Yazar "Gumuser, Gul" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Effects of aerobic plus explosive power exercises on bone remodeling and bone mineral density in young men
    (Walter De Gruyter Gmbh, 2018) Cay, Veysi; Buyukyazi, Gurbuz; Ulman, Cevval; Taneli, Fatma; Dogru, Yeliz; Tikiz, Hakan; Gumuser, Gul; Oran, Arzu; Keskinoglu, Pembe
    Objectives: This study aims to examine effects of aerobic jogging and explosive power exercises on body composition, maximal oxygen consumption (MaxVO(2)), bone mineral density (BMD) and bone turn-over markers: serum bone alkaline phosphatase (BAP), C terminal telopeptide (CTx), Procollagen type I N-terminal propeptide (PINP), in men aged between 20 and 40. Materials and methods: Thirty seven healthy males were divided into exercise group (EG, n = 19) and control group (CG, n = 18). EG completed 10 weeks of outdoor aerobic (jogging at 60-70% maximal heart rate reserve starting from 20 min steadily increasing up to 28 min) and explosive power exercises (in 2-3 sets, with maximum repetitions lasting 15 s), 3 times per week. All measurements were taken before and after the exercise program. BMD was measured via dual energy X-ray absorptiometry (DEXA). Results: Body mass index (p < 0.001) significantly decreased; MaxVO(2) (p < 0.001), femur neck (p = 0.036) and total score BMD significantly increased in EG (p = 0.034). BAP and vitamin D increased in both groups (p < 0.001). Conclusion: Performing our outdoor exercise program in spring months might have an important role in the significant increase (9 vs. 22 ng/mL) in mean vitamin D level, which reached above the fracture risk level of 20 ng/mL.
  • Küçük Resim Yok
    Öğe
    Multifunctional molecular imaging probes for estrogen receptors: Tc-99m labeled diethylstilbestrol (DES) conjugated, cuinp quantum dot nanoparticles (DESCIP)
    (Springer, 2017) Moharrami, Payam; Unak, Perihan; Guldu, Ozge Kozgus; Medine, E. I.; Gumuser, Gul; Bilgin, Elvan Sayit; Aras, Omer
    A theranostic nanoparticle was synthesized based on diethylstilbestrol conjugated with phosphate, copper, and indium (DESCIP) and labelled with Tc-99m which can be used for SPECT imaging of ER-enriched cancers. In vitro biological activity of Tc-99m-DESCIP was examined in breast adenocarcinoma cells (MCF-7), prostatic carcinoma cells (PC-3), and pulmonary epithelial cells (A-549). In vivo lymph node imaging was performed in normal and receptor blocked female New Zealand rabbits. Results demonstrated that Tc-99m-DESCIP and DESCIP has potential for imaging ER-enriched tumors such as breast and prostate tumors, and their metastases in the lung, as well as improving management for their therapies.