Yazar "Korkmaz C." seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Familial Mediterranean Fever (FMF) in Turkey: Results of a nationwide multicenter study
    (Lippincott Williams and Wilkins, 2005) Tunca M.; Ozdogan H.; Kasapcopur O.; Yalcinkaya F.; Tutar E.; Topaloglu R.; Yilmaz E.; Arici M.; Bakkaloglu A.; Besbas N.; Akpolat T.; Dinc A.; Erken E.; Tirpan K.; Ozer H.T.E.; Soyturk M.; Senturk T.; Balci B.; Ozguc M.; Dundar M.; Akar E.; Ozel D.; Dundar M.; Gunesacar R.; Booth D.R.; Hawkins P.N.; Touitou I.; Aksentijevich I.; Matzner Y.; Arslan S.; Balaban Y.; Batman F.; Bayraktar Y.; Apras S.; Calguneri M.; Duzova A.; Kav T.; Ozaltin F.; Simsek H.; Sivri B.; Tatar G.; Akkoc N.; Kavukcu S.; Soylu A.; Turkmen M.; Unsal E.; Arisoy N.; Caliskan S.; Gogus F.; Masatlioglu S.; Sever L.; Akkok N.; Cakar N.; Kara N.; Kocak H.; Ozalp S.; Bilge I.; Sevinc E.; Gul A.; Kamali S.; Sadikoglu B.; Selcukbiricik F.; Sirin A.; Sucu A.; Bek K.; Bulbul M.; Delibas A.; Demircin G.; Erdogan O.; Oner A.; Mesiha M.; Ozkaya N.; Tekin M.; Demirkaya E.; Erdem H.; Gok F.; Pay S.; Islek I.; Kabasakal Y.; Keser G.; Ozmen M.; Akoglu E.; Atagunduz P.; Direskeneli H.; Temel M.; Tuglular S.; Buyan N.; Bakkaloglu S.; Derici U.; Goker B.; Kalman S.; Ozkaya O.; Dusunsel R.; Gunduz Z.; Poyrazoglu M.H.; Korkmaz C.; Baskin E.; Koseoglu H.K.; Saatci U.; Yucel E.; Coban E.; Yakupoglu G.; Oktem F.; Tunc E.; Cobankara V.
    Familial Mediterranean fever (FMF) is an autosomal recessive disease that is prevalent among eastern Mediterranean populations, mainly non-Ashkenazi Jews, Armenians, Turks, and Arabs. Since a large proportion of all the FMF patients in the world live in Turkey, the Turkish FMF Study Group (FMF-TR) was founded to develop a patient registry database and analyze demographic, clinical, and genetic features. The cohort was composed of 2838 patients (mean age, 23.0 ± 13.33 yr; range, 2-87 yr), with a male:female ratio of 1.2:1. There was a mean period of 6.9 ± 7.65 years from disease onset to diagnosis; the period was about 2 years shorter for each decade since 1981. Ninety-four percent of patients were living in the central-western parts of the country; however, their familial origins (70% from the central-eastern and Black Sea regions) reflected not only the ongoing east to west migration, but also the historical roots of FMF in Turkey. Patients' clinical features included peritonitis (93.7%), fever (92.5%), arthritis (47.4%), pleuritis (31.2%), myalgia (39.6%), and erysipelas-like erythema (20.9%). Arthritis, arthralgia, myalgia, and erysipelas-like erythema were significantly more frequent (p < 0.001) among patients with disease onset before the age of 18 years. Genetic analysis of 1090 patients revealed that M694V was the most frequent mutation (51.4%), followed by M680I (14.4%) and V726A (8.6%). Patients with the M694V/M694V genotype were found to have an earlier age of onset and higher frequencies of arthritis and arthralgia compared with the other groups (both p < 0.001). In contrast to other reported studies, there was no correlation between amyloidosis and M694V homozygosity in this cohort. However, amyloidosis was still remarkably frequent in our patients (12.9%), and it was prevalent (27.8%) even among the 18 patients with a disease onset after age 40 years. Twenty-two patients (0.8%) had nonamyloid glomerular diseases. The high prevalence of vasculitides (0.9% for polyarteritis nodosa and 2.7% for Henoch-Schönlein purpura) and high frequency of pericarditis (1.4%) were striking findings in the cohort. Phenotype II cases (those patients with amyloidosis as the presenting or only manifestation of disease) were rare (0.3% or less). There was a high rate of a past diagnosis of acute rheumatic fever, which suggested a possible misdiagnosis in children with FMF presenting with recurrent arthritis. To our knowledge, this is the largest series of patients with FMF reported from 1 country. We describe the features of the disease in the Turkish population and show that amyloidosis is still a substantial problem.
  • Küçük Resim Yok
    Öğe
    A review of the economics and the marketing of the pomegranate industry in Turkey
    (International Society for Horticultural Science, 2015) Isík Özguven A.; Gültekin U.; Gozlekci S.; Yílmaz I.; Yílmaz C.; Kücük E.; Imrak B.; Korkmaz C.
    Turkey is one of the most important agricultural countries in the word, being endowed with a wide range of ecological conditions. Therefore, many species of fruits and vegetables are produced in Turkey. Pomegranate is widely distributed in the Mediterranean and Aegean regions of Turkey, even if its world-wide trade is still limited. According to the latest numbers of TurkStat statistics, it is obvious that pomegranate is one of the promising crops in Turkey. Total planted area of pomegranates is rising very fast and the number of bearing and non-bearing trees reached to around 16 million in 2012. Total production increased from 60.000 to 315.000 tons starting from the year 2000 to 2012, and the country is one of the world's important pomegranate export countries. In addition to this, degree of pomegranate self-sufficiency is about 150% in Turkey. Since Turkish domestic market in fresh fruit and the juice industry are increasing and there is steady growth of consumption, pomegranate can be considered one of the leading agroindustrial crops in the near future in Turkey. There are more than 40 brands of about 37 producer companies (17 of them are dealing with pomegranates) in the country. Fruit processed in the Turkish juice industry is about 983.000 tons in total (pomegranates is 118.000 tons) in 2011.