Yazar "Erdogan T.F." seçeneğine göre listele

Listeleniyor 1 - 5 / 5
  • Küçük Resim Yok
    Öğe
    Antimicrobial and cytotoxic activities of Tripleurospermum parviflorum (Willd.) Pobed [Tripleurospermum parviflorum (Willd.) Pobed.'in antimikrobiyal ve sitotoksik aktiviteleri]
    (2013) Erdogan T.F.; Gönenç T.M.; Oskay M.
    The antimicrobial and cytotoxic activities of n-hexane, methanol, ethanol, ethyl acetate and water extracts of Tripleurospermum parviflorum (Willd.) Pobed. were evaluated in this study. The antimicrobial activities of the extracts were reported against Escherichia coli ATCC 29998, Escherichia coli ATCC 25922, Escherichia coli ATCC 11230, Staphylococcus aureus ATCC 6538P, Staphylococcus aureus ATCC 29213, Enterobacter cloacae ATCC 13047, Enterococcus faecalis ATCC 29212, Pseudomonas aeroginosa ATCC 27853 as bacteria and Candida albicans ATCC 10239 as yeastlike fungi by disc diffusion method. Cytotoxic activity of the extracts was tested in vitro against Brine shrimp. All of the extracts showed a range of activity against the tested bacteria and brine shrimp.
  • Küçük Resim Yok
    Öğe
    Brine shrimp lethality bioassay of Fumaria densiflora Dc. and Fumaria officinalis L. extracts
    (2008) Erdogan T.F.
    The cytotoxic activities of Herba Fumariae officinalis and Herba Fumariae densiflorae prepared from Fumaria officinalis L., growing wildly in Bagsaray (Burdur) and Fumaria densiflora DC., growing wildly in Kemalpaşa town Ulucak village (İzmir), respectively were determined. LC50 value of n-hexane, ethyl acetate, ethanol, methanol and water extracts of the plant materials were determined using brine shrimp (Artemia salina) lethality bioassay. The n-hexane and ethyl acetate extracts of Fumaria densiflora DC. and the n-hexane extract of F. officinalis L. showed cytotoxic activity against the brine shrimp.
  • Küçük Resim Yok
    Öğe
    Brine shrimp lethality bioassay of some Verbascum species growing in Turkey
    (2008) Tatli I.I.; Erdogan T.F.; Kahraman C.; Kivcak B.; Akdemir Z.S.
    Verbascum L. (Scrophulariaceae) species are medicinal plants that have been used for the treatment of inflammatory diseases, asthma, spasmodic coughs and other pulmonary problems in Anatolia and in several countries. The objective of this study was to assess the in vivo cytotoxic activities of thirteen Verbascum extracts including V. chionophyllum Hub.-Mor., V. cilicicum Boiss., V. dudleyanum (Hub.-Mor.) Hub.-Mor., V. lasianthum Boiss., V. latisepalum Hub.-Mor., V. mucronatum Lam., V. olympicum Boiss., V. pterocalycinum var. mutense Hub.-Mor., V. pycnostachyum Boiss. & Heldr., V. salviifolium Boiss., V. splendidum Boiss., V. stachydifolium Boiss. & Heldr and V. uschackense (Murb.) Hub.-Mor. using brine shrimp (Artemia salina) lethality bioassay. The methanolic extracts of V. chionophyllum flowers and leaves, V. cilicicum flowers, V. lasianthum flowers, V. mucronatum flowers, V. pycnostachyum flowers and V. splendidum flowers showed the highest inhibitory activities against the brine shrimp. On the other hand, the rest of the species did not show any remarkable cytotoxic activity.
  • Küçük Resim Yok
    Öğe
    Chemical constituents and cytotoxic activity of Ranunculus pedatus subsp. Pedatus
    (2012) Erdogan T.F.; Kivcak B.; Onur M.A.; Braca A.
    [No abstract available]
  • Küçük Resim Yok
    Öğe
    Fatty acid compositions and anti-inflammatory activities of Tripleurospermum parviflorum (Willd.) Pobed. and Tripleurospermum tenuifolium (Kit.)
    (ACG Publications, 2015) Erdogan T.F.; Akkol E.K.; Süntar I.; Gönenç T.M.; Kivçak B.
    In Turkish traditional medicine, Tripleurospermum species have been used for the treatment of inflammatory diseases. The present study was designed to investigate the anti-inflammatory potential and fatty acid composition of the extracts prepared from Tripleurospermum parviflorum (Willd.) Pobed. and T. tenuifolium (Kit.). Anti-inflammatory activity was assessed by using carrageenan-, and serotonin- induced hind paw edema and acetic acid-induced increase in capillary permeability models. The fatty acid compositions of the plants were investigated by gas chromatography (GC). EtOAc extracts of T. tenuifolium and T. parviflorum exerted notable inhibitory effect in the all in vivo anti-inflammatory activity models tested. Generally, C 16:0 palmitic acid and C 18:2 linoleic acid were found to be the major fatty acids in two species. Saturated fatty acids (SFAs) were found in higher amounts than monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) in two species. SFAs were determinated at 63.15% and 58.68% in T. tenuifolium and T. parviflorum, respectively. The high content of linoleic acid and palmitic acid may be primarily responsible for significant anti-inflammatory activity. The present study confirms the anti-inflammatory activity of T. parviflorum and T. tenuifolium. Further phytochemical and biological activity studies are needed for the determination of the active principle/s and anti-inflammatory activity mechanism. © 2015 ACG Publications. All rights reserved.