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Assessment of the requisites of microbiology based infectious disease training under the pressure of consultation needs
(2011) Erdem H.; Tekin-Koruk S.; Koruk I.; Tozlu-Keten D.; Ulu-Kilic A.; Oncul O.; Guner R.; Birengel S.; Mert G.; Nayman-Alpat S.; Eren-Tulek N.; Demirdal T.; Elaldi N.; Ataman-Hatipoglu C.; Yilmaz E.; Mete B.; Kurtaran B.; Ceran N.; Karabay O.; Inan D.; Cengiz M.; Sacar S.; Yucesoy-Dede B.; Yilmaz S.; Agalar C.; Bayindir Y.; Alpay Y.; Tosun S.; Yilmaz H.; Bodur H.; Erdem H.A.; Dikici N.; Dizbay M.; Oncu S.; Sezak N.; Sari T.; Sipahi O.R.; Uysal S.; Yeniiz E.; Kaya S.; Ulcay A.; Kurt H.; Besirbellioglu B.A.; Vahaboglu H.; Tasova Y.; Usluer G.; Arman D.; Diktas H.; Ulusoy S.; Leblebicioglu H.
Background: Training of infectious disease (ID) specialists is structured on classical clinical microbiology training in Turkey and ID specialists work as clinical microbiologists at the same time. Hence, this study aimed to determine the clinical skills and knowledge required by clinical microbiologists.Methods: A cross-sectional study was carried out between June 1, 2010 and September 15, 2010 in 32 ID departments in Turkey. Only patients hospitalized and followed up in the ID departments between January-June 2010 who required consultation with other disciplines were included.Results: A total of 605 patients undergoing 1343 consultations were included, with pulmonology, neurology, cardiology, gastroenterology, nephrology, dermatology, haematology, and endocrinology being the most frequent consultation specialties. The consultation patterns were quite similar and were not affected by either the nature of infections or the critical clinical status of ID patients.Conclusions: The results of our study show that certain internal medicine subdisciplines such as pulmonology, neurology and dermatology appear to be the principal clinical requisites in the training of ID specialists, rather than internal medicine as a whole. © 2011 Erdem et al; licensee BioMed Central Ltd.
Central nervous system infections in the absence of cerebrospinal fluid pleocytosis
(Elsevier B.V., 2017) Erdem H.; Ozturk-Engin D.; Cag Y.; Senbayrak S.; Inan A.; Kazak E.; Savasci U.; Elaldi N.; Vahaboglu H.; Hasbun R.; Nechifor M.; Tireli H.; Kilicoglu G.; Defres S.; Gulsun S.; Ceran N.; Crisan A.; Johansen I.S.; Namiduru M.; Dayan S.; Kayabas U.; Parlak E.; Khalifa A.; Kursun E.; Sipahi O.R.; Yemisen M.; Akbulut A.; Bitirgen M.; Popovic N.; Kandemir B.; Luca C.; Parlak M.; Stahl J.P.; Pehlivanoglu F.; Simeon S.; Ulu-Kilic A.; Yasar K.; Yilmaz G.; Yilmaz E.; Beovic B.; Catroux M.; Lakatos B.; Sunbul M.; Oncul O.; Alabay S.; Sahin-Horasan E.; Kose S.; Shehata G.; Andre K.; Dragovac G.; Gul H.C.; Karakas A.; Chadapaud S.; Hansmann Y.; Harxhi A.; Kirova V.; Masse-Chabredier I.; Oncu S.; Sener A.; Tekin R.; Deveci O.; Ozkaya H.D.; Karabay O.; Agalar C.; Gencer S.; Karahocagil M.K.; Karsen H.; Kaya S.; Pekok A.U.; Celen M.K.; Deniz S.; Ulug M.; Demirdal T.; Guven T.; Bolukcu S.; Avci M.; Nayman-Alpat S.; Yaşar K.; Pehlivano?lu F.; Ates-Guler S.; Mutlu-Yilmaz E.; Tosun S.; Sirmatel F.; Batirel A.; Öztoprak N.; Kadanali A.; Turgut H.; Baran A.I.; Karaahmetoglu G.; Sunnetcioglu M.; Haykir-Solay A.; Denk A.; Ayaz C.; Gorenek L.; Larsen L.; Poljak M.; Barsic B.; Argemi X.; Sørensen S.M.; Bohr A.L.; Tattevin P.; Gunst J.D.; Baštáková L.; Jereb M.; Johansen I.S.; Chehri M.; Beraud G.; Del Vecchio R.F.; Maresca M.; Yilmaz H.; Sharif-Yakan A.; Kanj S.S.; Korkmaz F.; Komur S.; Coskuner S.A.; Ince N.; Akkoyunlu Y.; Halac G.; Nemli S.A.; Ak O.; Kaya S.; Gunduz A.; Gozel M.G.; Hatipoglu M.; Cicek-Senturk G.; Akcam F.Z.; Inkaya A.C.; Sagmak-Tartar A.; Ersoy Y.; Tuncer-Ertem G.; Balkan I.I.; Cetin B.; Ersoz G.; Ozgunes N.; Yesilkaya A.; Erturk A.; Gundes S.; Turhan V.; Yalci A.; Aydin E.; Diktas H.; Ulcay A.; Seyman D.; Leblebicioglu H.
Previous multicenter/multinational studies were evaluated to determine the frequency of the absence of cerebrospinal fluid pleocytosis in patients with central nervous system infections, as well as the clinical impact of this condition. It was found that 18% of neurosyphilis, 7.9% of herpetic meningoencephalitis, 3% of tuberculous meningitis, 1.7% of Brucella meningitis, and 0.2% of pneumococcal meningitis cases did not display cerebrospinal fluid pleocytosis. Most patients were not immunosuppressed. Patients without pleocytosis had a high rate of unfavorable outcomes and thus this condition should not be underestimated. © 2017 The Author(s)
The course of spinal tuberculosis (Pott disease): Results of the multinational, multicentre Backbone-2 study
(Elsevier B.V., 2015) Batirel A.; Erdem H.; Sengoz G.; Pehlivanoglu F.; Ramosaco E.; Gülsün S.; Tekin R.; Mete B.; Balkan I.I.; Sevgi D.Y.; Giannitsioti E.; Fragou A.; Kaya S.; Cetin B.; Oktenoglu T.; Celik A.D.; Karaca B.; Horasan E.S.; Ulug M.; Senbayrak S.; Kaya S.; Arslanalp E.; Hasbun R.; Ates-Guler S.; Willke A.; Senol S.; Inan D.; Güclü E.; Ertem G.T.; Koc M.M.; Tasbakan M.; Ocal G.; Kocagoz S.; Kusoglu H.; Güven T.; Baran A.I.; Dede B.; Karadag F.Y.; Yilmaz H.; Aslan G.; Al-Gallad D.A.; Cesur S.; El-Sokkary R.; Sirmatel F.; Savasci U.; Karaahmetoglu G.; Vahaboglu H.
We aimed to describe clinical, laboratory, diagnostic and therapeutic features of spinal tuberculosis (ST), also known as Pott disease. A total of 314 patients with ST from 35 centres in Turkey, Egypt, Albania and Greece were included. Median duration from initial symptoms to the time of diagnosis was 78 days. The most common complications presented before diagnosis were abscesses (69%), neurologic deficits (40%), spinal instability (21%) and spinal deformity (16%). Lumbar (56%), thoracic (49%) and thoracolumbar (13%) vertebrae were the most commonly involved sites of infection. Although 51% of the patients had multiple levels of vertebral involvement, 8% had noncontiguous involvement of multiple vertebral bodies. The causative agent was identified in 41% of cases. Histopathologic examination was performed in 200 patients (64%), and 74% were consistent with tuberculosis. Medical treatment alone was implemented in 103 patients (33%), while 211 patients (67%) underwent diagnostic and/or therapeutic surgical intervention. Ten percent of the patients required more than one surgical intervention. Mortality occurred in 7 patients (2%), and 77 (25%) developed sequelae. The distribution of the posttreatment sequelae were as follows: 11% kyphosis, 6% Gibbus deformity, 5% scoliosis, 5% paraparesis, 5% paraplegia and 4% loss of sensation. Older age, presence of neurologic deficit and spinal deformity were predictors of unfavourable outcome. ST results in significant morbidity as a result of its insidious course and delayed diagnosis because of diagnostic and therapeutic challenges. ST should be considered in the differential diagnosis of patients with vertebral osteomyelitis, especially in tuberculosis-endemic regions. Early establishment of definitive aetiologic diagnosis and appropriate treatment are of paramount importance to prevent development of sequelae. © 2015 European Society of Clinical Microbiology and Infectious Diseases.
Determination of veterinary drug residues in sea water, sediment, and natural fish in the aegean sea
(Parlar Scientific Publications, 2014) Baydan E.; Kaya S.; Cagirgan H.; Yildirim E.; Altintas L.; Yurdakok B.; Ekici H.; Aydin F.G.; Kucukosmanoglu A.G.
In this research, residues of certain veterinary drugs (florfenicol (FF) and florfenicol amine (FFA)) were screened in natural fish, sediment, and seawater samples of the Aegean Sea, while only chloramphenicol (CAP) was searched for in the sediment. Samples were collected from fish farming cages in selected coordinates (Bodrum, Salihli Region, Turkey) on September, October 2011 and March, April 2012. Method: validation and analyses were carried out by HPLC method. For FF; LOD values were 25.11 ppb for sea water, 27.07 ppb for sediment as well as 38.16 and 37.95 ppb for Mullus barbatus and Oblada melanura fish samples. FFA value for Mullus barbatus was 39.60 ppb, respectively. For CAP in sediment samples, LOD values were found as 53.59 ppb. In 4 different sampling areas (A, B, C, D), the lowest temperature was recorded as 14 °C in March 2012 but the highest was 28.3 °C in October 2011; the lowest dissolved oxygen (mg/L) values were detected in March 2012 (from 6.05 to 6.44), the highest in October 2011 (10.78-11.55). The pH values slightly varied month by month; the lowest was 7.9 and the highest 8.6. This research revealed that dissolved oxygen and pH values of the collected seawater samples were in accordance with the normal limits of the offshore seawater values; no significant residue of the analyzed veterinary drugs was found to be present, and all values were found to be lower than LOD values in the sampled fish farms. In conclusion; there was no pollution caused by veterinary drugs. © by PSP.
Elimination of Multi-drug Resistant Acinetobacter baumannii Strain with Various Porphyrin Derivatives Stimulated by Red Light [Çeşitli Porfirin Türevlerinin Kirmizi Işik ile Uyarilarak Çoklu İlaç Dirençli Acinetobacter baumannii Suşunun Yok Edilmesi]
(Institute of Electrical and Electronics Engineers Inc., 2018) Akbiyik A.; Taşli H.; Topaloglu N.; Alptüzün V.; Parlar S.; Kaya S.
In the study, it was aimed to investigate the photoinactivation effect of antimicrobial photodynamic therapy (aPDT) performed on in-vitro conditions with cationic-porphyrin derivatives (CPDs) on multidrug resistant (MDR) A. baumannii. In aPDT experiments using different photosensitizer concentrations and different energy densities, the reduction in bacterial survival reached to > 6 log10 values. aPDT carried out with CPDs at concentrations below the minimum inhibitory concentration (MIC) values has the potential to display a strong antimicrobial activity against the MDR A. baumannii clinical isolate. © 2018 IEEE.
Fundamental characterization of asphalt clay nanocomposites
(2013) Nazzal M.D.; Kaya S.; Gunay T.; Ahmedzade P.
This study aims at characterizing the nanostructure and microstructure and the mechanical behavior of asphalt clay nanocomposites. To this end, various atomic force microscopy (AFM) techniques (i.e., tapping mode imaging, force spectroscopy, and nanoindentation) and X-ray diffraction (XRD) experiments were conducted on asphalt binders modified with different contents of a nanoclay material. The AFM images and XRD results indicated that the nanoclay had an exfoliated structure within the nanocomposite. In addition, the AFM images showed better interaction between the nanoclay layers and the distinct asphalt domains containing the so-called "beelike" structures as compared to the flat asphalt matrix. The results of the force spectroscopy experiments indicated that the inclusion of the nanoclay material significantly enhanced the adhesive forces of asphalt materials, while it had a slightly adverse effect on the cohesive forces. Furthermore, the nanoclay material improved the stiffness and hardness of the asphalt binder measured in the indentation tests. However, this enhancement was affected by the temperature and nanoclay percentage. The results of this study suggest that the mechanical behavior of the asphalt clay nanocomposite can be explained by the formation of a rigid percolating network consisting of the exfoliated nanoclay layers and the fractal asphaltene aggregates in the asphalt binder. The onset of the rigidity percolation appears to be dependent on the effective radius of the asphaltene aggregates and the spacing between the nanoclay layers, a conclusion that may require further experimentation to validate. © 2013 American Society of Civil Engineers.
Impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Hand Hygiene Approach, over 8 years, in 11 cities of Turkey
(SAGE Publications Ltd, 2015) Leblebicioglu H.; Koksal I.; Rosenthal V.D.; Akan Ö.A.; Özgültekin A.; Kendirli T.; Erben N.; Yalcin A.N.; Ulusoy S.; Sirmatel F.; Ozdemir D.; Alp E.; Yıldızdaş D.; Esen S.; Ulger F.; Dilek A.; Yilmaz H.; Yylmaz G.; Kaya S.; Ulusoy H.; Tulunay M.; Oral M.; Ünal N.; Turan G.; Akgün N.; İnan A.; Ince E.; Karbuz A.; Çiftçi E.; Taşyapar N.; Güneş M.; Ozgunes I.; Usluer G.; Turhan O.; Gunay N.; Gumus E.; Dursun O.; Arda B.; Bacakoglu F.; Cengiz M.; Yilmaz L.; Geyik M.F.; Şahin A.; Erdogan S.; Kılıc A.U.; Horoz O.O.
Aims: To evaluate the effectiveness of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Hand Hygiene Approach in Turkey and analyse predictors of poor hand hygiene compliance. Design: An observational, prospective, interventional, before-and-after study was conducted from August 2003 to August 2011 in 12 intensive care units (ICU) of 12 hospitals in 11 cities. The study was divided into a baseline and a follow-up period and included random 30-minute observations for hand hygiene compliance in ICU. The hand hygiene approach included administrative support, supplies availability, education and training, reminders in the workplace, process surveillance, and performance feedback. Results: We observed 21,145 opportunities for hand hygiene. Overall hand hygiene compliance increased from 28.8% to 91% (95% CI 87.6–93.0, p 0.0001). Multivariate and univariate analyses showed that several variables were significantly associated with poor hand hygiene compliance: males vs. females (39% vs. 48%; 95% CI 0.79–0.84, p 0.0001), ancillary staff vs. physicians (35% vs. 46%, 95% CI 0.73–0.78, p 0.0001), and adult vs. pediatric ICUs (42% vs. 74%, 95% CI 0.54–0.60, p 0.0001). Conclusions: Adherence to hand hygiene was significantly increased with the INICC Hand Hygiene Approach. Specific programmes should be directed to improve hand hygiene in variables found to be predictors of poor hand hygiene compliance. © 2014, © The Author(s) 2014.
Investigation of some veterinary drug residues in sea water, sediment, and wild fishes captured around fish farms in the Aegean Sea: Oxytetracyline, ivermectin and emamectin [Ege Denizinde balık çiftlikleri etrafında avlanan doğal ortam balıkları ile çevredeki su ve sedimentin bazı veteriner ilaç kalıntıları yönünden incelenmesi: Oksitetrasiklin, ivermektin ve emamektin]
(Chartered Inst. of Building Services Engineers, 2015) Baydan E.; Kaya S.; Çağirgan H.; Yildirim E.; Altintaş L.; Yurdakök B.; Ekİcİ H.; Aydin F.G.; Küçükosmanoğlu A.G.
Veterinary drug residues and their metabolites in food are regularly investigated by local authorities; however their fate in the environment is still unknown. Despite the importance of the aquaculture industry and the widespread use of antibiotics; limited scientific information regarding their residue in natural fish, sediment and sea water are available in TURKEY. The current study; which is the first study in this area, was undertaken to determine the oxytetracycline (OTC), ivermectin (IVM) and emamectin benzoate (EMA) residues from samples of wild fishes (Oblada melanura, Mullus barbatus), sea water and sediment collected in four different months, caught around the fish cages near Salihli Island in Bodrum, Aegean Sea. Samples were analyzed by High Pressure Liquid Chromatography (HPLC) followed by the validation for each matrix. No residues were found to be above the Limit of detection (LOD) levels of the validated methods in the screened samples. In order to understand the possible risk of veterinary antibiotics, especially for low dose accumulation, to the ecosystem for sustainable aquaculture, conduction of more screening analysis with expanded possible matrices would be beneficial. © 2015 Chartered Inst. of Building Services Engineers. All rights reserved.
Investigation of the presence of autoantibodies in patients with toxocariasis [Toksokarlazisll hastalarda otoantlkor varliginin araştirilmasi]
(2009) Kaya S.; Demlrcl M.; Çetin E.S.; Aridogan B.C.; Şahln M.; Taş T.; Korkmaz M.
Immunopathologic reactions may occur during toxocariasis due to tissue invasion and destruction by the secretions of larvae containing various enzymes with broad spectrum. The aim of this study was to search for autoantibodies such as anti-nuclear (ANA), anti-mitochondrial (AMA), anti-smooth muscle (ASMA), anti-neutrophil cytoplasmic (ANCA), anti-myeloperoxidase (MPO) and liver-kidney microsomal type 1 (LKM-1) antibodies in patients with toxocariasis, in order to investigate the role of toxocariasis as a trigger factor for autoimmune reactions. Forty patients (22 were male; mean age: 35.6 ± 10.7 years) diagnosed as toxocariasis by clinical findings (abdominal pain, allergic symptoms and/or eosinophilia, without detection of any other causative agents, and without liver dysfunction, diabetes mellitus, cardiac or renal failure, and autoimmune disease) and in-house ELISA positivity and 32 healthy controls (16 were male; mean age: 40.7 ± 11.2 years) were included to the study. ANA (screen), dsDNA, SS-A, SS-B, Scl-70, LKM-1, MPO and M2 autoantibodies have been investigated by ELISA (Euroimmun, Germany), while ANCA, AMA and ASMA antibodies by indirect immunofluorescence (IMMCO, NY) methods. Autoantibody positivity was detected in 18 (45%) patients of whom 11 yielded a single type, and 7 yielded ? 2 types of autoantibodies. This rate was 12.5% for control group (two subjects were positive for ANA-Screen, one for anti-M2 and one for anti-LKM-1). The difference between the total positivity rates in patient and control groups was found statistically significant (x2= 5.72, p= 0.004). The most frequent autoantibody type among patients were ASMA (n= 6), followed by anti-dsDNA (n= 5), anti-M2 (n= 5), anti-SS-B (n= 4), anti-LKM-1 (n= 3), anti-SS-A (n= 2), ANCA (n= 2) and anti-MPO (n= 1). Positivity rate for ASMA was found statistically significant in patients' group compared to controls (x 2= 12.24, p= 0.03), while there was no significant difference between the groups in terms of other autoantibody rates (p> 0.05). These data could be related to the possible release of autoantigens following muscle tissue injury during toxocariasis and/or antigenic mimicry of parasitic products during the infection in which muscle invasion is frequently seen. In conclusion, since autoantibodies are frequently detected in toxocariasis, this situation should be taken into consideration in the presence of autoantibodies.
A novel biosensor based on glucose oxidase for activity determination of ?-amylase
(2011) Altug C.; Mengulluoglu U.; Kurt E.; Kaya S.; Dinckaya E.
A glucose oxidase-based biosensor was developed for the determination of ?-amylase activity. The determination method is based on monitoring the decrease in dissolved oxygen concentration related to the starch concentration, for which starch gives a reaction with ?-amylase. Optimization parameters, including glucose oxidase amount, gelatin amount, and glutaraldehyde percentage for cross-linking, were investigated. The effects of pH, buffer system, and temperature on the biosensor system were also investigated. The biosensor had a linear relation to ?-amylase activity and good measurement correlation between 0.66 and 9.83 U/ml. In sample analysis studies, ?-amylase activity in baker's yeast was determined by the biosensor. © 2011 Informa Healthcare USA, Inc.
The place and the efficacy of infectious disease consultations in the hospitals
(2012) Erdem H.; Kurtaran B.; Arun O.; Ylmaz H.; Çelebi G.; Özkaya H.D.; Kaya S.; Birengel S.; Güner R.; Demiroglu Y.Z.; Demirdal T.; Tekin-Koruk S.; Coşkun O.; Kazak E.; Çelen M.K.; Akova M.; Timurkaynak F.; Alpay Y.; Yilmaz E.; Saçar S.; Aydin A.F.; Bodur H.; Elald N.; Inal A.S.; Saba R.; Tok D.; Agalar C.; Candevir A.; Parlak M.; Sipahi O.R.; Yilmaz G.; Koçak N.; Öncü S.; Sirmatel F.; Küçükardali Y.; Güzel-Tunçcan O.; Mete B.; Doyuk-Kartal E.; Ulcay A.; Şenol E.; Dayan S.; Leblebicioglu H.; Tabak F.; Gorenek L.; Ulusoy S.; Ayaz C.; Ergonul O.; Aksu H.S.Z.
Our study aims to determine the efficacy of infectious disease consultations and the interrelations between doctors in this social laboratory. This study was conducted at 34 centers located in 22 cities across Turkey and contributed by 210 infectious disease specialists (IDSs) and 970 non-infectious disease specialists (NIDSs), totaling 1180 medical doctors. Infectious disease specialists and NIDSs have separately contributed by responding to questionnaires designed specifically for the consultation process. It appears that a satisfactory collaboration has been established between IDSs and NIDSs during the consultation practices. There are some discrepancies in the perceptions of some of the NIDSs. These are the evaluation of patients holistically, the expectation of NIDSs in critical infection cases to start the therapy immediately, losing the support of drug companies by NIDSs, and the restriction of NIDSs in routine medical practice. On the other hand, NIDSs seem to have real problems in the diagnosis or treatment of infectious diseases. The consultation service provided by the IDSs in Turkey is widely accepted among other clinicians and appears to be of a crucial importance. Copyright © 2012 by Lippincott Williams & Wilkins.
Seroepidemiological investigation of toxocariasis in the is-parta Region of Turkey
(2010) Demirc M.; Kaya S.; Çetin E.S.; Aridogan B.C.; Önal S.; Korkmaz M.
Background: Toxocariasis is a common disease around the world. Our objective was to determine Toxocara seroprevalence in humans in the city of Isparta, Southwest Turkey, in respect of some determinants such as age, socio-economic level, residence in city center or rural area etc. Methods: Five hundred and thirty four individual participants from Isparta center and 85 from Asagi Gokdere village were included in the study. T. cati specific antibodies were analyzed using excretory-secretory (ES)-enzyme-linked immunosorbent assay (ELISA) method. Results: T. cati antibodies were detected as positive in 73 (13.6%) of 534 samples which were collected from subjects living in the city center and 24 (28.2%) of 85 samples from Asagi Gokdere village. Toxocara seropositivity was detected among 15.6% of whole study group. The seroprevalence of toxocariasis was significantly higher among subjects from village than in subjects from city center (P=0.001). While gender, high school education, source of the water which is used, family income and geophagia/eating nail behaviors were the features which were detected as being associated with toxocariasis seropositivity (odds ratios=0.5; 6.52; 3.61; 0.43; 0.13 respectively), owning dogs or cats and hand washing were detected as being not associated with toxocariasis seropositivity (P > 0.05). Furthermore, Toxocara seropositivity was significantly higher among subjects in 0-10 than >40 year-old group (P=0.02).Conclusion: It can be suggested that untreated lost pet population, environmental contamination, and way of life have influence on the epidemiology of toxocariasis.
Seroepidemiological study of toxocariasis among volunteers animal husbandry workers and veterinary in southern Anatolia in Turkey in 2014
(Tehran University of Medical Sciences (TUMS), 2015) Sozen H.; Citil B.E.; Caylak S.; Gokmen A.A.; Kaya S.; Demirci M.; Korkmaz M.; Sahin C.; Kirli I.
Background: Human toxocariasis is a parasitic infection caused by the larvae of Toxocara canis. We examine the Toxocara seroprevalance in veterinarians and animal husbandry workers living in the Mugla Province, Turkey to evaluate better the risk factors for Toxocara exposure. Methods: In 2014, 376 volunteers participated in the study in 2014. All blood specimens were tested using a commercial enzyme immunoassay kit and ELISA positive samples were confirmed by Western Blot (WB) method. Results: The seroprevalence of Toxocara, as determined by WB, was 8%. A statistically significant correlation was evident between patient age and Toxocara positivity among animal husbandry workers (P = 0.029). A strong association was also evident between sex and seropositivity in the animal husbandry group (P=0.024). Veterinarians working in pet clinics did in fact exhibit higher Toxocara seropositivities relative to those of other groups (P = 0.029). A statistically significant difference was detected between the rural geographic areas surveyed (P = 0.04). Conclusion: In Mugla Province, seroprevalence of Toxocara is lower than other regions. Despite the low seroprevalence observed, especially in high risk professions toxocariasis remains an important medical concern within the region. © 2015, Tehran University of Medical Sciences (TUMS). All rights Reserved.

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