is generally proposed that the right hemisphere is dominant especially for melody production. We present a 50-year-old woman with non-fluent aphasia due to left hemisphere acute infarction. If the first part of the melody was given by the examiner, she was able to sing a familiar song with text words without any musical error, where she was unable to speak the same words. 3T functional magnetic resonance imaging showed bilateral anterior temporal, bilateral mesencephalic and right deep temporal activation during the task of singing a familiar song. Hemispheric domain specificity and cerebral network in musical processing will be discussed on the basis of our findings and recent neuroimaging studies. We also emphasize that music therapies may facilitate recovery in such non-fluent aphasic patients.Öğe Music and Brain: Preservation of Singing in an Aphasic Patient(Galenos Yayincilik, 2013) Polat, Fatma; Yuceyar, Nur; Calli, Cem; Yuntem, Nilgun; Colakoglu, ZaferPreservation of ability to sing in the presence of severe expressive aphasia has been known for a long time, Based on lesion studies, it is generally proposed that the right hemisphere is dominant especially for melody production. We present a 50-year-old woman with non-fluent aphasia due to left hemisphere acute infarction. If the first part of the melody was given by the examiner, she was able to sing a familiar song with text words without any musical error, where she was unable to speak the same words. 3T functional magnetic resonance imaging showed bilateral anterior temporal, bilateral mesencephalic and right deep temporal activation during the task of singing a familiar song. Hemispheric domain specificity and cerebral network in musical processing will be discussed on the basis of our findings and recent neuroimaging studies. We also emphasize that music therapies may facilitate recovery in such non-fluent aphasic patients.
