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    Epidemiology of adult food allergies in turkey: A multicenter study
    (Wiley, 2020) Pasaoglu, Karakis G.; Kurt, E.; Atayik, E.; Koca, I; Koycu, G.; Oner, Erkekol F.; Mungan, D.
    [No abstract available]
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    A multi-institutional evaluation of carboplatin plus docetaxel combination in elderly patients with advanced gastric cancer
    (Imprimatur Publications, 2013) Kurt, E.; Cubukcu, E.; Karabulut, B.; Olmez, O. F.; Kurt, M.; Avci, N.; Ozdemir, F.; Tunali, D.; Evrensel, T.; Manavoglu, O.
    Purpose: Albeit the majority of gastric cancers occur at advanced age, little is known regarding the optimal systemic treatment of elderly patients with advanced gastric cancer (AGC). Methods: Patients with AGC who were >= 65 years old and were treated with carboplatin (area under the curve/AUG 5, on day 1, every 3 weeks) plus docetaxel (75 mg/m(2), on day 1, every 3 weeks) at 3 institutions were included in this retrospective analysis. The efficacy and the safety data of the regimen were analyzed. Results: A total of 30 patients were enrolled. They received 128 cycles of chemotherapy, with a median of 4 cycles (range 2-8). Complete response (CR) and partial response (PR) were observed in 2 (6.7%) and 10 patients (33.3%), respectively, amounting to an overall objective response rate (ORR) of 40%. Seven patients (23.3%) had disease stabilization (SD), and 11(36.7%) showed disease progression (PD). The most common grade 3-4 toxicity was neutropenia occurring in 19 patients (63.3%). The mean progression-free survival (PFS) was 6.0 +/- 0.5 months (95% CI: 5.0-7.4), and the mean overall survival (OS) 12.0 +/- 1.0 months (95% CI: 9.2-12.1). Conclusion: Carboplatin plus docetaxel seems to be an active and well-tolerated regimen, representing a valuable alternative to cisplatin- and/or fluoropyrimidine-containing regimens for the treatment of elderly patients with AGC.
  • Küçük Resim Yok
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    A multi-institutional evaluation of carboplatin plus docetaxel combination in elderly patients with advanced gastric cancer
    (Imprimatur Publications, 2013) Kurt, E.; Cubukcu, E.; Karabulut, B.; Olmez, O. F.; Kurt, M.; Avci, N.; Ozdemir, F.; Tunali, D.; Evrensel, T.; Manavoglu, O.
    Purpose: Albeit the majority of gastric cancers occur at advanced age, little is known regarding the optimal systemic treatment of elderly patients with advanced gastric cancer (AGC). Methods: Patients with AGC who were >= 65 years old and were treated with carboplatin (area under the curve/AUG 5, on day 1, every 3 weeks) plus docetaxel (75 mg/m(2), on day 1, every 3 weeks) at 3 institutions were included in this retrospective analysis. The efficacy and the safety data of the regimen were analyzed. Results: A total of 30 patients were enrolled. They received 128 cycles of chemotherapy, with a median of 4 cycles (range 2-8). Complete response (CR) and partial response (PR) were observed in 2 (6.7%) and 10 patients (33.3%), respectively, amounting to an overall objective response rate (ORR) of 40%. Seven patients (23.3%) had disease stabilization (SD), and 11(36.7%) showed disease progression (PD). The most common grade 3-4 toxicity was neutropenia occurring in 19 patients (63.3%). The mean progression-free survival (PFS) was 6.0 +/- 0.5 months (95% CI: 5.0-7.4), and the mean overall survival (OS) 12.0 +/- 1.0 months (95% CI: 9.2-12.1). Conclusion: Carboplatin plus docetaxel seems to be an active and well-tolerated regimen, representing a valuable alternative to cisplatin- and/or fluoropyrimidine-containing regimens for the treatment of elderly patients with AGC.
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    National occupational allergy and respiratory diseases awareness survey results
    (Wiley-Blackwell, 2014) Kalpaklioglu, A. F.; Baccioglu, A.; Kurt, E.; Sener, O.; Goksel, O.; Canbakan, S.