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    Huge craniopharyngioma: diffusion MRI and contrast-enhanced FLAIR imaging
    (Pergamon-Elsevier Science Ltd, 2002) Sener, RN; Dzelzite, S; Migals, A
    Craniopharyngiomas are most commonly located extraaxially in the suprasellar area. They are benign but aggressive neoplasms. An adult patient is reported to have a huge craniopharyngioma with gross extensions to the surroundings. In diffusion MRI, it had high signal for b = 1000 mm(2)/s (true diffusion) images, and at the same time, high ADC values 2.12 and 2.27 x 10(-3) mm(2)/s, compared to that of normal cerebellar parenchyma 0.85 x 10(-3) mm(2)/s). In FLAIR images, obtained after administration of intravenous contrast medium, an-intense, diffuse enhancement pattern was seen involving the viable tumor portions as well as the intratumoral fluid. (C) 2002 Elsevier Science Ltd. All rights reserved.
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    Prominent myelin vacuolization in neurofibromatosis type 2
    (Elsevier Science Inc, 2003) Sener, RN; Dzelzite, S; Migals, A; Raits, U; Veinbergs, AA
    Myelin vacuolization has previously been documented by MRI with histopathologic correlation in patients with neurofibromatosis type 1. This paper presents a patient with neurofibromatosis type 2 with MRI findings consistent with a prominent form of myelin vacuolization, unilaterally involving the right thalamus, globus pallidus and substantia nigra. On MRI, they appeared as multiple nodular-ovoid structures with a layered configuration. They were hypointense on T1-weighted, and FLAIR images, and hyperintense on T2-weighted images. On the apparent diffusion coefficient (ADC) map of an echo-planar diffusion imaging sequence, their ADC value ranged between 1.98 and 2.27 x 10(-3) mm(2)/s, a value higher than that of normal cerebral parenchyma, less than that of CSF. (C) 2002 Elsevier Science Inc. All rights reserved.
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    Prominent myelin vacuolization in neurofibromatosis type 2
    (Elsevier Science Inc, 2003) Sener, RN; Dzelzite, S; Migals, A; Raits, U; Veinbergs, AA
    Myelin vacuolization has previously been documented by MRI with histopathologic correlation in patients with neurofibromatosis type 1. This paper presents a patient with neurofibromatosis type 2 with MRI findings consistent with a prominent form of myelin vacuolization, unilaterally involving the right thalamus, globus pallidus and substantia nigra. On MRI, they appeared as multiple nodular-ovoid structures with a layered configuration. They were hypointense on T1-weighted, and FLAIR images, and hyperintense on T2-weighted images. On the apparent diffusion coefficient (ADC) map of an echo-planar diffusion imaging sequence, their ADC value ranged between 1.98 and 2.27 x 10(-3) mm(2)/s, a value higher than that of normal cerebral parenchyma, less than that of CSF. (C) 2002 Elsevier Science Inc. All rights reserved.