Yazar "Karaarslan, I. Kilinc" seçeneğine göre listele
Listeleniyor 1 - 12 / 12
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Blue-white variant of pigmented basal cell carcinoma(Elsevier Taiwan, 2018) Turkmen, M.; Turk, B. Gerceker; Karaarslan, I. Kilinc; Yaman, B.; Ozdemir, F.Background: Basal cell carcinoma (BCC) is the most frequent of all skin cancers in the white population. The typical dermoscopic features of pigmented BCCs have been well known. In the literature a new dermoscopic pattern of BCC has been reported as "blue-white variant". Objective: In this study, we aimed to evaluate the blue-white variant of BCC's seen in our cases at our Dermato-oncology Unit. Methods: Patient files between the years 2003-2011 were searched for the cases with the histopathologic diagnosis of BCC. Among them, the cases that were compatible with the diagnosis of blue-white variant of BCC were determined. The morphological and clinical features of the lesions, dermoscopic images together with the histopathological slides were all evaluated. Results: Among 350 histopathologically proven BCCs, 3.1% of them showed diffuse blue-white areas, namely "the blue-white variant". On histopathological examination, typical aggregates of basaloid cells with nuclear atypia connected focally to the epidermis were observed. To our knowledge, this is the first research about the blue-white variant of pigmented BCC. Conclusion: The blue-white variant of pigmented BCC seems to be the most challenging type of BCC in the diagnosis for the clinician. Copyright (C) 2018, Taiwanese Dermatological Association. Published by Elsevier Taiwan LLC.Öğe Broad-band ultraviolet B phototherapy is associated with elevated serum thiobarbituric acid reactive substance and nitrite-nitrate levels in psoriatic patients(Wiley, 2006) Karaarslan, I. Kilinc; Sagin, F. Girgin; Ertam, I.; Alper, S.; Ozturk, G.; Sozmen, E. YildirimBackground Although the local anti-inflammatory, immunosuppressive and oxidative activity of UVB is known, the systemic effect of UVB phototherapy in dermatological patients has not been investigated. Objective We aimed to investigate the lipid peroxidation status (as represented by thiobarbituric acid reactive substance, TBARS) and nitrite-nitrate levels in psoriatic patients under broad-band ultraviolet B (BB-UVB) phototherapy in order to determine the systemic effects of UVB. Subjects and methods Thirty-two psoriatic patients and 20 healthy controls were included. Blood samples were obtained at the beginning, after 6-10 exposures to BB UVB phototherapy (mean 5 weeks) and at the end of the therapy period (mean 21 weeks). Serum TBARS and nitrite-nitrate levels were evaluated. Results There was no statistically significant difference in serum TBARS and nitrite-nitrate levels between psoriatic patients (basal) and healthy volunteers. There was no statistically significant correlation between disease duration, disease severity, or the total cumulative dose of UVB and serum levels of TBARS and nitrite-nitrate in psoriatic patients. Total nitrite levels in samples obtained during and at the end of therapy were significantly higher than basal levels (P = 0.033 and P = 0.005, respectively). TBARS levels in samples obtained during and at the end of therapy were significantly higher than basal levels (P = 0 and P = 0.026, respectively). There was a negative correlation (r = -0.576, P = 0.039) between the total nitrite and TBARS levels in psoriatic patients at the end of therapy. Conclusion Our study showed that chronic exposure to UV irradiation may lead to a systemic effect on lipid peroxidation and NO levels, which are shown by a significant elevation in TBARS and nitrite-nitrate levels in serum.Öğe A case of bullous pemphigoid clinically mimicking subcorneal pustular dermatosis(Wiley, 2009) Dereli, T.; Karaca, N.; Karaarslan, I. Kilinc; Akalin, T.; Alper, S.Öğe A case of drug hypersensitivity due to azathioprine(Wiley, 2009) Karaarslan, I. Kilinc; Turkmen, M.; Ozturk, G.; Unal, I.; Ertam, I.; Kazandi, A. C.Öğe Changes in the dermoscopic appearance of melanocytic naevi after photochemotherapy or narrow-band ultraviolet B phototherapy(Wiley, 2007) Karaarslan, I. Kilinc; Teban, L.; Dawid, M.; Tanew, A.; Kittler, H.Background Although phototherapeutic modalities are commonly used for the treatment of skin diseases, the effects of therapeutic ultraviolet (UV) irradiation on the dermoscopic appearance of melanocytic naevi are unknown. Objectives We aimed to analyse the effects of photochemotherapy (psoralen plus ultraviolet A, PUVA) and narrow-band ultraviolet B phototherapy (NB-UVB) on the dermoscopic appearance of naevi. Patients and methods We monitored 187 melanocytic naevi of 38 patients receiving NB-UVB or PUVA treatment for miscellaneous skin diseases. Dermoscopic images of naevi were taken before, shortly after, and after a median of 31 weeks after the UV therapy. A random selection of naevi was covered during UV treatment, the others remained uncovered. Baseline and follow-up images of naevi were viewed side by side on a computer screen to compare size, pigmentation, and dermoscopic structure of naevi. Results Twenty-one patients received NB-UVB treatment, and 17 patients received PUVA treatment. Of 187 naevi, 70 (37%) were covered and 117 (63%) were uncovered during UV treatment. When NB-UVB- and PUVA-treated patients were analysed together, an increase in size of uncovered lesions was seen in both treatment groups. Pigmentation appeared darker at the end of UV treatment in 67.5% (n = 79) of uncovered naevi compared with 41.4% (n = 29) of covered naevi (P < 0.001). In patients receiving NB-UVB therapy, a significant increase in the number of dots or globules in 20.3% (n = 14) of uncovered naevi compared with only 5.0% (n = 2) of covered naevi (P = 0.03) was found. This effect was not observed after PUVA therapy. With the exception of four naevi with continuous enlargement and seven naevi with a persisting increase in dots and globules, the observed changes were reversible. All naevi with persistent changes belonged to the NB-UVB group. Conclusion In general, PUVA and NB-UVB therapy cause reversible dermoscopic changes in melanocytic naevi. Increase in dots and globules is more frequent with NB-UVB.Öğe Dermoscopic features in fungal melanonychia(Wiley-Blackwell, 2015) Karaarslan, I. Kilinc; Acar, A.; Aytimur, D.; Akalin, T.; Ozdemir, F.BackgroundData on the dermoscopic features of fungal melanonychia are limited. AimTo identify the dermoscopic features of fungal melanonychia. MethodsWe reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past year. ResultsIn total, 14 cases with 20 involved nails were reviewed. The most common type of melanonychia was melanonychia striata (7/20). Multicoloured pigmentation was observed in 19 of the nails. The main dermoscopic pattern was homogeneous pigmentation; however, black pigmented aggregates, presenting as either coarse granules or pigmented clumps, accompanied this homogeneous pigmentation in 16 lesions. Matt black pigmentation, matt white pigmentation, yellow to brown pigmentation, black reverse triangle (wider at the distal than the proximal end), superficial transverse striation and blurred appearance were the other features. ConclusionsWe have identified a number of dermoscopic features appearing in fungal melanonychia, which should help in diagnosis of this disease.Öğe Dermoscopic features in fungal melanonychia(Wiley-Blackwell, 2015) Karaarslan, I. Kilinc; Acar, A.; Aytimur, D.; Akalin, T.; Ozdemir, F.BackgroundData on the dermoscopic features of fungal melanonychia are limited. AimTo identify the dermoscopic features of fungal melanonychia. MethodsWe reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past year. ResultsIn total, 14 cases with 20 involved nails were reviewed. The most common type of melanonychia was melanonychia striata (7/20). Multicoloured pigmentation was observed in 19 of the nails. The main dermoscopic pattern was homogeneous pigmentation; however, black pigmented aggregates, presenting as either coarse granules or pigmented clumps, accompanied this homogeneous pigmentation in 16 lesions. Matt black pigmentation, matt white pigmentation, yellow to brown pigmentation, black reverse triangle (wider at the distal than the proximal end), superficial transverse striation and blurred appearance were the other features. ConclusionsWe have identified a number of dermoscopic features appearing in fungal melanonychia, which should help in diagnosis of this disease.Öğe Dermoscopic features in fungal melanonychia(Wiley-Blackwell, 2015) Karaarslan, I. Kilinc; Acar, A.; Aytimur, D.; Akalin, T.; Ozdemir, F.BackgroundData on the dermoscopic features of fungal melanonychia are limited. AimTo identify the dermoscopic features of fungal melanonychia. MethodsWe reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past year. ResultsIn total, 14 cases with 20 involved nails were reviewed. The most common type of melanonychia was melanonychia striata (7/20). Multicoloured pigmentation was observed in 19 of the nails. The main dermoscopic pattern was homogeneous pigmentation; however, black pigmented aggregates, presenting as either coarse granules or pigmented clumps, accompanied this homogeneous pigmentation in 16 lesions. Matt black pigmentation, matt white pigmentation, yellow to brown pigmentation, black reverse triangle (wider at the distal than the proximal end), superficial transverse striation and blurred appearance were the other features. ConclusionsWe have identified a number of dermoscopic features appearing in fungal melanonychia, which should help in diagnosis of this disease.Öğe Eruptive disseminated Spitz naevi: dermatoscopic features(Wiley, 2009) Karaarslan, I. Kilinc; Ozdemir, F.; Akalin, T.; Ozturk, G.; Turk, B. G.; Kandiloglu, G.Eruptive disseminated Spitz naevi is a rarely reported condition. Although the dermatoscopic features of nondisseminated, solitary forms of Spitz naevi are well known, there are no reports describing the dermatoscopic features of eruptive disseminated variant. We report an additional case and describe the dermatoscopic features. Two patterns were observed. In all pink lesions, the vascular pattern was seen, composed of dotted, linear or comma-like vessels located at the centre of the meshes of the reticular depigmentation. In all brown lesions, we observed only the reticular pattern, which is quite interesting as the reticular pattern is a rare feature of Spitz naevi. This observation may be a special feature particularly seen in the eruptive disseminated variant. A superficial black network also accompanied reticular pattern in some lesions. In dichromatic lesions, both patterns were observed in different areas of the body.Öğe Eruptive disseminated Spitz naevi: dermatoscopic features(Wiley, 2009) Karaarslan, I. Kilinc; Ozdemir, F.; Akalin, T.; Ozturk, G.; Turk, B. G.; Kandiloglu, G.Eruptive disseminated Spitz naevi is a rarely reported condition. Although the dermatoscopic features of nondisseminated, solitary forms of Spitz naevi are well known, there are no reports describing the dermatoscopic features of eruptive disseminated variant. We report an additional case and describe the dermatoscopic features. Two patterns were observed. In all pink lesions, the vascular pattern was seen, composed of dotted, linear or comma-like vessels located at the centre of the meshes of the reticular depigmentation. In all brown lesions, we observed only the reticular pattern, which is quite interesting as the reticular pattern is a rare feature of Spitz naevi. This observation may be a special feature particularly seen in the eruptive disseminated variant. A superficial black network also accompanied reticular pattern in some lesions. In dichromatic lesions, both patterns were observed in different areas of the body.Öğe Folliculotropic T-cell lymphocytosis as an associated finding in mycosis fungoides(Wiley, 2009) Karaarslan, I. Kilinc; Turkmen, M.; Ertekin, B.; Akalin, T.; Ozturk, G.Öğe Unilateral generalized morphoea: could vibration be a stimulating factor?(Wiley-Blackwell, 2010) Turk, B. Gerceker; Urkmez, A.; Karaarslan, I. Kilinc; Ertam, I.; Kandiloglu, G.; Dereli, T.
