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    Epidemiology of Pemphigus in Turkey: One-year Prospective Study of 220 Cases
    (Croation Dermatovenerological Soc, 2017) Yayli, Savas; Harman, Mehmet; Baskan, Emel Bulbul; Karakas, Ayse Akman; Genc, Yeser; Turk, Bengu Gerceker; Demirsoy, Evren Odyakmaz; Gunasti, Suhan; Bilgili, Serap Gunes; Ilter, Nilsel; Ferahbas, Ayten; Savk, Ekin; Afsar, Fatma Sule; Aytekin, Sema; Kaya, Tamer Irfan; Hayta, Sibel Berksoy; Ozgen, Zuleyha; Gurel, Mehmet Salih; Caliskan, Ercan; Balci, Didem Didar; Gungor, Sule; Kapicioglu, Yelda; Ozuguz, Pinar; Aktan, Sebnem; Dogramaci, Asena; Kokcam, Ibrahim; Onsun, Nahide; Seckin, Deniz; Durdu, Murat; Dursun, Recep; Daye, Munise; Dilek, Nursel; Karabacak, Ercan; Temel, Asli Bilgic; Erdem, Cengizhan; Altun, Ece; Gungor, Dilek; Kartal, Demet; Akyol, Melih; Aksu, Esra Koku; Uzun, Soner
    Pemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. All patients newly diagnosed with pemphigus between June 2013 and June 2014 were prospectively enrolled in 33 dermatology departments in 20 different provinces from all seven regions of Turkey. Disease parameters including demography and clinical findings were recorded. A total of 220 patients were diagnosed with pemphigus during the 1-year period, with an annual incidence of 4.7 per million people in Turkey. Patients were predominantly women, with a male to female ratio of 1:1.41. The mean age at onset was 48.9 years. Pemphigus vulgaris (PV) was the commonest clinical subtype (n= 192; 87.3%), followed by pemphigus foliaceus (n= 21; 9.6%). The most common clinical subtype of PV was the mucocutaneous type (n= 83; 43.2%). The mean Pemphigus Disease Area Index was 28.14 +/- 22.21 (mean +/- Standard Deviation). The incidence rate of pemphigus in Turkey is similar to the countries of South-East Europe, higher than those reported for the Central and Northern European countries and lower than the countries around the Mediterranean Sea and Iran. Pemphigus is more frequent in middle-aged people and is more common in women. The most frequent subtype was PV, with a 9-fold higher incidence than pemphigus foliaceus.
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    In vivo reflectance confocal microscopy terminology in the Turkish language
    (Deri Zuhrevi Hastaliklar Dernegi, 2021) ozdemir, Fezal; Gurel, Mehmet Salih; Karaarslan, Isil; Erdemir, Vefa Asli Turgut; Aksu, Ayse Esra Koku; Acar, Ayda
    In vivo reflectance confocal microscopy (RCM) is a diagnostic method to examine a skin lesion at the cellular level in vivo without biopsy. It provides non-invasive, high resolution imaging for diagnosis and follow-up of malignant, benign skin tumors and inflammatory dermatologic diseases, and its use is spreading worldwide. Standard terminology which has been used in RCM was described earlier in the English language. This study aimed to propose a Turkish terminology for RCM to allow Turkish-speaking dermatologists to communicate in a homogeneous language and familiarize themselves with the terminology of this new diagnostic technic. Six Turkish-speaking dermatologists with RCM experience participated in the study. RCM terminology used in English was determined and translated into Turkish. Turkish terms and their definitions were reviewed by each participant and the consensus was provided in the group. Finally, philology department examined the last version of the terms and the study was finalized. The terms, definitions and the translations of the terms have been identified, and the Turkish RCM terminology has been created and shown. Turkish RCM terminology will provide Turkish-speaking dermatologists to describe their findings in a homogenous language.