Yazar "Günaydin A." seçeneğine göre listele

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    Complications of laser [Lazer komplikasyonlari]
    (2012) Günaydin A.; Dereli T.
    Lasers are the therapeutic modalities becoming more commonly used and the incidence of complications increases in direct proportion to diversity. Pain, erythema, edema, blister formation, infection, pigmentation disorder and scarring are some of these complications. However, with an appropriate patient and laser selection, detailed patient history and close patent monitoring rate of complications can be minimized. In this review, laser complications examined by indication groups and emphasized about the measures to minimize morbidity rate.
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    Erythema multiforme like lesions in a case of systemic lupus erythematosus [Sistemik lupus eritematozuslu bir olguda eritema multiforme benzeri deri lezyonlari{dotless}]
    (2012) Günaydin A.; Karaarslan I.K.; Ertam I.; Karadadaş H.; Türk B.G.; Kandiloglu G.; Ünal I.
    Cutaneous involvement may be seen in 70-85% of patients with systemic lupus erythematosus. Erythema multiforme like lesions are considered as non-specific findings in lupus erythematosus and are rarely seen in the systemic form. Seventeen-year-old woman admitted to our clinic with multiple, violet colored, targetoid lesions on the palms and dorsal areas of both hands and dorsal areas of the feet with a 4-month of duration. She was complaining of photosensitivity and hair loss for a few years. Histopathologic examination revealed hyperkeratosis, parakeratosis, single cell necrosis through the epidermis and perivascular mixed cellular infiltration. C3 and C1q were detected at the dermoepidermal junction in immunofluorescence examination. In laboratory, antinuclear antibody was positive. Elevated sedimentation rate, anemia, and hypocomplementemia were detected. Lupus band test was positive. According to these findings, the patient was diagnosed as systemic lupus erythematosus and the lesions on the hand and feet as erythema multiforme like lesions. Methylprednisolone (1mg/kg/day) was started. Notable improvement in her symptoms and in the clinical appearance of the lesion was observed. Erythema multiforme like lesions are the cutaneous findings rarely seen in systemic lupus erythematosus. In the present case, since there was no drug use or herpes virus infection in the history.
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    Mucocutaneous findings in pediatric patients with bone marrow transplantation [Kemik iligi transplantasyonu yapilan pediyatrik olgularda mukokutanöz bulgular]
    (Istanbul Assoc. of Dermatology and Venerology, 2017) Aksoylar S.; Ceylan C.; Günaydin A.; Ertam I.; Kantar M.; Tuna A.; Çetingül N.; Kansoy S.
    Background and Design: Bone marrow transplantation (BMT) is performed for many malign and non-malign diseases in pediatric patients. Cutaneous signs in transplant patients are usually encountered in the presence of underlying primary diseases or due to the intense conditioning regimens that include chemotherapy and radiotherapy protocols. In this study, it is aimed to define mucocutaneous changes in pediatric patients with BMT. Materials and Methods: A total of 44 patients, in whom BMT was planned between 2010 and 2011, were included in the study. Dermatological examinations were performed at the beginning of the study and were repeated once a week in the first month, once a month in the following 5 months; and once in every 3 months in the last 1.5 years of follow-up. Results: Forty-one patients were completed the study. The mean age of 41 patients was 9.24 years (range: 1-17 years). Of the subjects, 26 (64%) were male and 15 (36%) were female. Dermatological signs, in order of frequency, were mucositis (75.6%), xeroderma (70.7%), alopecia (46.3%), nail disorders (24.3%), inflammatory skin diseases (24.2%), aphthous stomatitis (22%), cutaneous hyperpigmentation (22%), graft versus host diseases (17.1%), infectious diseases (15.5%), and maculopapular rash (4.8%). Conclusion: Dermatological diseases can be frequently observed in BMT patients. Close monitoring of dermatological signs is important to minimize the complications of the treatment in this patient group. © Telif Hakki 2017 Deri ve Zührevi Hastaliklar Dernegi.
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    Psoriasis and metabolic syndrome [Psoriasis ve metabolik sendrom]
    (Istanbul Assoc. of Dermatology and Venerology, 2014) Günaydin A.; Aytimur D.; Özdemir F.
    Background and Design: Psoriasis is a chronic, inflammatory disease that occurs with polygenic and other triggering factors. The association of psoriasis, which is considered to be a systemic disease, with other diseases, such as cardiovascular diseases, hepatosteatosis, obesity, diabetes mellitus, hypertension, and hyperlipidemia has been shown. Materials and Methods: In this study, we compared the levels of fasting blood glucose, serum lipid (total cholesterol, HDL cholesterol, triglyceride), basal insulin, insulin resistance and body mass index as well as cigarette and alcohol consumption in 50 adult patients with those in 50 age- and gender-matched non-psoriatic controls. Results: In our study, metabolic syndrome was present in 62% patients with psoriasis, compared with 24% of the controls (p<0,001). In psoriatic patients with metabolic syndrome PASI median value was 13,6, whereas patients without metabolic syndrome PASI median value was 11,2 and the difference was statistically significant (p<0,001). Conclusion: In our study, the frequency of metabolic syndrome and its components diabetes mellitus, obesity, hypertension, and dyslipidemia were found to be higher in patients with psoriasis compared to that in non-psoriatic controls.
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    Tinea corporis: Five-year retrospective evaluation [Tinea korporis: Beş yillik retrospektif degerlendirme]
    (Istanbul Assoc. of Dermatology and Venerology, 2014) Günaydin A.; Aytimur D.
    Background and Design: Tinea corporis, a cutaneous infection of the glabrous skin, excluding palms-soles, nails and groins, is caused by dermatophytes.The distribution of agents varies depending on geographical and socio-economic factors. In this study, we aimed to analyze the agents seen in tinea corporis and their relationship with patient age, gender and lesion location. Materials and Methods: In this study, we retrospectively analyzed mycological examination results of 62 patients (62.9% female, 37.1% male) who attended our dermatology outpatient clinic and were diagnosed with tinea corporis between January 2007 and December 2011. The results were compared in terms of patient age, sex and location of lesions for the statistical significance. Results: The average age of the patients was 40.5 years. Trichophyton rubrum was the most prevalent etiologic organism in both gender (56.5%), followed by Microsporum canis (35.5%), Trichophyton violaceum (4.8%) and Trichophyton mentagrophytes (3.2%). The prevalence of Microsporum canis was 46.5% in women and 17.3% in men; the difference was attributed to the fact that women have more close contact with pets, which are an important source of contamination for The zoophilic dermatophyte Microsporum canis, than do men. Conclusion: In our study, the frequency and the species of tinea corporis were found to be similar to that in the literature. There was no statistically significant difference between the variables of agent species, localization, gender and age. However, epidemiological data can be important in the management of the disease in conditions that mycological culture cannot be considered.
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    Vulvar cicatricial pemphigoid of childhood: A case report [Vulvar sikatrisyel pemfigoid: Bir çocuk olgu]
    (Istanbul Assoc. of Dermatology and Venerology, 2014) Günaydin A.; Türk B.G.; Kandiloglu G.; Dereli T.
    Vulvar cicatricial pemphigoid is a rare variant of bullous pemphigoid, which is characterized by isolated and localized vulvar involvement, observed in childhood. The typical clinical finding is erosive lesions of the vulva healing with scar formation. Ocular involvement may be associated with vulvar disease or may develop during the follow-up. On histopathologic examination of the lesions, subepidermal blister and on direct immunofluorescence study, linear deposition of Ig G and C3 are observed. The differential diagnosis includes lichen sclerosus and, sexual abuse should be considered at first. Topical and systemic steroids and dapsone are the main treatment options. Ophthalmological examination and follow-up should be repeated on every six months for ocular involvement. Here, we report development of vulvar cicatricial pemphigoid in an 11-year-old girl with clinical and histopathological findings.