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    Effect of metabolic control on cognitive functions in children and adolescents with type 1 diabetes mellitus
    (Walter De Gruyter Gmbh, 2023) Kar, Seyma; Er, Eren; Ata, Aysun; Inal-Kaleli, Ipek; Ozcan, Tugce; Kose, Sezen; Ozbaran, Burcu
    Objectives: Neurocognitive functions of children with type 1 diabetes mellitus (T1D) are reported to be poorer than those of healthy peers. The aim was to investigate the effects of age of onset of diabetes, metabolic control, and type of insulin regimen on neurocognitive functions in children and adolescents with T1D.Methods: Forty-seven children aged 6-18 years, with T1D for at least five years, were included. Children with a known psychiatric disorder or chronic diseases other than T1D were excluded. Intelligence via the Wechsler children's intelligence scale (WISC-R), short-term memory via the audio-auditory digits form B (GISD-B) test, visual motor perception via the Bender Gestalt test, and attention via the Moxo continuous attention and performance test, timing, hyperactivity, and impulsivity (Moxo-dCPT) were assessed.Results: Compared with the T1D group, healthy controls had higher scores in terms of verbal intelligence quotient (IQ), performance IQ, and total IQ mean scores on WISC-R (p=0.01, p=0.05 and p=0.01, respectively). On the MOXO-dCPT test, the T1D group had higher impulsivity compared to the control group (p=0.04). Verbal IQ was better in the moderate control group than in the poorer metabolic control (p=0.01). Patients with no history of diabetic ketoacidosis (DKA) had higher performance, verbal and total intelligence scores than the group with history of DKA.Conclusions: Poor metabolic control and a history of DKA in children with T1D adversely affected neurocognitive functions. It would be beneficial to consider the assessment of neurocognitive functions in T1D and to take the necessary precautions in follow-up.
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    Evaluation of the Cases who Applied to University Hospital Child and Adolescent Mental Health Committee Because of Sexual Abuse
    (Galenos Publ House, 2021) Pilan, Birsen Senturk; Erermis, Serpil; Ozcan, Tugce; Calisan, Reyhan; Barankoglu, Ilayda; Kaya, Ahsen; Senol, Ender
    Objective: The aim of this study was to examine the sociodemographic characteristics, psychiatric diagnoses and factors associated with psychiatric diagnoses of children and adolescents who are victims of sexual abuse. Method: The files of 92 children and adolescents aged between 0-18 who were referred to University Hospital Child and Adolescent Psychiatry Forensic Policlinic between January 2017 and December 2019 due to sexual abuse were evaluated retrospectively. Psychiatric diagnoses of the cases were made according to DSM 5 diagnostic criteria. Intellectual capacity of the cases was evaluated according to the latest verison of Wechsler Intelligence Scale for Children. Results: In our study, 78 (84.8%) cases were female and 14 (15.2%) were male. Mean age of the cases was 14.1 +/- 3.88 years. The most common type of sexual abuse was touching (52.2%, n=48). There was a psychiatric diagnose in 50 (54.3%) of them. The most common psychiatric diagnoses were posttraumatic stress disorder (n=29, 31.5%) and major depressive disorder (n=25, 27.2%). The rate of psychiatric diagnosis was significantly higher in cases exposed to coercion and violence (p=0.032). In 32 cases (34.8%), it was determined that the abuser was within the family. Conclusion: Sexual abuse has an effect on child's development throughout life.In our study, the rate of psychiatric diagnosis was high. It is very important to provide the necessary psychiatric support to the victims of sexual abuse. With the studies to be done in this area, awareness can be increased and necessary precautions can be taken.
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    Is aripiprazole a key to unlock anorexia nervosa?: A case series
    (Wiley, 2020) Tahillioglu, Akin; Ozcan, Tugce; Yuksel, Gamze; Majroh, Noorjahan; Kose, Sezen; Ozbaran, Burcu
    Aripiprazole contributes an increase in body mass index and attenuation in anorexia nervosa (AN) symptoms, leading clinical improvements with lower side-effect profile; but it is not enough to cure comorbid depressive symptoms in AN.
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    Psychiatric view for disorders of sex development a 12-year experience of a multidisciplinary team in a university hospital
    (Walter De Gruyter Gmbh, 2020) Pilan, Birsen Senturk; Ozbaran, Burcu; Celik, Didem; Ozcan, Tugce; Ozen, Samim; Goksen, Damla; Ulman, Ibrahim
    Background: Psychiatric consultation is important in the follow-up of disorders of sex development (DSD) patients. in this study, we aimed to present the 12-year psychiatric follow-up data of the patients who were referred by Ege University Medical Faculty DSD Multidisciplinary Team and followed up in Child and Adolescent Psychiatry. Methods: Psychiatric data of 118 patients, who were followed by the DSD multidisciplinary team between 2007 and 2019, were reviewed retrospectively. the psychiatric diagnoses of the patients were evaluated according to semi-structured interview form Schedule for Affective Disorders and Schizophrenia for School-Age Children/ Present and Lifetime Turkish Version. Results: the mean age of the 118 cases was 13.21 years (+/- 7.18). Endocrine diagnoses of the cases were 46 XX DSD in 35 (29.6%), 46 XY DSD in 81 (68.7%), and chromosome disorders in 2 (1.7%). There was at least psychiatric diagnosis in 36 (30.5%) cases. the most common psychiatric diagnosis was attention deficit and hyperactivity disorder (ADHD) (n=18, 15.3%). ADHD was most common in congenital adrenal hyperplasia (n =4, 22.4%) and androgen synthesis defects (ASD) (n= 4, 22.4%); depression was most common in complete gonadal dysgenesis and ASD n=3, 23.1%); and mental retardation was most common in ASD (n = 3, 37.5%). Conclusions: in order to provide a healthy perspective for cases with DSD, it is important to make a psychiatric evaluation and to share observations and clinical findings in regular team meetings.
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    Quality of Life and Psychological Well-being in Children and Adolescents with Disorders of Sex Development
    (Galenos Yayincilik, 2021) Pilan, Birsen Senturk; Ozbaran, Burcu; Celik, Didem; Ozcan, Tugce; Ozen, Samim; Goksen, Damla; Cogulu, Ozgur
    Objective: The aim of this study was to assess the quality of life (QoL) and psychological well-being in child and adolescent with disorders of sex development (DSD). Methods: Sixty-two cases, aged 2-18 years, who were followed by a multidisciplinary DSD team were included. All participants and their parents were requested the complete the Pediatric Quality of Life Inventory (PedsQL) and the Strengths and Difficulties Questionnaire. The psychiatric diagnoses of the patients were evaluated according to Schedule for Affective Disorders and Schizophrenia for School-Age Children/Present and Lifetime Turkish Version. Results: There was no significant difference between the 46,XX DSD and 46,XY DSD groups for both child and parent in Total PedsQL score. in the subscale scores, the PedsQL Physical Functionality Score reported by children was significantly lower for the 46,XX DSD group than for the 46,XY DSD group (p=0.01). There was a psychiatric diagnosis in 25.8% of cases. The PedsQL School Functionality Score reported by children in the group with psychiatric diagnosis was significantly lower than the group without psychiatric diagnosis (p=0.018). in the group with psychiatric diagnosis, the PedsQL Total Score and the subscale scores (Emotional Functionality Score, Social Functionality Score, School Functionality) reported by parents were significantly lower than in parents of the group without psychiatric diagnosis. Conclusion: This study emphasized that psychiatric disorders in DSD patients negatively affect the QoL. Psychiatric support and counseling from a multidisciplinary team are very important for families affected by DSD.
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    Telemental Health Assessment of Adolescents During the COVID-19 Pandemic: A Follow-up Study
    (Galenos Publ House, 2023) Pilan, Birsen Senturk; Kaleli, Ipek Inal; Cek, Didem; Ozcan, Tugce; Azizov, Faig; Huseynova, Samira; Cengiz, Gizem
    Aim: This study aimed to understand how the pandemic has affected the mental health of adolescents with a previous psychiatric diagnosis.Materials and Methods: Fifty-nine patients aged 12-18 years who had been previously followed up in the adolescent mental health unit were included in this study. The participants were interviewed via telephone between June-July, 2020 and December, 2020-January 2021. Their socio-demographic data, psychiatric diagnoses and the previous Clinical Global Impression (CGI) scores were obtained from the patient files. The clinical global follow-up scale was scored by the interviewing physician.Results: Past CGI scores before the pandemic were significantly greater for those participants with more than one psychiatric condition (p=0.024). For those participants with more than one psychiatric condition, the difference between the CGI scores prior to the pandemic and during the early stages of the pandemic were significant (p=0.004). The total satisfaction scores for telepsychiatry services assessed via the telemedicine evaluation form were statistically higher for those participants with a single psychiatric disorder (p=0.023). The past and early pandemic CGI scores were found to be inversely correlated with the telemedicine evaluation form with r=-0.338, p=0.019, r=-0.353 p=0.014, respectively. Conclusion: The present study offers a perspective for adolescent mental health during the pandemic, underlining the importance and caveats of healthcare delivery to the youth with mental health problems during lockdown.