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    GIANT CELL REPARATIVE GRANULOMA ASSOCIATED WITH MANDIBULAR FRACTURE IN AN ELDERLY EDENTULOUS PATIENT: CASE REPORT
    (Gunes Kitabevi Ltd Sti, 2017) Ozden Yuce, Meltem; Solmaz, Murat Cihan; Ozveri Koyuncu, Banu; Turk, Gozde; Gunbay, Tayfun
    Giant cell reparative granuloma (GCRG) is a benign reactive intraosseous tumour in the head and neck region, characterized by the presence of multi-nucleated giant cells. It often arises in the first 3 decades of life, with a peak in the second and third decades. However initial presentation of GCRG in elderly patients is rare. The majority of patients are asymptomatic and, in some patients, the lesions are incidentally discovered during radiologic examinations. Presentation with pathologic fractures is rare. The treatment of GCRG is usually surgical, but treatment procedures vary depending on the case. The case reported here describes an elderly edentulous female with a pathologic fracture in the anterior mandibular region. Attention has been focused on the dental findings by computed tomography and surgical treatment of GCRG.
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    Guided bone regeneration simultaneous with implant placement using bovine-derived xenograft with and without liquid platelet-rich fibrin: a randomized controlled clinical trial
    (Springer Heidelberg, 2021) Isik, Gozde; Ozden Yuce, Meltem; Kocak-Topbas, Nazan; Gunbay, Tayfun
    Objective To assess augmentation success after guided bone regeneration (GBR) carried out simultaneously with implant placement using bovine-derived xenograft alone and in combination with liquid platelet-rich fibrin (liquid-PRF). Methods This randomized controlled clinical trial was conducted on patients with horizontal bone deficiency in the posterior regions of the mandible. After implant placement, GBR procedures were randomly performed using liquid-PRF-enriched bovine-derived xenograft (for the test group) and with bovine-derived xenograft alone (for the control group). To assess the change in augmentation thickness, the primary outcome of the study, cone beam computed tomography was carried out at the implant sites on completion and 6 months after surgery. The secondary outcomes were marginal bone level and implant survival rate at prosthetic delivery and at 6 months, 1 year, and 2 years follow-up after loading. The significance level was set at pResults Twenty patients with 50 implants were analyzed for the test group and 20 patients with 48 implants for the control group. At 6 months postoperatively, the mean values of augmentation thickness were 1.63 +/- 0.21 mm, 2.59 +/- 0.34 mm, and 3.11 +/- 0.36 mm for the test group and 1.34 +/- 0.14 mm, 2.49 +/- 0.24 mm, and 2.97 +/- 0.24 mm for the control group at 2 mm, 4 mm, and 6 mm below to the implant shoulder (p < 0.001, p = 0.007, and p = 0.036, respectively). The mean marginal bone loss was found to be less than 1 mm for both study groups during the 2 years of follow-up after prosthetic loading. Implant survival rate was 100% for both study groups. Conclusion Bovine-derived xenograft alone and in combination with liquid-PRF are both successful in achieving bone augmentation around the implants and produce a small change in marginal bone level and a high implant survival rate after loading.
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    Treatment decision for impacted mandibular third molars: Effects of cone-beam computed tomography and level of surgeons' experience
    (Public Library of Science, 2024) Adali, Emine; Ozden Yuce, Meltem; Isik, Gozde; Sener, Elif; Mert, Ali
    The aim of this study was to analyse the effect of surgeons' experience and the benefit of using cone-beam computed tomography (CBCT) images, compared to the use of panoramic radiography (PAN) images, on their decisions with regard to mandibular third molar treatment modality. Panoramic radiographs and CBCTs from a total of 143 patients who had undergone impacted third molar surgery were randomly evaluated for treatment decision by 10 participants with differing clinical experience (5 novices and 5 experienced surgeons). The degree of agreement between the same type of participants was 'Substantial Agreement' (0.61-0.80) or 'Almost Perfect' (0.81-1.00). When the treatment modality decisions of the experienced and novice surgeons, using PAN and CBCT images, were compared, a statistically significant difference was found (p<0.01) between the variables. In 50 cases, experienced surgeons decided from CBCT images that total extraction was the best treatment method but opted for coronectomy when presented with PAN images of the same cases. In 164 cases novice surgeons decided on total extraction from CBCT images but chose coronectomy when presented with PAN images of the same cases. The results obtained from this study revealed that the degree of professional experience of the surgeon was a significant factor in determining the treatment decision. Moreover, the treatment choice of experienced surgeons was less affected by the change in imaging technique employed, when compared to novice surgeons.