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Öğe Clinical and Laboratory Findings of SARS-CoV-2 Infection in Children Younger than 6 Months Old: Neutropenia is More Common Not Lymphopenia(Oxford Univ Press, 2022) Ozenen, Gizem Guner; Bal, Zumrut Sahbudak; Bilen, Nimet Melis; Arslan, Sema Yildirim; Ak, Gunes; Koc, Gonca; Cicek, CandanBackground Studies on age-related differences in clinical and laboratory features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited. We aimed to evaluate the demographic, clinical, laboratory findings of SARS-CoV-2 infection in children younger than 6 months old and compare them with older children. Methods A single-center retrospective study, including 209 confirmed SARS-CoV-2 infection cases, was conducted between 11 March 2020 and 1 September 2021. The case group consisted of 47 patients younger than 6 months old, whereas the control group consisted of 162 patients older than 6 months old. Results The mean age of the case group was 2.77 +/- 1.52 months, and the control group was 101.89 +/- 65.77 months. Cough was statistically higher in the control group, and poor feeding was higher in the case group (p = 0.043, 0.010). The underlying disease rate was statistically higher in the control group; however, the hospitalization rate was higher in the case group (p = 0.036, 0.001). The case group had significantly lower median values of the absolute neutrophil count, hemoglobin and higher median values of white blood cell, absolute lymphocyte count and platelet than the control group (p < 0.05). C-reactive protein, fibrinogen values were significantly lower, and procalcitonin, D-dimer, troponin T, N-terminal pro-B-type natriuretic peptide significantly higher in the case group (p < 0.05). Lymphopenia was more common in the control group, whereas neutropenia was more common in the case group (p = 0.001, 0.011). Conclusions We showed that most children younger than 6 months old had mild and asymptomatic SARS-CoV-2 infection; however, the hospitalization rate was higher, and neutropenia was more common in older children. Lay summary Studies on age-related differences in clinical and laboratory features on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients are limited. We aimed to evaluate the demographic, clinical and laboratory findings of SARS-CoV-2 infection in children younger than 6 months old and compare them with older children. A single-center retrospective study was conducted, including 209 SARS-CoV-2 infection cases. The case group consisted of 47 patients younger than 6 months old, and the control group consisted of 162 patients older than 6 months old. Most children younger than 6 months old had mild and asymptomatic SARS-CoV-2 infection; however, the hospitalization rate was higher than older children. Neutropenia was more common in patients younger than 6 months than older children with SARS-CoV-2 infection, even if underlying diseases were excluded.Öğe Diagnostic Dilemma in a Patient with Central Precocious Puberty: Ovarian Steroid Cell Tumor(Karger, 2021) Balki, Hanife Gul; Ata, Aysun; Karayazili, Ayse Merve; Serin, Gurdeniz; Koc, Gonca; Ozdemir, Necmettin; Celik, Ahmet[No Abstract Available]Öğe Persistent pulmonary mass-like lung consolidations and chest wall extension in a newborn diagnosed with chronic granulomatous disease(Ma Healthcare Ltd, 2022) Ekizalioglu, Duygu D.; Ozek, Gulcihan; Aygun, Ayse; Ozturk, Gokcen K.; Koc, Gonca[No Abstract Available]Öğe Prevalence of cervical extension of the thymus in children(Elsevier Sci Ltd, 2022) Koc, Gonca; Esmat, Habib Ahmad; Coskun, MehmetBackground: The cervical extension of the thymus is the most common variation. However, this may be mistaken for a soft tissue mass in the neck particularly by the radiologists who are not familiar with the pediatric population and not aware of this variation, leading to unnecessary surgery and increased medical costs. Since the rates of cervicaly extended thymus in children in clinical practice are lacking in Turkey, this study aimed to evaluate the prevalence of cervical extension of the normal thymus in the pediatric population. Materials and methods: This descriptive cross-sectional study included all pediatric patients who were referred to the radiology department for neck ultrasonography between August-October 2018. A high-frequency probe was implemented and 220 patients (152 male, 68 female) with a mean age of 8.7 +/- 4.39 years (ranging from 1 month to 18 years of age) were examined. Results: Cervical extension of the thymus was detected in 103 patients (46.8%). The age of the patients was found to be significantly lower than the age of the patients whose thymus was not extended (7.87 +/- 4.15 years and 9.59 +/- 4.46 years, respectively. p = 0.006). The mean craniocaudal length of the thymus that cervically extended was 6.41 +/- 2.31 mm. There was no significant difference in the length of the thymus between males, females (6.48 +/- 2.12 mm and 6.37 +/- 2.46 mm. p = 0.924), and different age groups (p = 0.442). Conclusions: Approximately half of the children have the cervical extension of the thymus. Thus, radiologists and clinicians should be aware of this entity to avoid unnecessary imaging studies and interventional procedures.Öğe A rare pediatric case with radiological findings: pelvic cystic schwannoma(2021) Karabulut, Ahmat Kasım; Koc, Gonca; Divarcı, Emre; Naghiyev, Javid; Savas, RecepSchwannomas are peripheral nerve sheath tumors usually detected in adults which are extremely rare in pediatric population and when present they are commonly associated with Neurofibromatosis type 2. While frequently observed in the head, neck, and extremities, they could be detected anywhere in the body including abdominal cavity. The most common site for intraabdominal schwannomas is stomach and pelvic schwannomas are extremely rare. The imaging characteristics are quite diverse, and they could seldom be pure cystic. Herein, we describe a case in the pediatric age group diagnosed with pelvic cystic schwannoma.
