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Öğe Anaplastic astroblastoma of childhood: aggressive behavior(Springer, 2009) Kantar, M.; Ertan, Y.; Turhan, T.; Kitis, O.; Anacak, Y.; Akalin, T.; Ersahin, Y.; Cetingul, N.Objective Astroblastoma is an unusual brain tumor in childhood. Tumor usually arises from cerebral hemispheres. This large tumor is well-demarcated, lobulated, solid or cystic, and therefore, may resemble glioblastoma. Histopathologically, there are two types of astroblastoma: well-differentiated (low-grade) or anaplastic (high-grade). In low-grade astroblastoma, treatment of choice is complete excision. This type of tumor usually does not recur. However, anaplastic tumors can recur despite surgery, radiation, and chemotherapy and may be problematic for clinician. Case Report A 7-year-old female patient presented with an acute onset of vomiting and seizure. Magnetic resonance imaging study revealed a large mass in the left parietooccipital region. She underwent total excision of the tumor. Histopathologically, the tumor was an anaplastic astroblastoma. Her adjuvant treatment was planned to consist of radiation therapy and cisplatin-based chemotherapy. However, the tumor recurred early in the course, and she died 18 months after diagnosis. Conclusion High-grade astroblastomas behave like glioblastoma, as emphasized in this case report. Local control of this type of tumor seems difficult despite surgery, radiation therapy, and cisplatin-based chemotherapy.Öğe Anaplastic astroblastoma of childhood: aggressive behavior(Springer, 2009) Kantar, M.; Ertan, Y.; Turhan, T.; Kitis, O.; Anacak, Y.; Akalin, T.; Ersahin, Y.; Cetingul, N.Objective Astroblastoma is an unusual brain tumor in childhood. Tumor usually arises from cerebral hemispheres. This large tumor is well-demarcated, lobulated, solid or cystic, and therefore, may resemble glioblastoma. Histopathologically, there are two types of astroblastoma: well-differentiated (low-grade) or anaplastic (high-grade). In low-grade astroblastoma, treatment of choice is complete excision. This type of tumor usually does not recur. However, anaplastic tumors can recur despite surgery, radiation, and chemotherapy and may be problematic for clinician. Case Report A 7-year-old female patient presented with an acute onset of vomiting and seizure. Magnetic resonance imaging study revealed a large mass in the left parietooccipital region. She underwent total excision of the tumor. Histopathologically, the tumor was an anaplastic astroblastoma. Her adjuvant treatment was planned to consist of radiation therapy and cisplatin-based chemotherapy. However, the tumor recurred early in the course, and she died 18 months after diagnosis. Conclusion High-grade astroblastomas behave like glioblastoma, as emphasized in this case report. Local control of this type of tumor seems difficult despite surgery, radiation therapy, and cisplatin-based chemotherapy.Öğe Anaplastic Ependymoma: Experience of Three Centers in Western Part of Turkey(Wiley, 2019) Ataseven, E.; Onen, S.; Kizmazoglu, D.; Demirag, B.; Bolat, E.; Kamer, S.; Kantar, M.[No abstract available]Öğe CAN TEMOZOLOMIDE EXTEND SURVIVAL OF DIFFUSE INTRINSIC BRAINSTEM GLIOMAS?(Elsevier Ireland Ltd, 2010) Kamer, S.; Mutluer, S.; Anacak, Y.; Kantar, M.; Cetingul, N.; Ersahin, Y.Öğe Dysembryoplastic Neuroepithelial Tumour of Childhood: EGE University Experience(Wiley-Blackwell, 2016) Sahin, A.; Kantar, M.; Turhan, T.; Akalin, T.; Kitis, O.; Bolat, E.; Eraslan, C.; Ertan, Y.; Serdaroglu, G.; Cetingul, N.; Anacak, Y.; Mutluer, S.Öğe The Effect of Radiation Therapy in the Local Control of the Non-extremity Ewing Sarcomas(Elsevier Science Inc, 2014) Akagunduz, O. Ozkaya; Kamer, S. Arun; Kececi, B.; Kadioglu, B.; Oniz, H.; Kantar, M.; Cetingul, N.; Sabah, D.; Anacak, Y.Öğe The Effect of Vitamin D Levels and Fok 1 VDR Gene Polymorphism on Long Term Bone Health in Pediatric Cancer Survivors(Wiley, 2017) Cetingul, N.; Sivis, Z. Onder; Ozen, S.; Onay, H.; Goksen, D.; Burak, Z.; Oral, A.; Kantar, M.; Aksoylar, S.; Özkınay, FerdaÖğe Fertility-Related Views and Life Priorities of Children Having Undergone Cancer Treatment and their Parents(Wiley, 2018) Yilmaz, M.; Demir, N.; Sari, H. Yildirim; Cetingul, N.; Tavmergen, L.; Kantar, M.Öğe Granulocytic Sarcomas in Children Can Present Like Solid Tumors; Experience of EGE University from Turkey(Wiley-Blackwell, 2016) Ozdemir, H. Hekimci; Cetingul, N.; Akinci, B.; Ozdemir, O.; Kantar, M.; Aksoylar, S.; Hekimgil, M.; Ozsan, N.; Kamer, S.; Anacak, Y.; Kansoy, S.Öğe HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LANGERHANS CELL HISTIOCYTOSIS(Ferrata Storti Foundation, 2014) Karadas, N.; Aksoylar, S.; Kansoy, S.; Kantar, M.; Cetingul, N.; Sivis, Z. O.; Akinci, A. B.Öğe HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LANGERHANS CELL HISTIOCYTOSIS (EXPERIENCE OF EGE UNIVERSITY FROM TURKEY)(Wiley-Blackwell, 2014) Cetingul, N.; Aksoylar, S.; Kansoy, S.; Kantar, M.; Demirag, B.; Akinci, B.Öğe Hematopoietic Stem Cell Transplantation In Pediatric Langerhans Cell Histiocytosis: Experience of Ege University From Turkey(Nature Publishing Group, 2015) Gozmen, S.; Aksoylar, S.; Cetingul, N.; Kantar, M.; Sivis, Z. Onder; Kansoy, S.Öğe Hematopoietic Stem Cell Transplantation In Pediatric Langerhans Cell Histiocytosis: Experience of Ege University From Turkey(Nature Publishing Group, 2015) Gozmen, S.; Aksoylar, S.; Cetingul, N.; Kantar, M.; Sivis, Z. Onder; Kansoy, S.Öğe Hematopoietic Stem Cell Transplantation In Pediatric Langerhans Cell Histiocytosis: Experience of Ege University From Turkey(Nature Publishing Group, 2015) Gozmen, S.; Aksoylar, S.; Cetingul, N.; Kantar, M.; Sivis, Z. Onder; Kansoy, S.Öğe High Dose Rate (HDR) Brachytherapy in Childhood Rhabdomyosarcomas: Experience of a Single Center(Wiley, 2017) Kamer, S.; Celik, A.; Avanoglu, A.; Ergun, O.; Palamar, M.; Yagci, A.; Kadioglu, B.; Cetingul, N.; Kantar, M.; Turhan, T.; Anacak, Y.Öğe Intestinal protozoan parasitic infections in immunocompromised child patients with diarrhea(National Institute of Health, 2020) Caner, A.; Zorbozan, O.; Tunalı, V.; Kantar, M.; Aydoğdu, S.; Aksoylar, S.; Turgay, N.Intestinal protozoan parasites are common causes of infectious diarrhea in children receiving anticancer therapy or undergoing transplantation. Additionally, immunosuppression therapy in such patients may exacerbate the symptoms related to these parasitic infections. The aim of this study was to evaluate the prevalence and diagnostic importance of parasitic protozoan infections in children treated for malignancies or undergoing transplantation, and to highlight the control of intestinal parasitic infections for immunosuppressed patients at a hospital in İzmir, Turkey. In total, 82 stool samples from 62 patients were analyzed by microscopic examination and polymerase chain reaction (PCR) for the presence of coccidian parasites. Our results showed that Cryptosporidium, Cyclospora, and Cystoisospora were present in 22.5% (14/62), 9.6% (6/62), and 3.2% (2/62) of the cases using either method, respectively. The prevalence of these coccidian parasites identified with both methods was 35.4% (20/62). Other intestinal parasites (Blastocystis, Giardia, and Entamoeba coli) were detected in 10 patients. PCR analysis showed the presence of all coccidian parasites in the same stool sample for one patient. Finally, both PCR and microscopic examination of the stools revealed that there is a higher prevalence of Cryptosporidium, Cyclospora, and Cystoisospora in immunocompromised children. These examinations allowed an early start of appropriate antibiotic treatments and led to an increased percentage of correctly treated patients. © 2020, National Institute of Health. All rights reserved.Öğe Investigation of Molecular Sub-Groups by Immunohistochemical Methods and its Prognostic Importance in Medulloblastoma(Wiley, 2021) Ataseven, E.; Kantar, M.; Aktas, S.; Erol, A.; Gokbayrak, O.; Ertan, Y.; Kamer, S.[No Abstract Available]Öğe Investigation of Quality of Life and Healthy Life Style Behaviors of Adolescents Having Undergone Cancer Treatment(Wiley, 2018) Demir, N.; Yilmaz, M.; Acikel, E.; Kantar, M.; Cetingul, N.Öğe A late-onset Epstein-Barr virus-related lymphoma completely remitted in a child with renal allograft(Elsevier Science Inc, 2007) Mutlubas, F.; Mir, S.; Ozkayin, N.; Ozbek, S. S.; Kantar, M.; Sen, S.Lymphomas are frequently encountered malignancies following renal transplantations. A 17-year-old boy was found to have lymphoma 1.5 years after a the first cadaveric transplantation performed due to reflux nephropathy. Polyclonal anti-thymocyte globulin (induction) with prednisolone (PRD), azathioprine (AZT), and tacrolimus (Tac) regimen had been given after the transplantation. A hypoechoic mass (25 mm) was detected in the upper pole of the allograft by renal Doppler ultrasound performed due to graft dysfunction with a high basal serum creatinine (Cr) (2.2 mg/dL). The renal biopsy revealed a large B-cell lymphoma with CD20 staining in the medulla. The serum displayed a positive Epstein-Barr virus (EBV), immunoglobulin (Ig)G, negative IgM with negative DNA-polymerase chain reaction. However, the biopsy was positive for EBV-LMA. The viral status at the time of transplant was unknown. After withdrawing AZT and Tac therapies, a chemoimmunotherapeutic regimen consisting of PRD, cyclophosphamide, and anti-CD20 monoclonal antibody was administered twice. The patient excreted the necrosed tumor particles over a 2-month interval with hydronephrotic colic attacks. The basal Cr improved at 6 months (to 1.4 mg/dL). A low dose of Tac (0.5 mg/d) was added to PRD. The patient has remained in complete remission for 2.5 years with a well-functioning renal allograft. Although this case was a late-onset lymphoma, the patient displayed a picture like excreting stones from the allograft and remitted completely. This case illustrates that localization of a tumor may play a more important role than the elapsed time from transplant in the diagnosis in EBV-related posttransplant lymphoproliferative disease.Öğe MIFAMURTIDE (L-MTP-PE) IN CHILDREN WITH OSTEOSARCOMA: THE TURKISH EXPERIENCE(Wiley-Blackwell, 2014) Kebudi, R.; Ilhan, I.; Kantar, M.; Cakir, F. B.; Guler, E.; Olgun, N.; Celkan, T.
