Yazar "Gökalp, Cenk" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Life-Threatening Hypokalemia Presenting with Paralysis after Percutaneous Nephrolithotomy in a Patient with Nephrolithiasis: A Case Report(2020) Gökalp, Cenk; Duman, Soner; Otman, Eda; Doğan, Fulya; Güner, Merve; Bahçeci, TuncerDistal renal tubular acidosis (Type 1 RTA) is an acid-base disorder characterized by impaired urinary acidification by the distal tubule. Osteomalacia, rickets, nephrocalcinosis, nephrolithiasis, and electrolyte imbalance can be seen in these cases. We report the case of a 24-year-old male patient who had low back pain with a history of nephrolithiasis. Routine laboratory results revealed mild hypokalemia and hyperchloremia. After percutaneous nephrolithotomy surgery, he developed muscle paralysis with a serum potassium level of 1.3 mEq/L. After intensive treatment of hypokalemia, the patient had normal anion gap metabolic acidosis, high urine pH, high transtubular potassium gradient, nephrocalcinosis, and hypercalciuria and was thus diagnosed as having distal RTA. After stabilization of the patient, he was discharged with oral potassium, bicarbonate, and spironolactone medications. Hypokalemia and hyperchloremia in a patient with a history of recurrent renal stones should be kept in mind for a possible distal RTA diagnosis. Prompt diagnosis and treatment of this situation not only reduces the formation of renal stones, but also may be lifesaving in rare cases.Öğe New Method to Predict Survival in Hemodialysis Patients Using the Impedance Ratio(2019) Hür, Ender; Gökalp, Cenk; Köse, Şennur; Duman, Elif; Mağden, Kemal; Yıldız, Gürsel; Duman, SonerObjective: Bioimpedance spectroscopy (BIS) can be used to determine hypervolemia and malnutrition in chronic hemodialysis (HD) patients. In this prospective observational study, we investigated the survival predictability of impedance ratio (IR) calculated by BIS in HD patients (Clinical Trials Gov Identifier: NCT01468363). Materials and Methods: A total of 430 chronic HD patients, out of 500 prevalent chronic HD patients from the city of Zonguldak who met the inclusion criteria, were included in the study. With a mean follow-up of 32.2±14.4 months, BIS was performed in all patients. The IR percentage (IR%) was calculated by dividing the resistance values using the 200 kHz and 5 kHz impulses. Student’s t-test, Cox regression analysis, and Kaplan–Meier survival analysis were performed, and a p<0.05 was accepted as statistically significant. Results: The mean age of 430 patients was 59±15 (10-92) years, and 54% of patients were male. By the end of the study, 125 (29%) patients died. Diabetes mellitus was observed in 46% of patients. Sixty-seven percent of patients used erythropoietin, and 41% used diuretics. The mean systolic blood pressure of patients before the dyalisis was 133±26 mmHg, and diastolic blood pressure was 79±12 mmHg. The IR values ranged between 73.2% and 94.1%. A multi-regression analysis that used the IR and included diabetes mellitus, age, gender, and albumin and hemoglobin levels showed that the mortality risk increased 16% (p<0.001). Evaluation using the quartiles showed decreased survival. Survival in the first quartile group was 42.8 months compared to 30.6 months in the last quartile group. Conclusion: The IR calculated using BIS data is a useful tool that can be employed to predict the survival in chronic HD patients. An early awareness of this increased mortality risk is important in terms of a close follow-up and appropriate treatment of these patients.Öğe New Method to Predict Survival in Hemodialysis Patients Using the Impedance Ratio(2019) Hür, Ender; Gökalp, Cenk; Köse, Şennur; Duman, Elif; Mağden, Kemal; Yıldız, Gürsel; Sezer, SirenObjective: Bioimpedance spectroscopy (BIS) can be used to determine hypervolemia and malnutrition in chronic hemodialysis (HD) patients. in this prospective observational study, we investigated the survival predictability of impedance ratio (IR) calculated by BIS in HD patients (Clinical Trials Gov Identifier: NCT01468363). Materials and Methods: A total of 430 chronic HD patients, out of 500 prevalent chronic HD patients from the city of Zonguldak who met the inclusion criteria, were included in the study. With a mean follow-up of 32.2±14.4 months, BIS was performed in all patients. the IR percentage (IR%) was calculated by dividing the resistance values using the 200 kHz and 5 kHz impulses. Student’s t-test, Cox regression analysis, and Kaplan–Meier survival analysis were performed, and a p<0.05 was accepted as statistically significant. Results: the mean age of 430 patients was 59±15 (10-92) years, and 54% of patients were male. By the end of the study, 125 (29%) patients died. Diabetes mellitus was observed in 46% of patients. Sixty-seven percent of patients used erythropoietin, and 41% used diuretics. the mean systolic blood pressure of patients before the dyalisis was 133±26 mmHg, and diastolic blood pressure was 79±12 mmHg. the IR values ranged between 73.2% and 94.1%. A multi-regression analysis that used the IR and included diabetes mellitus, age, gender, and albumin and hemoglobin levels showed that the mortality risk increased 16% (p<0.001). Evaluation using the quartiles showed decreased survival. Survival in the first quartile group was 42.8 months compared to 30.6 months in the last quartile group. Conclusion: the IR calculated using BIS data is a useful tool that can be employed to predict the survival in chronic HD patients. An early awareness of this increased mortality risk is important in terms of a close follow-up and appropriate treatment of these patients.Öğe Prostat kanseri hücre hatlarında zoledronik asit uygulamasının sitotoksik ve anti-anjiogenik etkilerinin araştırılması(Ege Üniversitesi, 2011) Gökalp, Cenk; Uslu, F. Rüçhan