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Öğe Association of Age, Sex, and Heart Failure Etiology in Continuous Flow Left Ventricular Assist Device Patients(Elsevier Inc., 2023) Balcioglu, O.; Kahraman, Ü.; Ergi, D.G.; Karaca, S.; Engin, C.; Yagdi, T.Background: Advanced heart failure studies demonstrate that ischemic factors increase in prevalence with age and are more prominent in men. Ejection fraction (EF) cannot be preserved in these patients, and ischemic cardiomyopathy develops. Non-ischemic factors are more prominent in female heart failure patients, where the EF is preserved. Although an age-associated increase in the rate of heart failure is acknowledged in both sexes, etiologic classifications by sex-based age groups are still lacking. This study examined the etiology of heart failure according to age and sex in ventricular assist device patients. Methods: The patient population included 457 end-stage heart failure patients who received a continuous flow–left ventricular assist device at Ege University Hospital between 2010 and 2017. Age, sex, and cardiomyopathy etiology data were obtained from the hospital database. The Mann-Whitney U test was applied to test the statistical significance among subgroups (95% CI, P <.05 for statistical significance). Results: The prevalence of ischemic cardiomyopathy was significantly lower in male patients aged 18 to 39 years compared to older patients. Conversely, no difference was seen among female patients. The prevalence of dilated cardiomyopathy was higher in male patients who were 18 to 39 years of age compared to older patients, but no difference was present among the female patients. Conclusions: Age and heart failure etiology were demonstrated to be interrelated in men but not in women. The fact that etiologic factors of advanced heart failure in women have a wider range than in men makes the current classification systems insufficient for use in female populations. © 2023 Elsevier Inc.Öğe Crizotinib Efficacy in ALK-Positive Advanced Stage Non-Small Cell Lung Cancer Patients: A Real-World Experience from Turkey(Elsevier Science Inc, 2018) Kilickap, S.; Ozturk, A.; Karadurmus, N.; Korkmaz, T.; Yumuk, P.; Cicin, I.; Paydas, S.; Cilbir, E.; Sakalar, T.; Uysal, M.; Uskent, N.; Demir, N.; Sakin, A.; Turhal, N.; Keskin, S.; Tural, D.; Eralp, Y.; Basal, F.; Yasar, H.; Sendur, M. A.; Demirci, U.; Cubukcu, E.; Karaagac, M.; Karaca, S.; Tatli, A.; Yetisyigit, T.; Urvay, S.; Gursoy, P.; Uluc, B. Oyan; Turna, Z.; Kucukoner, M.; Olmez, O.; Cabuk, D.; Seker, M.; Unal, O.; Meydan, N.; Okutur, S.; Tunali, D.Öğe Mid-term results of combined medical and popliteal artery endarterectomy treatment in Buerger's disease(Turkish National Vascular and Endovascular Surgery Society, 2023) Kahraman, U.; Karaca, S.; Islamoglu, K.; Engin, A.Y.; Islamoglu, F.Aim: Our aim in this article is to present the mid-term results of the best preoperative and postoperative medical treatment and analgesia treatment in patients with advanced Buerger's disease who underwent saphenous patchplasty and saphenous distal bypass after endarterectomy to the popliteal artery or trifurcation area. Material and Methods: Between 2015 and 2023, we operated on 83 patients, diagnosed with Buerger's disease, who were in the chronic stage of the disease, and whose advanced imaging was performed. Preoperative, postoperative, and 1st year control evaluations were determined according to Rutherford, Fontaine classification, and Ankle-Brachial Indexes. Medical treatments of the patients were organized by the vascular surgery team and algology department. After determining the surgical approach strategy according to the imaging of the patients, saphenous patchplasty and anatomical bypass were performed. Results: The mean preoperative ankle-brachial index was 0.305, the mean postoperative ankle-brachial index was 0.644, and the mean 1-year ankle-brachial index was 0.629 in 83 patients included in the study. Statistically significant improvements were observed in the Rutherford and Fontaine classifications. (p-value < 0,001) Amputation was performed in 9.6% of patients within 1 year. Conclusion: Good clinical results and limb salvage can be achieved with a combined medical and surgical treatment approach in advancedstage patients who do not respond despite optimal medical treatment. Provided that patients quit smoking, good determination of the target surgical site, Saphenous patchplasty, and Saphenous distal bypass applied after endarterectomy in suitable patients are supported with good medical and analgesia treatment, the results will improve further. © 2023, Turkish National Vascular and Endovascular Surgery Society. All rights reserved.Öğe A Sparse Approximation Based Algorithm to Detect Aortic Valve Opening from HVAD Waveforms Acquired via Monitor Snapshot(Elsevier Science Inc, 2021) Gallastegi, A. Dorken; Gallastegi, U. Dorken; Yagmur, B.; Karaca, S.; Kahraman, U.; Nalbantgil, S.; Ozbaran, M.[No Abstract Available]
